IFOM

Publications 2022

last update sept 2022
  1. Compact laboratory-based X-ray microscope enabling nondestructive 3D structure acquisition of mouse nephron with high speed and better user accessibility
    Kunishima, N., Takeda, Y., Hirose, R., Kume, S., Maeda, M., Oguchi, A., Yanagita, M., Shibuya, H., Tamura, M., Kataoka, Y., Murakawa, Y., Ito, K., Omote, K.
    (2022) Microscopy (Oxford, England), 71 (6), pp. 315-323. [35778966 ]

  2. miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response
    Cuttano, R., Colangelo, T., Guarize, J., Dama, E., Cocomazzi, M.P., Mazzarelli, F., Melocchi, V., Palumbo, O., Marino, E., Belloni, E., Montani, F., Vecchi, M., Barberis, M., Graziano, P., Pasquier, A., Sanz-Ortega, J., Montuenga, L.M., Carbonelli, C., Spaggiari, L., Bianchi, F.
    (2022) Journal of Hematology and Oncology, 15 (1), art. no. 178, . [ 36587234]

  3. Dynamic Interactomics by Cross-Linking Mass Spectrometry: Mapping the Daily Cell Life in Postgenomic Era
    Santorelli, L., Caterino, M., Costanzo, M.
    (2022) OMICS A Journal of Integrative Biology, 26 (12), pp. 633-649. [ 36445175]

  4. Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling
    Rizzello, C., Cancila, V., Sangaletti, S., Botti, L., Ratti, C., Milani, M., Dugo, M., Bertoni, F., Tripodo, C., Chiodoni, C., Colombo, M.P.
    (2022) Molecular Cancer, 21 (1), art. no. 215, . Cited 1 time. [ 36503430]

  5. Ca2+ binding to synapsin I regulates resting Ca2+ and recovery from synaptic depression in nerve terminals
    Moschetta, M., Ravasenga, T., De Fusco, A., Maragliano, L., Aprile, D., Orlando, M., Sacchetti, S., Casagrande, S., Lignani, G., Fassio, A., Baldelli, P., Benfenati, F.
    (2022) Cellular and Molecular Life Sciences, 79 (12), art. no. 600, . [36409372 ]

  6. Association between SARS-CoV?-2 RNAemia and dysregulated immune response in acutely ill hospitalized COVID-19 patients
    Rovito, R., Bono, V., Augello, M., Tincati, C., Mainoldi, F., Beaudoin-Bussières, G., Tauzin, A., Bianchi, S., Hadla, M., Yellenki, V., d’Arminio Monforte, A., Casola, S., Borghi, E., Finzi, A., Marchetti, G.
    (2022) Scientific Reports, 12 (1), art. no. 19658, . [ 36385627]

  7. F-actin organization and target constriction during primary macrophage phagocytosis is balanced by competing activity of myosin-I and myosin-II
    Barger, S.R., Vorselen, D., Gauthier, N.C., Theriot, J.A., Krendel, M.
    (2022) Molecular Biology of the Cell, 33 (14), . Cited 2 times. [ 36129777]

  8. Predictive Role of CD36 Expression in HER2-Positive Breast Cancer Patients Receiving Neoadjuvant Trastuzumab
    Ligorio, F., Di Cosimo, S., Verderio, P., Ciniselli, C.M., Pizzamiglio, S., Castagnoli, L., Dugo, M., Galbardi, B., Salgado, R., Loi, S., Michiels, S., Triulzi, T., Tagliabue, E., El-Abed, S., Izquierdo, M., De Azambuja, E., Nuciforo, P., Huober, J., Moscetti, L., Janni, W., Coccia-Portugal, M.A., Corsetto, P.A., Belfiore, A., Lorenzini, D., Daidone, M.G., Vingiani, A., Gianni, L., Pupa, S.M., Bianchini, G., Pruneri, G., Vernieri, C.
    (2022) Journal of the National Cancer Institute, 114 (12), pp. 1720-1727. Cited 3 times. [35789270 ]

  9. Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy
    Chiriaco, C., Donini, C., Cortese, M., Ughetto, S., Modica, C., Martinelli, I., Proment, A., Vitali, L., Fontani, L., Casucci, M., Comoglio, P.M., Giordano, S., Sangiolo, D., Leuci, V., Vigna, E.
    (2022) Journal of Experimental and Clinical Cancer Research, 41 (1), art. no. 309, . Cited 1 time. [ 36271379]

  10. Lateral confined growth of cells activates Lef1 dependent pathways to regulate cell-state transitions
    Yuan, L., Roy, B., Ratna, P., Uhler, C., Shivashankar, G.V.
    (2022) Scientific Reports, 12 (1), art. no. 17318, . [36243826 ]

  11. Publisher Correction: Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma (Nature Materials, (2019), 18, 11, (1252-1263), 10.1038/s41563-019-0425-1)
    Palamidessi, A., Malinverno, C., Frittoli, E., Corallino, S., Barbieri, E., Sigismund, S., Beznoussenko, G.V., Martini, E., Garre, M., Ferrara, I., Tripodo, C., Ascione, F., Cavalcanti-Adam, E.A., Li, Q., Di Fiore, P.P., Parazzoli, D., Giavazzi, F., Cerbino, R., Scita, G.
    (2022) Nature Materials, 21 (12), p. 1448. [36167801]

  12. Actomyosin contractility as a mechanical checkpoint for cell state transitions
    Venkatachalapathy, S., Sreekumar, D., Ratna, P., Shivashankar, G.V.
    (2022) Scientific Reports, 12 (1), art. no. 16063, . [36163393]

  13. The glycocalyx affects the mechanotransductive perception of the topographical microenvironment
    Chighizola, M., Dini, T., Marcotti, S., D’Urso, M., Piazzoni, C., Borghi, F., Previdi, A., Ceriani, L., Folliero, C., Stramer, B., Lenardi, C., Milani, P., Podestà, A., Schulte, C.
    (2022) Journal of Nanobiotechnology, 20 (1), art. no. 418, . Cited 3 times. [36123687]

  14. Cancer cell histone density links global histone acetylation, mitochondrial proteome and histone acetylase inhibitor sensitivity
    Bruhn, C., Bastianello, G., Foiani, M.
    (2022) Communications Biology, 5 (1), art. no. 882, . Cited 1 time. [36030322]

  15. NR1H3 (LXRα) is associated with pro-inflammatory macrophages, predicts survival and suggests potential therapeutic rationales in diffuse large b-cell lymphoma
    Vegliante, M.C., Mazzara, S., Zaccaria, G.M., De Summa, S., Esposito, F., Melle, F., Motta, G., Sapienza, M.R., Opinto, G., Volpe, G., Bucci, A., Gargano, G., Enjuanes, A., Tabanelli, V., Fiori, S., Minoia, C., Clemente, F., Negri, A., Gulino, A., Morello, G., Scattone, A., Zito, A.F., Tommasi, S., Agostinelli, C., Vitolo, U., Chiappella, A., Barbui, A.M., Derenzini, E., Zinzani, P.L., Casadei, B., Rivas-Delgado, A., López-Guillermo, A., Campo, E., Moschetta, A., Guarini, A., Pileri, S.A., Ciavarella, S.
    (2022) Hematological Oncology, 40 (5), pp. 864-875. Cited 3 times. [35850118]

  16. A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions
    Donzelli, S., Cioce, M., Sacconi, A., Zanconato, F., Daralioti, T., Goeman, F., Orlandi, G., Di Martino, S., Fazio, V.M., Alessandrini, G., Telera, S., Carosi, M., Ciliberto, G., Botti, C., Strano, S., Piccolo, S., Blandino, G.
    (2022) Molecular Cancer, 21 (1), art. no. 152, . Cited 1 time. [35869553]

  17. Direct cleavage of caspase-8 by herpes simplex virus 1 tegument protein US11
    Musarra-Pizzo, M., Pennisi, R., Lombardo, D., Velletri, T., Sciortino, M.T.
    (2022) Scientific Reports, 12 (1), art. no. 12317, . Cited 1 time. [35853963]

  18. CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer
    Filippone, M.G., Gaglio, D., Bonfanti, R., Tucci, F.A., Ceccacci, E., Pennisi, R., Bonanomi, M., Jodice, G., Tillhon, M., Montani, F., Bertalot, G., Freddi, S., Vecchi, M., Taglialatela, A., Romanenghi, M., Romeo, F., Bianco, N., Munzone, E., Sanguedolce, F., Vago, G., Viale, G., Di Fiore, P.P., Minucci, S., Alberghina, L., Colleoni, M., Veronesi, P., Tosoni, D., Pece, S.
    (2022) Nature Communications, 13 (1), art. no. 2642, . Cited 6 times. [35550508]

  19. Breast cancer risks associated with missense variants in breast cancer susceptibility genes
    Dorling, L., Carvalho, S., Allen, J., Parsons, M.T., Fortuno, C., González-Neira, A., Heijl, S.M., Adank, M.A., Ahearn, T.U., Andrulis, I.L., Auvinen, P., Becher, H., Beckmann, M.W., Behrens, S., Bermisheva, M., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Bremer, M., Briceno, I., Camp, N.J., Campbell, A., Castelao, J.E., Chang-Claude, J., Chanock, S.J., Chenevix-Trench, G., Collée, J.M., Czene, K., Dennis, J., Dörk, T., Eriksson, M., Evans, D.G., Fasching, P.A., Figueroa, J., Flyger, H., Gabrielson, M., Gago-Dominguez, M., García-Closas, M., Giles, G.G., Glendon, G., Guénel, P., Gündert, M., Hadjisavvas, A., Hahnen, E., Hall, P., Hamann, U., Harkness, E.F., Hartman, M., Hogervorst, F.B.L., Hollestelle, A., Hoppe, R., Howell, A., Jakubowska, A., Jung, A., Khusnutdinova, E., Kim, S.-W., Ko, Y.-D., Kristensen, V.N., Lakeman, I.M.M., Li, J., Lindblom, A., Loizidou, M.A., Lophatananon, A., Lubi?ski, J., Luccarini, C., Madsen, M.J., Mannermaa, A., Manoochehri, M., Margolin, S., Mavroudis, D., Milne, R.L., Mohd Taib, N.A., Muir, K., Nevanlinna, H., Newman, W.G., Oosterwijk, J.C., Park, S.K., Peterlongo, P., Radice, P., Saloustros, E., Sawyer, E.J., Schmutzler, R.K., Shah, M., Sim, X., Southey, M.C., Surowy, H., Suvanto, M., Tomlinson, I., Torres, D., Truong, T., van Asperen, C.J., Waltes, R., Wang, Q., Yang, X.R., Pharoah, P.D.P., Schmidt, M.K., Benitez, J., Vroling, B., Dunning, A.M., Teo, S.H., Kvist, A., de la Hoya, M., Devilee, P., Spurdle, A.B., Vreeswijk, M.P.G., Easton, D.F., NBCS Collaborators, kConFab Investigators, SGBCC Investigators
    (2022) Genome Medicine, 14 (1), art. no. 51, . Cited 5 times. [35585550]

  20. The transcription factor PREP1(PKNOX1) regulates nuclear stiffness, the expression of LINC complex proteins and mechanotransduction
    Purushothaman, D., Bianchi, L.F., Penkov, D., Poli, A., Li, Q., Vermezovic, J., Pramotton, F.M., Choudhary, R., Pennacchio, F.A., Sommariva, E., Foiani, M., Gauthier, N., Maiuri, P., Blasi, F.
    (2022) Communications Biology, 5 (1), art. no. 456, . [35550602]

  21. Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase
    Joseph, C.R., Dusi, S., Giannattasio, M., Branzei, D.
    (2022) Nature Communications, 13 (1), art. no. 2480, . Cited 1 time. [35513396]

  22. TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance
    Buemi, V., Schillaci, O., Santorsola, M., Bonazza, D., Broccia, P.V., Zappone, A., Bottin, C., Dell’Omo, G., Kengne, S., Cacchione, S., Raffa, G.D., Piazza, S., di Fagagna, F.A., Benetti, R., Cortale, M., Zanconati, F., Del Sal, G., Schoeftner, S.
    (2022) Nature Communications, 13 (1), art. no. 2302, . Cited 5 times. [35484160]

  23. EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes
    Copperi, F., Schleis, I., Roumain, M., Muccioli, G.G., Casola, S., Klingenspor, M., Pfeifer, A., Gnad, T.
    (2022) Communications Biology, 5 (1), art. no. 280, . Cited 1 time. [35351968]

  24. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host
    Alexa, A., Sok, P., Gross, F., Albert, K., Kobori, E., Póti, Á.L., Gógl, G., Bento, I., Kuang, E., Taylor, S.S., Zhu, F., Ciliberto, A., Reményi, A.
    (2022) Nature Communications, 13 (1), art. no. 472, . Cited 5 times. [35078976]

  25. SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation
    Jevtic, Z., Matafora, V., Casagrande, F., Santoro, F., Minucci, S., Garre’, M., Rasouli, M., Heidenreich, O., Musco, G., Schwaller, J., Bachi, A.
    (2022) Journal of Experimental and Clinical Cancer Research, 41 (1), art. no. 34, . Cited 6 times. [35073946]

  26. BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1
    Chen, D., Gervai, J.Z., Póti, Á., Németh, E., Szeltner, Z., Szikriszt, B., Gyüre, Z., Zámborszky, J., Ceccon, M., d’Adda di Fagagna, F., Szallasi, Z., Richardson, A.L., Szüts, D.
    (2022) Nature Communications, 13 (1), art. no. 226, . Cited 5 times. [35017534]

  27. POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    Schrempf, A., Bernardo, S., Arasa Verge, E.A., Ramirez Otero, M.A., Wilson, J., Kirchhofer, D., Timelthaler, G., Ambros, A.M., Kaya, A., Wieder, M., Ecker, G.F., Winter, G.E., Costanzo, V., Loizou, J.I.
    (2022) Cell Reports, 41 (9), art. no. 111716, . Cited 2 times. [36400033]

  28. A theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces
    Sadhu, R.K., Barger, S.R., Peni?, S., Igli?, A., Krendel, M., Gauthier, N.C., Gov, N.S.
    (2022) Soft Matter, 19 (1), pp. 31-43. [36472164]

  29. POLθ prevents MRE11-NBS1-CtIP?-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps
    Mann, A., Ramirez-Otero, M.A., De Antoni, A., Hanthi, Y.W., Sannino, V., Baldi, G., Falbo, L., Schrempf, A., Bernardo, S., Loizou, J., Costanzo, V.
    (2022) Molecular Cell, 82 (22), pp. 4218-4231.e8. Cited 3 times. [36400008]

  30. Immunothrombosis and vascular heterogeneity in cerebral cavernous malformation
    Globisch, M.A., Onyeogaziri, F.C., Jauhiainen, S., Yau, A.C.Y., Orsenigo, F., Conze, L.L., Arce, M., Corada, M., Smith, R.O., Rorsman, C., Sundell, V., Fernando, D., Daniel, G., Mattsson, O., Savander, H., Wanders, A., Rezai Jahromi, B., Laakso, A., Niemelä, M., Dejana, E., Magnusson, P.U.
    (2022) Blood, 140 (20), pp. 2154-2169. Cited 2 times. [35981497]

  31. Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism
    Gritti, I., Basso, V., Rinchai, D., Corigliano, F., Pivetti, S., Gaviraghi, M., Rosano, D., Mazza, D., Barozzi, S., Roncador, M., Parmigiani, G., Legube, G., Parazzoli, D., Cittaro, D., Bedognetti, D., Mondino, A., Segalla, S., Tonon, G.
    (2022) EMBO Journal, 41 (22), art. no. e108040, . Cited 1 time. [36215697]

  32. Case Report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer
    Mauri, G., Patelli, G., Gori, V., Lauricella, C., Mussolin, B., Amatu, A., Bencardino, K., Tosi, F., Bonazzina, E., Bonoldi, E., Bardelli, A., Siena, S., Sartore-Bianchi, A.
    (2022) Frontiers in Oncology, 12, art. no. 1030232, . [37056342]

  33. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
    Chen, L., Roake, C.M., Maccallini, P., Bavasso, F., Dehghannasiri, R., Santonicola, P., Mendoza-Ferreira, N., Scatolini, L., Rizzuti, L., Esposito, A., Gallotta, I., Francia, S., Cacchione, S., Galati, A., Palumbo, V., Kobin, M.A., Tartaglia, G.G., Colantoni, A., Proietti, G., Wu, Y., Hammerschmidt, M., De Pittà, C., Sales, G., Salzman, J., Pellizzoni, L., Wirth, B., Di Schiavi, E., Gatti, M., Artandi, S.E., Raffa, G.D.
    (2022) Nucleic Acids Research, 50 (21), pp. 12400-12424. [35947650]

  34. Characterization of Mitochondrial Alterations in Aicardi–Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes
    Dragoni, F., Garau, J., Sproviero, D., Orcesi, S., Varesio, C., De Siervi, S., Gagliardi, S., Cereda, C., Pansarasa,O.
    (2022) International Journal of Molecular Sciences, 23 (22), art. no. 14482, . Cited 1 time. [36430958]

  35. Role of Endothelial Regeneration and Overloading of Enterocytes with Lipids in Capturing of Lipoproteins by Basement Membrane of Rat Aortic Endothelium
    Sesorova, I.S., Sesorov, V.V., Soloviev, P.B., Lakunin, K.Y., Dimov, I.D., Mironov, A.A.
    (2022) Biomedicines, 10 (11), art. no. 2858, . Cited 4 times. [36359378]

  36. Effect of the First Feeding on Enterocytes of Newborn Rats
    Nikonova, M.A., Sesorova, I.S., Dimov, I.D., Karelina, N.R., Mironov, A.A.
    (2022) International Journal of Molecular Sciences, 23 (22), art. no. 14179, . Cited 4 times. [36430658 ]

  37. DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression
    Muñoz, J.C., Beckerman, I., Choudhary, R., Bouvier, L.A., Muñoz, M.J.
    (2022) Genes, 13 (11), art. no. 1951, . [36360188]

  38. Tumor Organoids as a Research Tool: How to Exploit Them
    Booij, T.H., Cattaneo, C.M., Hirt, C.K.
    (2022) Cells, 11 (21), art. no. 3440, . Cited 1 time [36359838]

  39. Response to: Dealing with menstrual cycle in sport: stop finding excuses to exclude women from research
    Nardon, M., Venturelli, M., Ruzzante, F., Longo, V., Bertucco, M.
    (2022) European Journal of Applied Physiology, 122 (11), pp. 2491-2492. [35918557]

  40. An overview of structural approaches to study therapeutic RNAs
    Mollica, L., Cupaioli, F.A., Rossetti, G., Chiappori, F.
    (2022) Frontiers in Molecular Biosciences, 9, art. no. 1044126, . [36387283]

  41. Long-term effects of early postnatal stress on Sertoli cells
    Thumfart, K.M., Lazzeri, S., Manuella, F., Mansuy, I.M.
    (2022) Frontiers in Genetics, 13, art. no. 1024805, . Cited 1 time. [36353105]

  42. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers
    Hakkaart, C., Pearson, J.F., Marquart, L., Dennis, J., Wiggins, G.A.R., Barnes, D.R., Robinson, B.A., Mace, P.D., Aittomäki, K., Andrulis, I.L., Arun, B.K., Azzollini, J., Balmaña, J., Barkardottir, R.B., Belhadj, S., Berger, L., Blok, M.J., Boonen, S.E., Borde, J., Bradbury, A.R., Brunet, J., Buys, S.S., Caligo, M.A., Campbell, I., Chung, W.K., Claes, K.B.M., Collonge-Rame, M.-A., Cook, J., Cosgrove, C., Couch, F.J., Daly, M.B., Dandiker, S., Davidson, R., de la Hoya, M., de Putter, R., Delnatte, C., Dhawan, M., Diez, O., Ding, Y.C., Domchek, S.M., Donaldson, A., Eason, J., Easton, D.F., Ehrencrona, H., Engel, C., Evans, D.G., Faust, U., Feliubadaló, L., Fostira, F., Friedman, E., Frone, M., Frost, D., Garber, J., Gayther, S.A., Gehrig, A., Gesta, P., Godwin, A.K., Goldgar, D.E., Greene, M.H., Hahnen, E., Hake, C.R., Hamann, U., Hansen, T.V.O., Hauke, J., Hentschel, J., Herold, N., Honisch, E., Hulick, P.J., Imyanitov, E.N., Isaacs, C., Izatt, L., Izquierdo, A., Jakubowska, A., James, P.A., Janavicius, R., John, E.M., Joseph, V., Karlan, B.Y., Kemp, Z., Kirk, J., Konstantopoulou, I., Koudijs, M., Kwong, A., Laitman, Y., Lalloo, F., Lasset, C., Lautrup, C., Lazaro, C., Legrand, C., Leslie, G., Lesueur, F., Mai, P.L., Manoukian, S., Mari, V., Martens, J.W.M., McGuffog?, L., Mebirouk, N., Meindl, A., Miller, A., Montagna, M., Moserle, L., Mouret-Fourme, E., Musgrave, H., Nambot, S., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Yie, J.N.Y., Nguyen-Dumont, T., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O.I., Osorio, A., Ott, C.-E., Park, S.K., Parsons, M.T., Pedersen, I.S., Peixoto, A., Perez-Segura, P., Peterlongo, P., Pocza, T., Radice, P., Ramser, J., Rantala, J., Rodriguez, G.C., Rønlund, K., Rosenberg, E.H., Rossing, M., Schmutzler, R.K., Shah, P.D., Sharif, S., Sharma, P., Side, L.E., Simard, J., Singer, C.F., Snape, K., Steinemann, D., Stoppa-Lyonnet, D., Sutter, C., Tan, Y.Y., Teixeira, M.R., Teo, S.H., Thomassen, M., Thull, D.L., Tischkowitz, M., Toland, A.E., Trainer, A.H., Tripathi, V., Tung, N., van Engelen, K., van Rensburg, E.J., Vega, A., Viel, A., Walker, L., Weitzel, J.N., Wevers, M.R., Chenevix-Trench, G., Spurdle, A.B., Antoniou, A.C., Walker, L.C., GEMO Study Collaborators, EMBRACE Collaborators, SWE-BRCA Investigators, kConFab Investigators, HEBON Investigators
    (2022) Communications biology, 5 (1), p. 1061. Cited 1 time. [36203093]

  43. Breakfast keeps hunger in check
    Brandhorst, S., Longo, V.D.
    (2022) Cell Metabolism, 34 (10), pp. 1420-1421. Cited 1 time. [36198286]

  44. Pharmacological screening identified promising combination partners in marginal zone lymphoma models with secondary resistance to BTK and PI3K inhibitors
    Arribas, A., Vultaggio, S., Andronache, A., Robusto, M., Fancelli, D., Cannas, E., Spriano, F., Tarantelli, C., Rossi, D., Zucca, E., Stathis, A., Varasi, M., Mercurio, C., Bertoni, F.
    (2022) European Journal of Cancer, 174, p. S108. [www.ejcancer.com ]

  45. The PSI Domain of the MET Oncogene Encodes a Functional Disulfide Isomerase Essential for the Maturation of the Receptor Precursor
    Altintas, D.M., Gallo, S., Basilico, C., Cerqua, M., Bocedi, A., Vitacolonna, A., Botti, O., Casanova, E., Rancati, I., Milanese, C., Notari, S., Gambardella, G., Ricci, G., Mastroberardino, P.G., Boccaccio, C., Crepaldi, T., Comoglio, P.M.
    (2022) International Journal of Molecular Sciences, 23 (20), art. no. 12427 . [36293286]

  46. Identification of an effective chemotherapy and DNA damage response inhibitor combination for diffuse large b cell lymphoma
    Chan, A., Anbuselvan, A., Upadhyayula, S.S., Jemimah, S., Jaynes, P., Hoppe, M.M., Wardyn, J.D., Goh, J., Bertolazzi, G., Foiani, M., O'Connor, M.J., Chow, E.K., Tripodo, C., Jeyasekharan, A.D.
    (2022) European Journal of Cancer, 174, pp. S55-S56. [34162179]

  47. ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA
    Varone, E., Chernorudskiy, A., Cherubini, A., Cattaneo, A., Bachi, A., Fumagalli, S., Erol, G., Gobbi, M., Lenardo, M.J., Borgese, N., Zito, E.
    (2022) Redox Biology, 56, art. no. 102455, . Cited 2 times. [36063727]

  48. METΔ14 promotes a ligand-dependent, AKT-driven invasive growth
    Cerqua, M., Botti, O., Arigoni, M., Gioelli, N., Serini, G., Calogero, R., Boccaccio, C., Comoglio, P.M., Altintas, D.M.
    (2022) Life Science Alliance, 5 (10), art. no. e202201409, . Cited 2 times. [35636967]

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  96. Nutrition, longevity and disease: From molecular mechanisms to interventions
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  97. DUX4 is a multifunctional factor priming human embryonic genome activation
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  98. Comparison of the Cisterna Maturation-Progression Model with the Kiss-and-Run Model of Intra-Golgi Transport: Role of Cisternal Pores and Cargo Domains
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  99. Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
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  100. PillarX?: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State
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  101. Document Type: Article Publication Stage: Final
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  110. Efficacy of Retreatment with Oxaliplatin-Based Regimens in Metastatic Colorectal Cancer Patients: The RETROX-CRC Retrospective Study
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  111. Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
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  112. Dietary intake of cyanidin-3-glucoside induces a long-lasting cardioprotection from ischemia/reperfusion injury by altering the microbiota
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  113. Exploring the association with disease recurrence of miRNAs predictive of colorectal cancer
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  114. Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer
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  116. Myosin VI regulates ciliogenesis by promoting the turnover of the centrosomal/satellite protein OFD1
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  120. Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance
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  122. Opinion: On the Way towards the New Paradigm of Atherosclerosis
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  123. The H. pylori CagA? Oncoprotein Induces DNA Double Strand Breaks through Fanconi Anemia Pathway Downregulation and Replication Fork Collapse
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  124. Association between IGF-1 levels ranges and all-cause mortality: A meta-analysis
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  125. Broadly Applicable Hydrogel Fabrication Procedures Guided by YAP/TAZ-Activity Reveal Stiffness, Adhesiveness, and Nuclear Projected Area as Checkpoints for Mechanosensing
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  126. Rare germline copy number variants (CNVs) and breast cancer risk
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  127. Enrichment of DNA replication intermediates by EdU? pull down
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  128. Prediction of the cell-type-specific transcription of non-coding RNAs from genome sequences via machine learning
    Koido, M., Hon, C.-C., Koyama, S., Kawaji, H., Murakawa, Y., Ishigaki, K., Ito, K., Sese, J., Parrish, N.F., Kamatani, Y., Carninci, P., Terao, C.
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  129. Cellular Polarity Transmission to the Nucleus
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    (2022) Results and Problems in Cell Differentiation, 70, pp. 597-606. [36348123]

  130. Fasting and cancer: from yeast to mammals
    Di Tano, M., Longo, V.D.
    (2022) International Review of Cell and Molecular Biology, 373, pp. 81-106. [36283768]

  131. Topology of RNA:DNA Hybrids and R-Loops in Yeast
    Achar, Y.J., Foiani, M.
    (2022) Methods in Molecular Biology, 2528, pp. 317-328. [35704201]

  132. Application of histology-agnostic treatments in metastatic colorectal cancer
    Sartore-Bianchi, A., Agostara, A.G., Patelli, G., Mauri, G., Pizzutilo, E.G., Siena, S.
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  133. Dynamics of Bacterial Chromosomes by Locus Tracking in Fluorescence Microscopy
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  134. An update on clinical applications of iPSCs from a genomic point of view
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  135. Correction: The impact of a fasting mimicking diet on the metabolic health of a prospective cohort of patients with prostate cancer: a pilot implementation study
    Fay-Watt, V., O’Connor, S., Roshan, D., Romeo, A.C., Longo, V.D., Sullivan, F.J.
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  136. The impact of a fasting mimicking diet on the metabolic health of a prospective cohort of patients with prostate cancer: a pilot implementation study
    Fay-Watt, V., O’Connor, S., Roshan, D., Romeo, A.C., Longo, V.D., Sullivan, F.J.
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  137. Vps30/Atg6/BECN1 at the crossroads between cell metabolism and DNA damage response
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  138. Pathology of tumors associated with pathogenic germline variants in 9 breast cancer susceptibility genes
    Mavaddat, N., Dorling, L., Carvalho, S., Allen, J., González-Neira, A., Keeman, R., Bolla,M.K., Dennis, J., Wang, Q., Ahearn, T.U., Andrulis, I.L., Beckmann, M.W., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Bogdanova, N.V., Bojesen, S.E., Briceno, I., Brüning, T., Camp, N.J., Campbell, A., Castelao, J.E., Chang-Claude, J., Chanock, S.J., Chenevix-Trench, G., Christiansen, H., Czene, K., Dörk, T., Eriksson, M., Evans, D.G., Fasching, P.A., Figueroa, J.D., Flyger, H., Gabrielson, M., Gago-Dominguez, M., Geisler, J., Giles, G.G., Guénel, P., Hadjisavvas, A., Hahnen, E., Hall, P., Hamann, U., Hartikainen, J.M., Hartman, M., Hoppe, R., Howell, A., Jakubowska, A., Jung, A., Khusnutdinova, E.K., Kristensen, V.N., Li, J., Lim, S.H., Lindblom, A., Loizidou, M.A., Lophatananon, A., Lubi?ski, J., Madsen, M.J., Mannermaa, A., Manoochehri, M., Margolin, S., Mavroudis, D., Milne, R.L., Taib, N.A.M., Morra, A., Muir, K., Obi, N., Osorio, A., Park-Simon, T.-W., Peterlongo, P., Radice, P., Saloustros, E., Sawyer, E.J., Schmutzler, R.K., Shah, M., Sim, X., Southey, M.C., Thorne, H., Tomlinson, I., Torres, D., Truong, T., Yip, C.H., Spurdle, A.B., Vreeswijk, M.P.G., Dunning, A.M., García-Closas, M., Pharoah, P.D.P., Kvist, A., Muranen, T.A., Nevanlinna, H., Teo, S.H., Devilee, P., Schmidt, M.K., Easton, D.F.
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  139. Extracellular vesicles: The key for precision medicine in glioblastoma
    Del Bene, M., Osti, D., Faletti, S., Beznoussenko, G.V., DiMeco?, F., Pelicci, G.
    (2022) Neuro-Oncology, 24 (2), pp. 184-196. Cited 7 times. [34581817]

  140. Volume growth in animal cells is cell cycle dependent and shows additive fluctuations
    Cadart, C., Venkova, L., Piel, M., Cosentino Lagomarsino, M.
    (2022) eLife, 11, art. no. e70816, . Cited 2 times. [35088713]

  141. Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
    Vernieri, C., Fucà, G., Ligorio, F., Huber, V., Vingiani, A., Iannelli, F., Raimondi, A., Rinchai, D., Frigè, G., Belfiore, A., Lalli, L., Chiodoni, C., Cancila, V., Zanardi, F., Ajazi, A., Cortellino, S., Vallacchi, V., Squarcina, P., Cova, A., Pesce, S., Frati, P., Mall, R., Corsetto, P.A., Rizzo, A.M., Ferraris, C., Folli, S., Garassino, M.C., Capri, G., Bianchi, G., Colombo, M.P., Minucci, S., Foiani, M., Longo, V.D., Apolone, G., Torri, V., Pruneri, G., Bedognetti, D., Rivoltini, L., de Braud, F.
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  142. Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores
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  143. Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Li, H., Engel, C., de la Hoya, M., Peterlongo, P., Yannoukakos, D., Livraghi, L., Radice, P., Thomassen, M., Hansen, T.V.O., Gerdes, A.-M., Nielsen, H.R., Caputo, S.M., Zambelli, A., Borg, A., Solano, A., Thomas, A., Parsons, M.T., Antoniou, A.C., Leslie, G., Yang, X., Chenevix-Trench, G., Caldes, T., Kwong, A., Pedersen, I.S., Lautrup, C.K., John, E.M., Terry, M.B., Hopper, J.L., Southey, M.C., Andrulis, I.L., Tischkowitz, M., Janavicius, R., Boonen, S.E., Kroeldrup, L., Varesco, L., Hamann, U., Vega, A., Palmero, E.I., Garber, J., Montagna, M., Van Asperen, C.J., Foretova, L., Greene, M.H., Selkirk, T., Moller, P., Toland, A.E., Domchek, S.M., James, P.A., Thorne, H., Eccles, D.M., Nielsen, S.M., Manoukian, S., Pasini, B., Caligo, M.A., Lazaro, C., Kirk, J., Wappenschmidt, B., Spurdle, A.B., Couch, F.J., Schmutzler, R., Goldgar, D.E., ENIGMA Consortium, CIMBA Consortium
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  144. Recurrent Spliceosome Mutations in Cancer: Mechanisms and Consequences of Aberrant Splice Site Selection
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  145. Direct RNA Nanopore Sequencing of SARS-CoV?-2 Extracted from Critical Material from Swabs
    Vacca, D., Fiannaca, A., Tramuto, F., Cancila, V., La Paglia, L., Mazzucco, W., Gulino, A., La Rosa, M., Maida, C.M., Morello, G., Belmonte, B., Casuccio, A., Maugeri, R., Iacopino, G., Balistreri, C.R., Vitale, F., Tripodo, C., Urso, A.
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  146. Delta-Radiomics Predicts Response to First-Line Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients with Liver Metastases
    Giannini, V., Pusceddu, L., Defeudis, A., Nicoletti, G., Cappello, G., Mazzetti, S., Sartore-Bianchi, A., Siena, S., Vanzulli, A., Rizzetto, F., Fenocchio, E., Lazzari, L., Bardelli, A., Marsoni, S., Regge, D.
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  147. Cancer-related intracellular signalling pathways activated by doxorubicin/cyclodextrin-graphene-based nanomaterials
    Pennisi, R., Musarra-Pizzo, M., Velletri, T., Mazzaglia, A., Neri, G., Scala, A., Piperno, A., Sciortino, M.T.
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  148. Impact of diabetes and metformin use on enteropancreatic neuroendocrine tumors: Post hoc analysis of the clarinet study
    Pusceddu, S., Vernieri, C., Di Maio, M., Prinzi, N., Torchio, M., Corti, F., Coppa, J., Buzzoni, R., Di Bartolomeo, M., Milione, M., Regnault, B., Thanh, X.-M.T., Mazzaferro, V., de Braud, F.
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  149. PA28γ–20S proteasome is a proteolytic complex committed to degrade unfolded proteins
    Frayssinhes, J.-Y.A., Cerruti, F., Laulin, J., Cattaneo, A., Bachi, A., Apcher, S., Coux, O., Cascio, P.
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  150. The E-Syt3 cleavage and traffic uncovers the primordial cisterna, a new organelle that mothers the lipid droplets in the adipocyte
    Lalioti, V., Beznoussenko, G.V., Mironov, A.A., Sandoval, I.V.
    (2022) Traffic, 23 (1), pp. 21-41. Cited 2 times. [34693607]

  151. PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism
    Simula, L., Antonucci, Y., Scarpelli, G., Cancila, V., Colamatteo, A., Manni, S., De Angelis, B., Quintarelli, C., Procaccini, C., Matarese, G., Tripodo, C., Campello, S.
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  152. Cap analysis of gene expression (CAGE) and noncoding regulatory elements
    Guerrini, M.M., Oguchi, A., Suzuki, A., Murakawa, Y.
    (2022) Seminars in Immunopathology, 44 (1), pp. 127-136. Cited 1 time.[34468849]

  153. Preface
    Bicciato, S., Ferrari, F.
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  154. Visualizing and Annotating Hi-C Data
    Pal, K., Ferrari, F.
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