IFOM Nils Gauthier Lab

Nils Gauthier Lab

Nils Gauthier

Nils Gauthier Joined IFOM in January 2016 to start a research group focused on Mechano-Oncology using interdisciplinary approaches to study the biophysical properties of tumor progression. Nils Gauthier started training in 2000 at the University of Nice Sophia-Antipolis in France for his PhD under the supervision of Professor Patrice Boquet. The goal of his PhD was to decipher the endocytic road of Helicobacter-pylori VacA cytotoxin into its target epithelial cells. read more

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Mechano-Oncology

Our goal is to understand the roles of mechanical signals generated at the interface between membrane and cytoskeleton during tumor-associated biological events. This way of thinking about cancer is directly linked to the field of mechanobiology (i.e. the study of the role of mechanical forces in biological events) and to the lack of knowledge on the potential role of physical forces and parameters during tumor progression. read more

Laboratory location: Milan, Italy

Recent publications

  • Gauthier NC*, Roca-Cusachs P*.
    Mechanosensing at integrin-mediated cell-matrix adhesions: from molecular to integrated mechanisms.
    Curr Opin Cell Biol. 2018 Jan 26;50:20-26.
    * Corresponding authors
  • Pontes B*, Monzo P, Gauthier NC*.
    Membrane tension: A challenging but universal physical parameter in cell biology.
    Semin Cell Dev Biol. 2017 Nov;71:30-41.
    * Corresponding authors
  • Pontes B, Monzo P, Gole L, Le Roux AL, Kosmalska AJ, Tam ZY, Luo W, Kan S, Viasnoff V, Roca-Cusachs P, Tucker-Kellogg L, Gauthier NC*.
    Membrane tension controls adhesion positioning at the leading edge of cells.
    J Cell Biol. 2017 Sep 4;216(9):2959-2977.
    * Corresponding author

Group members

Research Scientist
Dr Pascale Monzo
Post Doc
Dr Andrea Ghisleni
PhD students
Camilla Galli

(update: Feb 2018)

Collaboration

  • MBI Singapore, Singapore Charlotte Guetta, studente PhD (codirezione con Pr Benoit Ladoux)
  • IBEC Barcellona Spagna Anita Kosmalska, studente PhD (codirezione con Dottor Pere Roca-Cusachs)
  • State University of New York (SUNY), Sarah Barger PhD student (collaboration with Dr Mira Krendel)

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