IFOM Publications 2012 « Research
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Publications 2012

Chronological order - last update November 2014
  1. 5-Methylcytosine DNA demethylation: more than losing a methyl group.
    Franchini Don-Marc - Schmitz Kerstin-Maike - Petersen-Mahrt Svend K
    Annual Review of Genetics | 2012 jan 1 | doi: 10.1146/annurev-genet-110711-155451 | ISSN: 1545-2948 | Vol. 46 Issue nd
    [PMID: 22974304] IF 17,436

  2. Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response.
    Cardone Luca - Bardelli Alberto - Avvedimento Vittorio Enrico K
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0037526 | ISSN: 1932-6203 | Vol. 7 Issue 5
    [PMID: 22662165] IF 3,730

  3. Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes.
    Wallin Jeffrey J - Guan Jane - Edgar Kyle A - Zhou Wei - Francis Ross - Torres Anthony C - Haverty Peter M - Eastham-Anderson Jeffrey - Arena Sabrina - Bardelli Alberto - Griffin Sue - Goodall John E - Grimshaw Kyla M - Hoeflich Klaus P - Torrance Christopher - Belvin Marcia - Friedman Lori S
    Annual Review of Genetics | 2012 jan 1 | doi: 10.1146/annurev-genet-110711-155451 | ISSN: 1545-2948 | Vol. 46 Issue nd
    [PMID: 22570710] IF 3,730

  4. AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud.
    Rangam Gopinath - Schmitz Kerstin-Maike - Cobb Alexander J A - Petersen-Mahrt Svend K
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0043279 | ISSN: 1932-6203 | Vol. 7 Issue 8
    [PMID: 22974304] IF 3,730

  5. Circulating microRNAs: next-generation biomarkers for early lung cancer detection.
    Bianchi F - Nicassio F - Veronesi G - di Fiore P P
    Ecancermedicalscience | 2012 jan 1 | doi: 10.3332/ecancer.2012.246 | ISSN: 1754-6605 | Vol. 6 Issue nd
    [PMID: 22518197]

  6. Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.
    Antoniou Antonis C - Kuchenbaecker Karoline B - Soucy Penny - Beesley Jonathan - Chen Xiaoqing - McGuffog Lesley - Lee Andrew - Barrowdale Daniel - Healey Sue - Sinilnikova Olga M - Caligo Maria A - Loman Niklas - Harbst Katja - Lindblom Annika - Arver Brita - Rosenquist Richard - Karlsson Per - Nathanson Kate - Domchek Susan - Rebbeck Tim - Jakubowska Anna - Lubinski Jan - Jaworska Katarzyna - Durda Katarzyna - El?bieta Z?owowcka-Per?owska - Osorio Ana - Dur án Mercedes - Andrés Raquel - Benítez Javier - Hamann Ute - Hogervorst Frans B - van Os Theo A - Verhoef Senno - Meijers-Heijboer Hanne E J - Wijnen Juul - Gómez Garcia Encarna B - Ligtenberg Marjolijn J - Kriege Mieke - Collée J Margriet - Ausems Margreet G E M - Oosterwijk Jan C - Peock Susan - Frost Debra - Ellis Steve D - Platte Radka - Fineberg Elena - Evans D Gareth - Lalloo Fiona - Jacobs Chris - Eeles Ros - Adlard Julian - Davidson Rosemarie - Cole Trevor - Cook Jackie - Paterson Joan - Douglas Fiona - Brewer Carole - Hodgson Shirley - Morrison Patrick J - Walker Lisa - Rogers Mark T - Donaldson Alan - Dorkins Huw - Godwin Andrew K - Bove Betsy - Stoppa-Lyonnet Dominique - Houdayer Claude - Buecher Bruno - de Pauw Antoine - Mazoyer Sylvie - Calender Alain - Léoné Mélanie - Bressac-de Paillerets Brigitte - Caron Olivier - Sobol Hagay - Frenay Marc - Prieur Fabienne - Ferrer Sandra U - Mortemousque Isabelle - Buys Saundra - Daly Mary - Miron Alexander - Terry Mary U - Hopper John L - John Esther M - Southey Melissa - Goldgar David - Singer Christian F - Fink-Retter Anneliese - Tea Muy-Kheng - Kaulich Daphne U - Hansen Thomas V - Nielsen Finn C - Barkardottir Rosa B - Gaudet Mia - Kirchhoff Tomas - Joseph Vijai - Dutra-Clarke Ana - Offit Kenneth - Piedmonte Marion - Kirk Judy - Cohn David - Hurteau Jean - Byron John - Fiorica James - Toland Amanda E - Montagna Marco - Oliani Cristina - Imyanitov Evgeny - Isaacs Claudine - Tihomirova Laima - Blanco Ignacio - Lazaro Conxi - Teulé Alex - Valle J Del - Gayther Simon A - Odunsi Kunle - Gross Jenny - Karlan Beth Y - Olah Edith - Teo Soo-Hwang - Ganz Patricia A - Beattie Mary S - Dorfling Cecelia M - van Rensburg Elizabeth U - Diez Orland - Kwong Ava - Schmutzler Rita K - Wappenschmidt Barbara - Engel Christoph - Meindl Alfons - Ditsch Nina - Arnold Norbert - Heidemann Simone - Niederacher Dieter - Preisler-Adams Sabine - Gadzicki Dorothea - Varon-Mateeva Raymonda - Deissler Helmut - Gehrig Andrea - Sutter Christian - Kast Karin - Fiebig Britta - Schäfer Dieter - Caldes Trinidad - de la Hoya Miguel - Nevanlinna Heli - Muranen Taru A - Lespérance Bernard - Spurdle Amanda B - Neuhausen Susan L - Ding Yuan C - Wang Xianshu - Fredericksen Zachary - Pankratz Vernon S - Lindor Noralane M - Peterlongo Paolo - Manoukian Siranoush - Peissel Bernard - Zaffaroni Daniela - Bonanni Bernardo - Bernard Loris - Dolcetti Riccardo - Papi Laura - Ottini Laura - Radice Paolo - Greene Mark H - Loud Jennifer T - Andrulis Irene L - Ozcelik Hilmi - Mulligan Anna U - Glendon Gord - Thomassen Mads - Gerdes Anne-Marie - Jensen Uffe B - Skytte Anne-Bine - Kruse Torben A - Chenevix-Trench Georgia - Couch Fergus J - Simard Jacques - Easton Douglas F - CIMBA - SWE-BRCA - HEBON - EMBRACE - GEMO Collaborators Study - KConFab Investigators
    Breast Cancer Research : BCR | 2012 jan 1 | doi: 10.1186/bcr3121 | ISSN: 1465-542X | Vol. 14 Issue 1
    [PMID: 22348646] IF 5,872

  7. Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).
    Hein Rebecca - Maranian Melanie - Hopper John L - Kapuscinski Miroslaw K - Southey Melissa C - Park Daniel J - Schmidt Marjanka K - Broeks Annegien - Hogervorst Frans B L - Bueno-de-Mesquita H Bas - Bueno-de-Mesquit H Bas - Muir Kenneth R - Lophatananon Artitaya - Rattanamongkongul Suthee - Puttawibul Puttisak - Fasching Peter A - Hein Alexander - Ekici Arif B - Beckmann Matthias W - Fletcher Olivia - Johnson Nichola - dos Santos Silva Isabel - Peto Julian - Sawyer Elinor - Tomlinson Ian - Kerin Michael - Miller Nicola - Marmee Frederick - Schneeweiss Andreas - Sohn Christof - Burwinkel Barbara - Guénel Pascal - Cordina-Duverger Emilie - Menegaux Florence - Truong Thérèse - Bojesen Stig E - Nordestgaard Børge G - Flyger Henrik - Milne Roger L - Perez Jose Ignacio Arias - Zamora M Pilar - Benítez Javier - Anton-Culver Hoda - Ziogas Argyrios - Bernstein Leslie - Clarke Christina A - Brenner Hermann - Müller Heiko - Arndt Volker - Stegmaier Christa - Rahman Nazneen - Seal Sheila - Turnbull Clare - Renwick Anthony - Meindl Alfons - Schott Sarah - Bartram Claus R - Schmutzler Rita K - Brauch Hiltrud - Hamann Ute - Ko Yon-Dschun - GENICA Network - Wang-Gohrke Shan - Dörk Thilo - Schürmann Peter - Karstens Johann H - Hillemanns Peter - Nevanlinna Heli - Heikkinen Tuomas - Aittomäki Kristiina - Blomqvist Carl - Bogdanova Natalia V - Zalutsky Iosif V - Antonenkova Natalia N - Bermisheva Marina - Prokovieva Darya - Farahtdinova Albina - Khusnutdinova Elza - Lindblom Annika - Margolin Sara - Mannermaa Arto - Kataja Vesa - Kosma Veli-Matti - Hartikainen Jaana - Chen Xiaoqing - Beesley Jonathan - KConFab Investigators - AOCS Group - Lambrechts Diether - Zhao Hui - Neven Patrick - Wildiers Hans - Nickels Stefan - Flesch-Janys Dieter - Radice Paolo - Peterlongo Paolo - Manoukian Siranoush - Barile Monica - Couch Fergus J - Olson Janet E - Wang Xianshu - Fredericksen Zachary - Giles Graham G - Baglietto Laura - McLean Catriona A - Severi Gianluca - Offit Kenneth - Robson Mark - Gaudet Mia M - Vijai Joseph - Alnæs Grethe Grenaker - Kristensen Vessela - Børresen-Dale Anne-Lise - John Esther M - Miron Alexander - Winqvist Robert - Pylkäs Katri - Jukkola-Vuorinen Arja - Grip Mervi - Andrulis Irene L - Knight Julia A - Glendon Gord - Mulligan Anna Marie - Figueroa Jonine D - García-Closas Montserrat - Lissowska Jolanta - Sherman Mark E - Hooning Maartje - Martens John W M - Seynaeve Caroline - Collée Margriet - Hall Per - Humpreys Keith - Czene Kamila - Liu Jianjun - Cox Angela - Brock Ian W - Cross Simon S - Reed Malcolm W R - Ahmed Shahana - Ghoussaini Maya - Pharoah Paul D P - Kang Daehee - Yoo Keun-Young - Noh Dong-Young - Jakubowska Anna - Jaworska Katarzyna - Durda Katarzyna - Z?owocka El?bieta - Sangrajrang Suleeporn - Gaborieau Valerie - Brennan Paul - McKay James - Shen Chen-Yang - Yu Jyh-Cherng - Hsu Huan-Ming - Hou Ming-Feng - Orr Nick - Schoemaker Minouk - Ashworth Alan - Swerdlow Anthony - Trentham-Dietz Amy - Newcomb Polly A - Titus Linda - Egan Kathleen M - Chenevix-Trench Georgia - Antoniou Antonis C - Humphreys Manjeet K - Morrison Jonathan - Chang-Claude Jenny - Easton Douglas F - Dunning Alison M
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0042380 | ISSN: 1932-6203 | Vol. 7 Issue 8
    [PMID: 22879957] IF 3,730

  8. Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.
    Sigismund Sara - Confalonieri Stefano - Ciliberto Andrea - Polo Simona - Scita Giorgio - Di Fiore Pier Paolo
    Physiological Reviews | 2012 Jan 1 | doi: 10.1152/physrev.00005.2011 | ISSN: 1522-1210 | Vol. 92 Issue 1
    [PMID: 22298658] IF 30,174

  9. Functional purification of human and mouse mammary stem cells.
    Tosoni Daniela - Di Fiore Pier Paolo - Pece Salvatore
    Methods in Molecular Biology (Clifton, N.J.) | 2012 jan 1 | doi: 10.1007/978-1-61779-980-8_6 | ISSN: 1940-6029 | Vol. 916 Issue nd
    [PMID: 22914933]

  10. Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.
    Mori Silvia - Bernardi Rosa - Laurent Audrey - Resnati Massimo - Crippa Ambra - Gabrieli Arianna - Keough Rebecca - Gonda Thomas J - Blasi Francesco
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0039723 | ISSN: 1932-6203 | Vol. 7 Issue 10
    [PMID: 23056166] IF 3,730

  11. Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.
    Orsenigo Fabrizio - Giampietro Costanza - Ferrari Aldo - Corada Monica - Galaup Ariane - Sigismund Sara - Ristagno Giuseppe - Maddaluno Luigi - Koh Gou Young - Franco Davide - Kurtcuoglu Vartan - Poulikakos Dimos - Baluk Peter - McDonald Donald - Grazia Lampugnani Maria - Dejana Elisabetta
    Nature Communications | 2012 jan 1 | doi: 10.1038/ncomms2199 | ISSN: 2041-1723 | Vol. 3 Issue nd
    [PMID: 23169049] IF 10,015

  12. Reduction of Prep1 levels affects differentiation of normal and malignant B cells and accelerates Myc driven lymphomagenesis.
    Iotti Giorgio - Mejetta Stefania - Modica Livia - Penkov Dmitry - Ponzoni Maurilio - Blasi Francesco
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0048353 | ISSN: 1932-6203 | Vol. 7 Issue 10
    [PMID: 22298658] IF 3,730

  13. Sequencing analysis of SLX4/FANCP gene in Italian familial breast cancer cases.
    Catucci Irene - Colombo Mara - Verderio Paolo - Bernard Loris - Ficarazzi Filomena - Mariette Frederique - Barile Monica - Peissel Bernard - Cattaneo Elisa - Manoukian Siranoush - Radice Paolo - Peterlongo Paolo
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0031038 | ISSN: 1932-6203 | Vol. 7 Issue 2
    [PMID: 22383991] IF 3,730

  14. Signaling-mediated control of ubiquitin ligases in endocytosis.
    Polo Simona
    BMC Biology | 2012 jan 1 | doi: 10.1186/1741-7007-10-25 | ISSN: 1741-7007 | Vol. 10 Issue nd
    [PMID: 22420864] IF 6,531

  15. The endocytic adaptor Eps15 controls marginal zone B cell numbers.
    Adler Thure - Treise Irina - Betsholtz Ingrid Holmberg - Rathkolb Birgit - Busch Dirk H - Wolf Eckhard - Fuchs Helmut - Gailus-Durner Valérie - de Angelis Martin Hrab? - Betsholtz Christer - Casola Stefano - Di Fiore Pier Paolo - Offenhäuser Nina
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0050818 | ISSN: 1932-6203 | Vol. 7 Issue 11
    [PMID: 23226392] IF 3,730

  16. The Kiss-and-Run Model of Intra-Golgi Transport.
    Mironov Alexander A - Beznoussenko Galina V
    International Journal of Molecular Sciences | 2012 jan 1 | doi: 10.3390/ijms13066800 | ISSN: 1422-0067 | Vol. 13 Issue 6
    [PMID: 22837664] IF 2,46

  17. TPT1/ TCTP-regulated pathways in phenotypic reprogramming.
    Amson Robert - Pece Salvatore - Marine Jean-Christophe - Di Fiore Pier Paolo - Telerman Adam
    Trends in Cell Biology | 2013 Jan 1 | doi: 10.1016/j.tcb.2012.10.002 | ISSN: 1879-3088 | Vol. 23 Issue 1
    [PMID: 23122550] IF 11,721

  18. Ve-ptp modulates vascular integrity by promoting adherens junction maturation
    Carra Silvia - Foglia Efrem - Cermenati Solei - Bresciani Erica - Giampietro Costanza - Lora Lamia Carla - Dejana Elisabetta - Beltrame Monica - Cotelli Franco
    PloS one | 2012 jan 1 | doi: 10.1371/journal.pone.0051245 | ISSN: 1932-6203 | Vol. 7 Issue 12
    [PMID: 23251467] IF 3,730

  19. Accelerated endothelial wound healing on microstructured substrates under flow
    Franco Davide - Milde Florian - Klingauf Mirko - Orsenigo Fabrizio - Dejana Elisabetta - Poulikakos Dimos - Cecchini Marco - Koumoutsakos Petros - Ferrari Aldo - Kurtcuoglu Vartan
    Biomaterials | 2013 Feb 1 | doi: 10.1016/j.biomaterials.2012.10.007 | ISSN: 1878-5905 | Vol. 34 Issue 5
    [PMID: 23182348] IF 7,60

  20. BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations
    Fernandez-Rozadilla Ceres - Palles Claire - Carvajal-Carmona Luis - Peterlongo Paolo - Nici Carmela - Veneroni Silvia - Pinheiro Manuela - Teixeira Manuel R - Moreno Victor - Lamas Maria-Jesus - Baiget Montserrat - Lopez-Fernandez LA - Gonzalez Dolors - Brea-Fernandez Alejandro - Clofent Juan - Bujanda Luis - Bessa Xavier - Andreu Montserrat - Xicola Rosa - Llor Xavier - EPICOLON Consortium - Jover Rodrigo - Castells Antoni - Castellvi-Bel Sergi - Carracedo Angel - Tomlinson Ian - Ruiz-Ponte Clara
    Carcinogenesis | 2013 Feb 1 | doi: 10.1093/carcin/bgs357 | ISSN: 1460-2180 | Vol. 34 Issue 0
    [PMID: 23161572] IF 5,635

  21. Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model
    Zhang Baochun - Kracker Sven - Yasuda Tomoharu - Casola Stefano - Vanneman Matthew - Hömig-Hölzel Cornelia - Wang Zhe - Derudder Emmanuel - Li Shuang - Chakraborty Tirtha - Cotter Shane E - Koyama Shohei - Currie Treeve - Freeman Gordon J - Kutok Jeffery L - Rodig Scott J - Dranoff Glenn - Rajewsky Klau
    Cell | 2012 Feb 17 | doi: 10.1016/j.cell.2011.12.031 | ISSN: 1097-4172 | Vol. 148 Issue 4
    [PMID: 22341446] IF 31,95

  22. Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway
    Karras Georgios Ioannis - Fumasoni Marco - Sienski Grzegorz - Vanoli Fabio - Branzei Dana - Jentsch Stefan
    Molecular Cell | 2013 Feb 7 | doi: 10.1016/j.molcel.2012.11.016 | ISSN: 1097-4164 | Vol. 49 Issue 3
    [PMID: 23260657] IF 15,280

  23. Acetylation: a novel link between double-strand break repair and autophagy
    Shubassi Ghadeer - Robert Thomas - Vanoli Fabio - Minucci Saverio - Foiani Marco
    Cancer Research | 2012 Mar 15 | doi: 10.1158/0008-5472.CAN-11-3172 | ISSN: 1538-7445 | Vol. 72 Issue 6
    [PMID: 22422989] IF 8,650

  24. During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks.
    Bustard Denise E - Menolfi Demis - Jeppsson Kristian - Ball Lindsay G - Dewey Sidney Carter - Shirahige Katsuhiko - Sjögren Camilla - Branzei Dana - Cobb Jennifer A
    The Journal of Biological Chemistry | 2012 Mar 30 | doi: 10.1074/jbc.M111.336263 | ISSN: 1083-351X | Vol. 287 Issue 14
    [PMID: 22303010] IF 4,651

  25. Genome-wide association analysis identifies three new breast cancer susceptibility loci.
    Ghoussaini Maya - Fletcher Olivia - Michailidou Kyriaki - Turnbull Clare - Schmidt Marjanka K - Dicks Ed - Dennis Joe - Wang Qin - Humphreys Manjeet K - Luccarini Craig - Baynes Caroline - Conroy Don - Maranian Melanie - Ahmed Shahana - Driver Kristy - Johnson Nichola - Orr Nicholas - dos Santos Silva Isabel - Waisfisz Quinten - Meijers-Heijboer Hanne - Uitterlinden Andre G - Rivadeneira Fernando - Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON) - Hall Per - Czene Kamila - Irwanto Astrid - Liu Jianjun - Nevanlinna Heli - Aittomäki Kristiina - Blomqvist Carl - Meindl Alfons - Schmutzler Rita K - Müller-Myhsok Bertram - Lichtner Peter - Chang-Claude Jenny - Hein Rebecca - Nickels Stefan - Flesch-Janys Dieter - Tsimiklis Helen - Makalic Enes - Schmidt Daniel - Bui Minh - Hopper John L - Apicella Carmel - Park Daniel J - Southey Melissa - Hunter David J - Chanock Stephen J - Broeks Annegien - Verhoef Senno - Hogervorst Frans B L - Fasching Peter A - Lux Michael P - Beckmann Matthias W - Ekici Arif B - Sawyer Elinor - Tomlinson Ian - Kerin Michael - Marme Frederik - Schneeweiss Andreas - Sohn Christof - Burwinkel Barbara - Guénel Pascal - Truong Thérèse - Cordina-Duverger Emilie - Menegaux Florence - Bojesen Stig E - Nordestgaard Børge G - Nielsen Sune F - Flyger Henrik - Milne Roger L - Alonso M Rosario - Gonz ález-Neira Anna - Benítez Javier - Anton-Culver Hoda - Ziogas Argyrios - Bernstein Leslie - Dur Christina Clarke - Brenner Hermann - Müller Heiko - Arndt Volker - Stegmaier Christa - Familial Breast Cancer Study (FBCS) - Justenhoven Christina - Brauch Hiltrud - Brüning Thomas - Gene Environment Interaction of Breast Cancer in Germany (GENICA) Network - Wang-Gohrke Shan - Eilber Ursula - Dörk Thilo - Schürmann Peter - Bremer Michael - Hillemanns Peter - Bogdanova Natalia V - Antonenkova Natalia N - Rogov Yuri I - Karstens Johann H - Bermisheva Marina - Prokofieva Darya - Khusnutdinova Elza - Lindblom Annika - Margolin Sara - Mannermaa Arto - Kataja Vesa - Kosma Veli-Matti - Hartikainen Jaana M - Lambrechts Diether - Yesilyurt Betul T - Floris Giuseppe - Leunen Karin - Manoukian Siranoush - Bonanni Bernardo - Fortuzzi Stefano - Peterlongo Paolo - Couch Fergus J - Wang Xianshu - Stevens Kristen - Lee Adam - Giles Graham G - Baglietto Laura - Severi Gianluca - McLean Catriona - Alnaes Grethe Grenaker - Kristensen Vessela - Børrensen-Dale Anne-Lise - John Esther M - Miron Alexander - Winqvist Robert - Pylkäs Katri - Jukkola-Vuorinen Arja - Kauppila Saila - Andrulis Irene L - Glendon Gord - Mulligan Anna Marie - Devilee Peter - van Asperen Christie J - Tollenaar Rob A E M - Seynaeve Caroline - Figueroa Jonine D - Garcia-Closas Montserrat - Brinton Louise - Lissowska Jolanta - Hooning Maartje J - Hollestelle Antoinette - Oldenburg Rogier A - van den Ouweland Ans M W - Cox Angela - Reed Malcolm W R - Shah Mitul - Jakubowska Ania - Lubinski Jan - Jaworska Katarzyna - Durda Katarzyna - Jones Michael - Schoemaker Minouk - Ashworth Alan - Swerdlow Anthony - Beesley Jonathan - Chen Xiaoqing - KConFab Investigators - Australian Ovarian Cancer Study Group - Muir Kenneth R - Lophatananon Artitaya - Rattanamongkongul Suthee - Chaiwerawattana Arkom - Kang Daehee - Yoo Keun-Young - Noh Dong-Young - Shen Chen-Yang - Yu Jyh-Cherng - Wu Pei-Ei - Hsiung Chia-Ni - Perkins Annie - Swann Ruth - Velentzis Louiza - Eccles Diana M - Tapper Will J - Gerty Susan M - Graham Nikki J - Ponder Bruce A J - Chenevix-Trench Georgia - Pharoah Paul D P - Lathrop Mark - Dunning Alison M - Rahman Nazneen - Peto Julian - Easton Douglas F
    Nature Genetics | 2012 Mar 1 | doi: 10.1038/ng.1049 | ISSN: 1546-1718 | Vol. 44 Issue 3
    [PMID: 22267197] IF 35,209

  26. Highly penetrant melanoma in a zebrafish model is independent of ErbB3b signaling.
    Santoriello Cristina - Anelli Viviana - Alghisi Elisa - Mione Marina
    Pigment Cell & Melanoma Research | 2012 Mar 1 | doi: 10.1111/j.1755-148X.2012.00973.x | ISSN: 1755-148X | Vol. 25 Issue 2
    [PMID: 22248380] IF 5,839

  27. Hormones and AID: balancing immunity and autoimmunity.
    Incorvaia Elisabetta - Sicouri Lara - Petersen-Mahrt Svend K - Schmitz Kerstin-Maike
    Autoimmunity | 2013 Mar 1 | doi: 10.3109/08916934.2012.748752 | ISSN: 1607-842X | Vol. 46 Issue 2
    [PMID: 23181348] IF 2,767

  28. Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells.
    Giampietro Costanza - Taddei Andrea - Corada Monica - Sarra-Ferraris Gian Maria - Alcalay Myriam - Cavallaro Ugo - Orsenigo Fabrizio - Lampugnani Maria Grazia - Dejana Elisabetta
    Blood | 2012 Mar 1 | doi: 10.1182/blood-2011-09-381012 | ISSN: 1528-0020 | Vol. 119 Issue 9
    [PMID: 22246030] IF 9,060

  29. Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcription.
    Bermejo Rodrigo - Lai Mong Sing - Foiani Marco
    Molecular Cell | 2012 Mar 30 | doi: 10.1016/j.molcel.2012.03.001 | ISSN: 1097-4164 | Vol. 45 Issue 6
    [PMID: 22464441] IF 15,280

  30. Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects.
    Pierotti M A - Berrino F - Gariboldi M - Melani C - Mogavero A - Negri T - Pasanisi P - Pilotti S
    Oncogene | 2013 Mar 21 | doi: 10.1038/onc.2012.181 | ISSN: 1476-5594 | Vol. 32 Issue 12
    [PMID: 22665053] IF 7,357

  31. Topoisomerase I poisoning results in PARP-mediated replication fork reversal.
    Ray Chaudhuri Arnab - Hashimoto Yoshitami - Herrador Raquel - Neelsen Kai J - Fachinetti Daniele - Bermejo Rodrigo - Cocito Andrea - Costanzo Vincenzo - Lopes Massimo
    Nature Structural & Molecular Biology | 2012 jan 1 | doi: 10.1038/nsmb.2258 | ISSN: 1545-9985 | Vol. 19 Issue 4
    [PMID: 22388737] IF 11,902

  32. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
    Prahallad Anirudh - Sun Chong - Huang Sidong - Di Nicolantonio Federica - Salazar Ramon - Zecchin Davide - Beijersbergen Roderick L - Bardelli Alberto - Bernards René
    Nature | 2012 Mar 1 | doi: 10.1038/nature10868 | ISSN: 1476-4687 | Vol. 483 Issue 7387
    [PMID: 22281684] IF 38,597

  33. 19p13.1 is a triple-negative-specific breast cancer susceptibility locus.
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  34. A 14-3-3_ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII_ to regulate post-Golgi carrier formation.
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  35. Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
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  36. miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation.
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    Molecular Cancer Research : MCR | 2012 Apr 1 | doi: 10.1158/1541-7786.MCR-11-0342 | ISSN: 1557-3125 | Vol. 10 Issue 4
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  37. Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.
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    Human Mutation | 2012 Apr 1 | doi: 10.1002/humu.22025 | ISSN: 1098-1004 | Vol. 33 Issue 4
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  38. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
    Fumagalli Marzia - Rossiello Francesca - Clerici Michela - Barozzi Sara - Cittaro Davide - Kaplunov Jessica M - Bucci Gabriele - Dobreva Miryana - Matti Valentina - Beausejour Christian M - Herbig Utz - Longhese Maria Pia - d'Adda di Fagagna Fabrizio
    Nature Cell Biology | 2012 Apr 1 | doi: 10.1038/ncb2466 | ISSN: 1476-4679 | Vol. 14 Issue 4
    [PMID: 22426077] IF 20,761

  39. The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
    Laitman Yael - Kuchenbaecker Karoline B - Rantala Johanna - Hogervorst Frans - Peock Susan - Godwin Andrew K - Arason Adalgeir - Kirchhoff Tomas - Offit Kenneth - Isaacs Claudine - Schmutzler Rita K - Wappenschmidt Barbara - Nevanlinna Heli - Chen Xiaoqing - Chenevix-Trench Georgia - Healey Sue - Couch Fergus - Peterlongo Paolo - Radice Paolo - Nathanson Katherine L - Caligo Maria Adelaide - Neuhausen Susan L - Ganz Patricia - Sinilnikova Olga M - McGuffog Lesley - Easton Douglas F - Antoniou Antonis C - Wolf Ido - Friedman Eitan
    Breast Cancer Research and Treatment | 2012 Apr 1 | doi: 10.1007/s10549-011-1938-8 | ISSN: 1573-7217 | Vol. 132 Issue 3
    [PMID: 22212556] IF 4,469

  40. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
    Migliardi Giorgia - Sassi Francesco - Torti Davide - Galimi Francesco - Zanella Eugenia R - Buscarino Michela - Ribero Dario - Muratore Andrea - Massucco Paolo - Pisacane Alberto - Risio Mauro - Capussotti Lorenzo - Marsoni Silvia - Di Nicolantonio Federica - Bardelli Alberto - Comoglio Paolo M - Trusolino Livio - Bertotti Andrea
    Clinical Cancer Research: an Official Journal of the American Association for Cancer Research | 2012 May 1 | doi: 10.1158/1078-0432.CCR-11-2683 | ISSN: 1078-0432 | Vol. 18 Issue 9
    [PMID: 22392911] IF 7,837

  41. Molecular pathways: old drugs define new pathways: non-histone acetylation at the crossroads of the DNA damage response and autophagy.
    Botrugno Oronza Antonietta - Robert Thomas - Vanoli Fabio - Foiani Marco - Minucci Saverio
    Clinical Cancer Research: an Official Journal of the American Association for Cancer Research | 2012 May 1 | doi: 10.1158/1078-0432.CCR-11-0767 | ISSN: 1078-0432 | Vol. 18 Issue 9
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  42. Vascular endothelial-cadherin and vascular stability.
    Dejana Elisabetta - Giampietro Costanza
    Current Opinion in Hematology | 2012 May 1 | doi: 10.1097/MOH.0b013e3283523e1c | ISSN: 1531-7048 | Vol. 19 Issue 3
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  43. Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.
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    British journal of cancer | 2012 Jun 5 | doi: 10.1038/bjc.2012.160 | ISSN: 1532-1827 | Vol. 106 Issue 12
    [PMID: 22669161] IF 5,082

  44. Dna2 offers support for stalled forks.
    Lai Mong Sing - Foiani Marco
    Cell | 2012 Jun 8 | doi: 10.1016/j.cell.2012.05.021 | ISSN: 1097-4172 | Vol. 149 Issue 6
    [PMID: 22682239] IF 31,957

  45. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
    Misale Sandra - Yaeger Rona - Hobor Sebastijan - Scala Elisa - Janakiraman Manickam - Liska David - Valtorta Emanuele - Schiavo Roberta - Buscarino Michela - Siravegna Giulia - Bencardino Katia - Cercek Andrea - Chen Chin-Tung - Veronese Silvio - Zanon Carlo - Sartore-Bianchi Andrea - Gambacorta Marcello - Gallicchio Margherita - Vakiani Efsevia - Boscaro Valentina - Medico Enzo - Weiser Martin - Siena Salvatore - Di Nicolantonio Federica - Solit David - Bardelli Alberto
    Nature | 2012 Jun 28 | doi: 10.1038/nature11156 | ISSN: 1476-4687 | Vol. 486 Issue 7404
    [PMID: 22722830] IF 38,597

  46. EuFishBioMed (COST Action BM0804): a European network to promote the use of small fishes in biomedical research.
    Strähle Uwe - Bally-Cuif Laure - Kelsh Robert - Beis Dimitris - Mione Marina - Panula Pertti - Figueras Antonio - Gothilf Yoav - Brösamle Christian - Geisler Robert - Knedlitschek Gudrun
    Zebrafish | 2012 Jun 1 | doi: 10.1089/zeb.2012.0742 | ISSN: 1557-8542 | Vol. 9 Issue 2
    [PMID: 22537014] IF 2,883

  47. Is cellular senescence an example of antagonistic pleiotropy?
    Giaimo Stefano - d'Adda di Fagagna Fabrizio
    Aging Cell | 2012 Jun 1 | doi: 10.1111/j.1474-9726.2012.00807.x | ISSN: 1474-9726 | Vol. 11 Issue 3
    [PMID: 22329645] IF 5,705

  48. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions.
    Suram Anitha - Kaplunov Jessica - Patel Priyanka L - Ruan Haihe - Cerutti Aurora - Boccardi Virginia - Fumagalli Marzia - Di Micco Raffaella - Mirani Neena - Gurung Resham Lal - Hande Manoor Prakash - d'Adda di Fagagna Fabrizio - Herbig Utz
    The EMBO Journal | 2012 Jun 29 | doi: 10.1038/emboj.2012.132 | ISSN: 1460-2075 | Vol. 31 Issue 13
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  49. Protecting normal cells from the cytotoxicity of chemotherapy.
    Cheok Chit Fang
    Cell Cycle (Georgetown, Tex.) | 2012 Jun 15 | doi: 10.4161/cc.20961 | ISSN: 1551-4005 | Vol. 11 Issue 12
    [PMID: 22684296] IF 5,243

  50. The SNP rs895819 in miR-27a is not associated with familial breast cancer risk in Italians.
    Catucci Irene - Verderio Paolo - Pizzamiglio Sara - Bernard Loris - Dall'olio Valentina - Sardella Domenico - Ravagnani Fernando - Galastri Laura - Barile Monica - Peissel Bernard - Zaffaroni Daniela - Manoukian Siranoush - Radice Paolo - Peterlongo Paolo
    Breast Cancer Research and Treatment | 2012 Jun 1 | doi: 10.1007/s10549-012-2011-y | ISSN: 1573-7217 | Vol. 133 Issue 2
    [PMID: 22415478] IF 4,469

  51. 11q13 is a susceptibility locus for hormone receptor positive breast cancer.
    Lambrechts Diether - Truong Therese - Justenhoven Christina - Humphreys Manjeet K - Wang Jean - Hopper John L - Dite Gillian S - Apicella Carmel - Southey Melissa C - Schmidt Marjanka K - Broeks Annegien - Cornelissen Sten - van Hien Richard - Sawyer Elinor - Tomlinson Ian - Kerin Michael - Miller Nicola - Milne Roger L - Zamora M Pilar - Pérez José Ignacio Arias - Benítez Javier - Hamann Ute - Ko Yon-Dschun - Brüning Thomas - GENICA Network - Chang-Claude Jenny - Eilber Ursel - Hein Rebecca - Nickels Stefan - Flesch-Janys Dieter - Wang-Gohrke Shan - John Esther M - Miron Alexander - Winqvist Robert - Pylkäs Katri - Jukkola-Vuorinen Arja - Grip Mervi - Chenevix-Trench Georgia - Beesley Jonathan - Chen Xiaoqing - Investigators KConFab - Australian Ovarian Cancer Study Group - Menegaux Florence - Cordina-Duverger Emilie - Shen Chen-Yang - Yu Jyh-Cherng - Wu Pei-Ei - Hou Ming-Feng - Andrulis Irene L - Selander Teresa - Glendon Gord - Mulligan Anna Marie - Anton-Culver Hoda - Ziogas Argyrios - Muir Kenneth R - Lophatananon Artitaya - Rattanamongkongul Suthee - Puttawibul Puttisak - Jones Michael - Orr Nicholas - Ashworth Alan - Swerdlow Anthony - Severi Gianluca - Baglietto Laura - Giles Graham - Southey Melissa - Marmé Federik - Schneeweiss Andreas - Sohn Christof - Burwinkel Barbara - Yesilyurt Betul T - Neven Patrick - Paridaens Robert - Wildiers Hans - Brenner Hermann - Müller Heiko - Arndt Volker - Stegmaier Christa - Meindl Alfons - Schott Sarah - Bartram Claus R - Schmutzler Rita K - Cox Angela - Brock Ian W - Elliott Graeme - Cross Simon S - Fasching Peter A - Schulz-Wendtland Ruediger - Ekici Arif B - Beckmann Matthias W - Fletcher Olivia - Johnson Nichola - Silva Isabel Dos Santos - Peto Julian - Nevanlinna Heli - Muranen Taru A - Aittomäki Kristiina - Blomqvist Carl - Dörk Thilo - Schürmann Peter - Bremer Michael - Hillemanns Peter - Bogdanova Natalia V - Antonenkova Natalia N - Rogov Yuri I - Karstens Johann H - Khusnutdinova Elza - Bermisheva Marina - Prokofieva Darya - Gancev Shamil - Jakubowska Anna - Lubinski Jan - Jaworska Katarzyna - Durda Katarzyna - Nordestgaard Børge G - Bojesen Stig E - Lanng Charlotte - Mannermaa Arto - Kataja Vesa - Kosma Veli-Matti - Hartikainen Jaana M - Radice Paolo - Peterlongo Paolo - Manoukian Siranoush - Bernard Loris - Couch Fergus J - Olson Janet E - Wang Xianshu - Fredericksen Zachary - Alnaes Grethe Grenaker - Kristensen Vessela - Børresen-Dale Anne-Lise - Devilee Peter - Tollenaar Robert A E M - Seynaeve Caroline M - Hooning Maartje J - García-Closas Montserrat - Chanock Stephen J - Lissowska Jolanta - Sherman Mark E - Hall Per - Liu Jianjun - Czene Kamila - Kang Daehee - Yoo Keun-Young - Noh Dong-Young - Lindblom Annika - Margolin Sara - Dunning Alison M - Pharoah Paul D P - Easton Douglas F - Guénel Pascal - Brauch Hiltrud
    Human Mutation | 2012 Jul 1 | doi: 10.1002/humu.22089 | ISSN: 1098-1004 | Vol. 33 Issue 7
    [PMID: 22461340] IF 5,213

  52. A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase.
    Gatti Marco - Pinato Sabrina - Maspero Elena - Soffientini Paolo - Polo Simona - Penengo Lorenza
    Cell Cycle (Georgetown, Tex.) | 2012 Jul 1 | doi: 10.4161/cc.20919 | ISSN: 1551-4005 | Vol. 11 Issue 13
    [PMID: 22713238] IF 5,243

  53. Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy.
    Ottini Laura - Silvestri Valentina - Rizzolo Piera - Falchetti Mario - Zanna Ines - Saieva Calogero - Masala Giovanna - Bianchi Simonetta - Manoukian Siranoush - Barile Monica - Peterlongo Paolo - Varesco Liliana - Tommasi Stefania - Russo Antonio - Giannini Giuseppe - Cortesi Laura - Viel Alessandra - Montagna Marco - Radice Paolo - Palli Domenico
    Breast Cancer Research and Treatment | 2012 Jul 1 | doi: 10.1007/s10549-012-2062-0 | ISSN: 1573-7217 | Vol. 134 Issue 1
    [PMID: 22527108] IF 4,469

  54. Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation.
    Schneider Leonid - d'Adda di Fagagna Fabrizio
    Nucleic Acids Research | 2012 Jul 1 | doi: 10.1093/nar/gks207 | ISSN: 1362-4962 | Vol. 40 Issue 12
    [PMID: 22379135] IF 8,278

  55. A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.
    Ding Yuan C - McGuffog Lesley - Healey Sue - Friedman Eitan - Laitman Yael - Paluch-Shimon Shani- - Kaufman Bella - SWE-BRCA - Liljegren Annelie - Lindblom Annika - Olsson Håkan - Kristoffersson Ulf - Stenmark-Askmalm Marie - Melin Beatrice - Domchek Susan M - Nathanson Katherine L - Rebbeck Timothy R - Jakubowska Anna - Lubinski Jan - Jaworska Katarzyna - Durda Katarzyna - Gronwald Jacek - Huzarski Tomasz - Cybulski Cezary - Byrski Tomasz - Osorio Ana - Cajal Teresa Ramóny - Stavropoulou Alexandra V - Benítez Javier - Hamann Ute - HEBON - Rookus Matti - Aalfs Cora M - de Lange Judith L - Meijers-Heijboer Hanne E J - Oosterwijk Jan C - van Asperen Christi J - Gómez García Encarna B - Hoogerbrugge Nicoline - Jager Agnes - van der Luijt Rob B - EMBRACE - Easton Douglas F - Peock Susan - Frost Debra - Ellis Steve D - Platte Radka - Fineberg Elena - Evans D Gareth - Lalloo Fiona - Izatt Louise - Eeles Ros - Adlard Julian - Davidson Rosemarie - Eccles Diana - Cole Trevor - Cook Jackie - Brewer Carole - Tischkowitz Marc - Godwin Andrew K - Pathak Harsh - GEMO Study Collaborators - Stoppa-Lyonnet Dominique - Sinilnikova Olga M - Mazoyer Sylvie - Barjhoux Laure - Léoné Mélanie - Gauthier-Villars Marion - Caux-Moncoutier Virginie - de Pauw Antoine - Hardouin Agnès - Berthet Pascaline - Dreyfus Hélène - Ferrer Sandra Fert - Collonge-Rame Marie-Agnès - Sokolowska Johanna - Buys Saundra - Daly Mary - Miron Alex - Terry Mary Beth - Chung Wendy - John Esther M - Southey Melissa - Goldgar David - Singer Christian F - Tea Muy-Kheng Maria - Gschwantler-Kaulich Daphne - Fink-Retter Anneliese - Hansen Thomas V O - Ejlertsen Bent - Johannsson Oskar T - Offit Kenneth - Sarrel Kara - Gaudet Mia M - Vijai Joseph - Robson Mark - Piedmonte Marion R - Andrews Lesley - Cohn David - DeMars Leslie R - DiSilvestro Paul - Rodriguez Gustavo - Toland Amanda Ewart - Montagna Marco - Agata Simona - Imyanitov Evgeny - Isaacs Claudine - Janavicius Ramunas - Lazaro Conxi - Blanco Ignacio - Ramus Susan J - Sucheston Lara - Karlan Beth Y - Gross Jenny - Ganz Patricia A - Beattie Mary S - Schmutzler Rita K - Wappenschmidt Barbara - Meindl Alfons - Arnold Norbert - Niederacher Dieter - Preisler-Adams Sabine - Gadzicki Dorotehea - Varon-Mateeva Raymonda - Deissler Helmut - Gehrig Andrea - Sutter Christian - Kast Karin - Nevanlinna Heli - Aittomäki Kristiina - Simard Jacques - KConFab Investigators - Spurdle Amanda B - Beesley Jonathan - Chen Xiaoqing - Tomlinson Gail E - Weitzel Jeffrey - Garber Judy E - Olopade Olufunmilayo I - Rubinstein Wendy S - Tung Nadine - Blum Joanne L - Narod Steven A - Brummel Sean - Gillen Daniel L - Lindor Noralane - Fredericksen Zachary - Pankratz Vernon S - Couch Fergus J - Radice Paolo - Peterlongo Paolo - Greene Mark H - Loud Jennifer T - Mai Phuong L - Andrulis Irene L - Glendon Gord - Ozcelik Hilmi - OCGN - Gerdes Anne-Marie - Thomassen Mads - Jensen Uffe Birk - Skytte Anne-Bine - Caligo Maria A - Lee Andrew - Chenevix-Trench Georgia - Antoniou Antonis C - Neuhausen Susan L - Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
    Cancer Epidemiology, Biomarkers & Prevention | 2012 Aug 1 | doi: 10.1158/1055-9965.EPI-12-0229 | ISSN: 1538-7755 | Vol. 21 Issue 8
    [PMID: 22729394] IF 4,559

  56. AIDing the immune system-DIAbolic in cancer.
    Schmitz Kerstin-Maike - Petersen-Mahrt Svend K
    Seminars in Immunology | 2012 Aug 1 | doi: 10.1016/j.smim.2012.07.001 | ISSN: 1096-3618 | Vol. 24 Issue 4
    [PMID: 22841422] IF 5,926

  57. Publishing: Alarming shift away from sharing results.
    Boniolo Giovanni - Vaccari Thomas
    Nature | 2012 Aug 9 | doi: 10.1038/488157d | ISSN: 1476-4687 | Vol. 488 Issue 7410
    [PMID: 22874955] IF 38,597

  58. Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1.
    Daee Danielle L - Ferrari Elisa - Longerich Simonne - Zheng Xiao-feng - Xue Xiaoyu - Branzei Dana - Sung Patrick - Myung Kyungjae
    The Journal of Biological Chemistry | 2012 Aug 3 | doi: 10.1074/jbc.M112.369918 | ISSN: 1083-351X | Vol. 287 Issue 32
    [PMID: 22696213] IF 4,651

  59. Site-specific DICER and DROSHA RNA products control the DNA-damage response.
    Francia Sofia - Michelini Flavia - Saxena Alka - Tang Dave - de Hoon Michiel - Anelli Viviana - Mione Marina - Carninci Piero - d'Adda di Fagagna Fabrizio
    Nature | 2012 Aug 9 | doi: 10.1038/nature11179 | ISSN: 1476-4687 | Vol. 488 Issue 7410
    [PMID: 22722852] IF 38,597

  60. The young and happy marriage of membrane traffic and cell polarity.
    Thompson Barry J - Perez Franck - Vaccari Thomas
    EMBO Reports | 2012 Aug 1 | doi: 10.1038/embor.2012.98 | ISSN: 1469-3178 | Vol. 13 Issue 8
    [PMID: 22777496] IF 7,189

  61. Germline mutations in BRIP1 and PALB2 in Jewish high cancer risk families.
    Catucci Irene - Milgrom Roni - Kushnir Anya - Laitman Yael - Paluch-Shimon Shani - Volorio Sara - Ficarazzi Filomena - Bernard Loris - Radice Paolo - Friedman Eitan - Peterlongo Paolo
    Familial Cancer | 2012 Sep 1 | doi: 10.1007/s10689-012-9540-8 | ISSN: 1573-7292 | Vol. 11 Issue 3
    [PMID: 22692731] IF 1,935

  62. Investigation of in vitro cytotoxicity of the redox state of ionic iron in neuroblastoma cells.
    Singh Ajay Vikram - Vyas Varun - Montani Erica - Maontani Erica - Cartelli Daniele - Parazzoli Dario - Oldani Amanda - Zeri Giulia - Orioli Elisa - Gemmati Donato - Zamboni Paolo
    Journal of Neurosciences in Rural Practice | 2012 Sep 1 | doi: 10.4103/0976-3147.102611 | ISSN: 0976-3155 | Vol. 3 Issue 3
    [PMID: 23188983] IF 6,908

  63. Preserving the genome by regulating chromatin association with the nuclear envelope.
    Bermejo Rodrigo - Kumar Amit - Foiani Marco
    Trends in Cell Biology | 2012 Sep 1 | doi: 10.1016/j.tcb.2012.05.007 | ISSN: 1879-3088 | Vol. 22 Issue 9
    [PMID: 22771046] IF 11,721

  64. Sedlin controls the ER export of procollagen by regulating the Sar1 cycle.
    Venditti Rossella - Scanu Tiziana - Santoro Michele - Di Tullio Giuseppe - Spaar Alexander - Gaibisso Renato - Beznoussenko Galina V - Mironov Alexander A - Mironov Alexander - Zelante Leopoldo - Piemontese Maria Rosaria - Notarangelo Angelo - Malhotra Vivek - Vertel Barbara M - Wilson Cathal - De Matteis Maria Antonietta
    Science (New York, N.Y.) | 2012 Sep 28 | doi: 10.1126/science.1224947 | ISSN: 1095-9203 | Vol. 337 Issue 0
    [PMID: 23019651] IF 31,027

  65. The role of genetic breast cancer susceptibility variants as prognostic factors.
    Fasching Peter A - Pharoah Paul D P - Cox Angela - Nevanlinna Heli - Bojesen Stig E - Karn Thomas - Broeks Annegien - van Leeuwen Flora E - van't Veer Laura J - Udo Renate - Dunning Alison M - Greco Dario - Aittomäki Kristiina - Blomqvist Carl - Shah Mitul - Nordestgaard Børge G - Flyger Henrik - Hopper John L - Southey Melissa C - Apicella Carmel - Garcia-Closas Montserrat - Sherman Mark - Lissowska Jolanta - Seynaeve Caroline - Huijts Petra E A - Tollenaar Rob A E M - Ziogas Argyrios - Ekici Arif B - Rauh Claudia - Mannermaa Arto - Kataja Vesa - Kosma Veli-Matti - Hartikainen Jaana M - Andrulis Irene L - Ozcelik Hilmi - Mulligan Anna-Marie - Glendon Gord - Hall Per - Czene Kamila - Liu Jianjun - Chang-Claude Jenny - Wang-Gohrke Shan - Eilber Ursula - Nickels Stefan - Dörk Thilo - Schiekel Maria - Bremer Michael - Park-Simon Tjoung-Won - Giles Graham G - Severi Gianluca - Baglietto Laura - Hooning Maartje J - Martens John W M - Jager Agnes - Kriege Mieke - Lindblom Annika - Margolin Sara - Couch Fergus J - Stevens Kristen N - Olson Janet E - Kosel Matthew - Cross Simon S - Balasubramanian Sabapathy P - Reed Malcolm W R - Miron Alexander - John Esther M - Winqvist Robert - Pylkäs Katri - Jukkola-Vuorinen Arja - Kauppila Saila - Burwinkel Barbara - Marme Frederik - Schneeweiss Andreas - Sohn Christof - Chenevix-Trench Georgia - KConFab Investigators - Lambrechts Diether - Dieudonne Anne-Sophie - Hatse Sigrid - van Limbergen Erik - Benitez Javier - Milne Roger L - Zamora M Pilar - Pérez José Ignacio Arias - Bonanni Bernardo - Peissel Bernard - Loris Bernard - Peterlongo Paolo - Rajaraman Preetha - Schonfeld Sara J - Anton-Culver Hoda - Devilee Peter - Beckmann Matthias W - Slamon Dennis J - Phillips Kelly-Anne - Figueroa Jonine D - Humphreys Manjeet K - Easton Douglas F - Schmidt Marjanka K
    Human Molecular Genetics | 2012 Sep 1 | doi: 10.1093/hmg/dds159 | ISSN: 1460-2083 | Vol. 21 Issue 17
    [PMID: 22532573] IF 7,692

  66. The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment.
    Era Saho - Abe Takuya - Arakawa Hiroshi - Kobayashi Shunsuke - Szakal Barnabas - Yoshikawa Yusuke - Motegi Akira - Takeda Shunichi - Branzei Dana
    Biochemical and Biophysical Research Communication | 2012 Sep 28 | doi: 10.1016/j.bbrc.2012.08.066 | ISSN: 1090-2104 | Vol. 426 Issue 3
    [PMID: 22943854] IF 2,406

  67. 9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
    Warren Helen - Dudbridge Frank - Fletcher Olivia - Orr Nick - Johnson Nichola - Hopper John L - Apicella Carmel - Southey Melissa C - Mahmoodi Maryam - Schmidt Marjanka K - Broeks Annegien - Cornelissen Sten - Braaf Linda M - Muir Kenneth R - Lophatananon Artitaya - Chaiwerawattana Arkom - Wiangnon Surapon - Fasching Peter A - Beckmann Matthias W - Ekici Arif B - Schulz-Wendtland Ruediger - Sawyer Elinor J - Tomlinson Ian - Kerin Michael - Burwinkel Barbara - Marme Frederik - Schneeweiss Andreas - Sohn Christof - Guénel Pascal - Truong Thérèse - Laurent-Puig Pierre - Mulot Claire - Bojesen Stig E - Nielsen Sune F - Flyger Henrik - Nordestgaard Børge G - Milne Roger L - Benítez Javier - Arias-Pérez José-Ignacio - Zamora M Pilar - Anton-Culver Hoda - Ziogas Argyrios - Bernstein Leslie - Dur Christina Clarke - Brenner Hermann - Müller Heiko - Arndt Volker - Langheinz Anne - Meindl Alfons - Golatta Michael - Bartram Claus R - Schmutzler Rita K - Brauch Hiltrud - Justenhoven Christina - Brüning Thomas - GENICA Network - Chang-Claude Jenny - Wang-Gohrke Shan - Eilber Ursula - Dörk Thilo - Schürmann Peter - Bremer Michael - Hillemanns Peter - Nevanlinna Heli - Muranen Taru A - Aittomäki Kristiina - Blomqvist Carl - Bogdanova Natalia - Antonenkova Natalia - Rogov Yuriy - Bermisheva Marina - Prokofyeva Darya - Zinnatullina Guzel - Khusnutdinova Elza - Lindblom Annika - Margolin Sara - Mannermaa Arto - Kosma Veli-Matti - Hartikainen Jaana M - Kataja Vesa - Chenevix-Trench Georgia - Beesley Jonathan - Chen Xiaoqing - KConFab Investigators - Australian Ovarian Cancer Study Group - Lambrechts Diether - Smeets Ann - Paridaens Robert - Weltens Caroline - Flesch-Janys Dieter - Buck Katharina - Behrens Sabine - Peterlongo Paolo - Bernard Loris - Manoukian Siranoush - Radice Paolo - Couch Fergus J - Vachon Celine - Wang Xianshu - Olson Janet - Giles Graham - Baglietto Laura - McLean Cariona A - Severi Gianluca - John Esther M - Miron Alexander - Winqvist Robert - Pylkäs Katri - Jukkola-Vuorinen Arja - Grip Mervi - Andrulis Irene L - Knight Julia A - Mulligan Anna Marie - Weerasooriya Nayana - Devilee Peter - Tollenaar Robert A E M - Martens John W M - Seynaeve Caroline M - Hooning Maartje J - Hollestelle Antoinette - Jager Agnes - Tilanus-Linthorst Madeleine M A - Hall Per - Czene Kamila - Liu Jianjun - Li Jingmei - Cox Angela - Cross Simon S - Brock Ian W - Reed Malcolm W R - Pharoah Paul - Blows Fiona M - Dunning Alison M - Ghoussaini Maya - Ashworth Alan - Swerdlow Anthony - Jones Michael - Schoemaker Minouk - Easton Douglas F - Humphreys Manjeet - Wang Qin - Peto Julian - dos-Santos-Silva Isabel
    Cancer Epidemiology, Biomarkers & Prevention | 2012 Oct 1 | doi: 10.1158/1055-9965.EPI-12-0526 | ISSN: 1538-7755 | Vol. 21 Issue 10
    [PMID: 22859399] IF 4,559

  68. A role for the RNA pol II-associated PAF complex in AID-induced immune diversification.
    Willmann Katharina L - Milosevic Sara - Pauklin Siim - Schmitz Kerstin-Maike - Rangam Gopinath - Simon Maria T - Maslen Sarah - Skehel Mark - Robert Isabelle - Heyer Vincent - Schiavo Ebe - Reina-San-Martin Bernardo - Petersen-Mahrt Svend K
    The Journal of Experimental Medicine | 2012 Oct 22 | doi: 10.1084/jem.20112145 | ISSN: 1540-9538 | Vol. 209 Issue 11
    [PMID: 23008333] IF 13,214

  69. Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer.
    Sulli Gabriele - Di Micco Raffaella - d'Adda di Fagagna Fabrizio
    The Journal of Cell Biology | 2012 Oct 1 | doi: 10.1083/jcb.201206033 | ISSN: 1540-8140 | Vol. 199 Issue 1
    [PMID: 23027903] IF 10,822

  70. Differentiation-associated microRNAs antagonize the Rb-E2F pathway to restrict proliferation.
    Marzi Matteo J - Puggioni Eleonora M R - Dall'olio Valentina - Bucci Gabriele - Bernard Loris - Bianchi Fabrizio - Crescenzi Marco - Di Fiore Pier Paolo - Nicassio Francesco

    [PMID: 23122550] IF

  71. LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53.
    Crespi Arianna - Ferrari Ilaria - Lonati Paola - Disanza Andrea - Fornasari Diego - Scita Giorgio - Padovano Valeria - Pietrini Grazia
    Journal of Cell Science | 2012 Oct 1 | doi: 10.1242/jcs.106484 | ISSN: 1477-9137 | Vol. 125 Issue Pt 19
    [PMID: 22767515] IF 5,877

  72. Rare variants in XRCC2 as breast cancer susceptibility alleles.
    Hilbers Florentine S - Wijnen Juul T - Hoogerbrugge Nicoline - Oosterwijk Jan C - Collee Margriet J - Peterlongo Paolo - Radice Paolo - Manoukian Siranoush - Feroce Irene - Capra Fabio - Couch Fergus J - Wang Xianshu - Guidugli Lucia - Offit Kenneth - Shah Sohela - Campbell Ian G - Thompson Ella R - James Paul A - Trainer Alison H - Gracia Javier - Benitez Javier - van Asperen Christi J - Devilee Peter
    Journal of Medical Genetics | 2012 Oct 1 | doi: 10.1136/jmedgenet-2012-101191 | ISSN: 1468-6244 | Vol. 49 Issue 10
    [PMID: 23054243] IF 5,703

  73. Role of the Mad2 dimerization interface in the spindle assembly checkpoint independent of kinetochores.
    Mariani Luca - Chiroli Elena - Nezi Luigi - Müller Heiko - Piatti Simonetta - Musacchio Andrea - Ciliberto Andrea
    Current Biology : CB | 2012 Oct 23 | doi: 10.1016/j.cub.2012.08.028 | ISSN: 1879-0445 | Vol. 22 Issue 20
    [PMID: 23000150] IF 9,494

  74. Seeking synergy in p53 transcriptional activation for cancer therapy.
    Cheok Chit Fang - Lane David P
    Discovery Medicine | 2012 Oct 1 | doi: | ISSN: 1944-7930 | Vol. 14 Issue 0
    [PMID: 23114582] IF 2,965

  75. A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
    Bertotti Andrea - Migliardi Giorgia - Galimi Francesco - Sassi Francesco - Torti Davide - Isella Claudio - Corà Davide - Di Nicolantonio Federica - Buscarino Michela - Petti Consalvo - Ribero Dario - Russolillo Nadia - Muratore Andrea - Massucco Paolo - Pisacane Alberto - Molinaro Luca - Valtorta Emanuele - Sartore-Bianchi Andrea - Risio Mauro - Capussotti Lorenzo - Gambacorta Marcello - Siena Salvatore - Medico Enzo - Sapino Anna - Marsoni Silvia - Comoglio Paolo M - Bardelli Alberto - Trusolino Livio
    Cancer Discovery | 2011 Nov 1 | doi: 10.1158/2159-8290.CD-11-0109 | ISSN: 2159-8290 | Vol. 1 Issue 0
    [PMID: 22586653] IF 10,143

  76. Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.
    Vermezovic J - Stergiou L - Hengartner M O - d'Adda di Fagagna Fabrizio
    Cell Death and Differentiation | 2012 Nov 1 | doi: 10.1038/cdd.2012.69 | ISSN: 1476-5403 | Vol. 19 Issue 11
    [PMID: 22705849] IF 8,371

  77. Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes.
    Alzu Amaya - Bermejo Rodrigo - Begnis Martina - Lucca Chiara - Piccini Daniele - Carotenuto Walter - Saponaro Marco - Brambati Alessandra - Cocito Andrea - Foiani Marco - Liberi Giordano
    Cell | 2012 Nov 9 | doi: 10.1016/j.cell.2012.09.041 | ISSN: 1097-4172 | Vol. 151 Issue 4
    [PMID: 23141540] IF 31,957

  78. The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival.
    Burgold Thomas - Voituron Nicolas - Caganova Marieta - Tripathi Prem Prakash - Menuet Clement - Tusi Betsabeh Khoramian - Spreafico Fabio - Bévengut Michelle - Gestreau Christian - Buontempo Serena - Simeone Antonio - Kruidenier Laurens - Natoli Gioacchino - Casola Stefano - Hilaire Gérard - Testa Giuseppe
    Cell Reports | 2012 Nov 29 | doi: 10.1016/j.celrep.2012.09.013 | ISSN: 2211-1247 | Vol. 2 Issue 5
    [PMID: 23103168]

  79. The spindle-assembly checkpoint and the beauty of self-destruction.
    Musacchio Andrea - Ciliberto Andrea
    Nature Structural & Molecular Biology | 2012 Nov 1 | doi: 10.1038/nsmb.2429 | ISSN: 1545-9985 | Vol. 19 Issue 11
    [PMID: 23132380] IF 11,902

  80. The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.
    Wiedmann Romina M - von Schwarzenberg Karin - Palamidessi Andrea - Schreiner Laura - Kubisch Rebekka - Liebl Johanna - Schempp Christina - Trauner Dirk - Vereb Gyorgy - Zahler Stefan - Wagner Ernst - Müller Rolf - Scita Giorgio - Vollmar Angelika M
    Cancer Research | 2012 Nov 15 | doi: 10.1158/0008-5472.CAN-12-1772 | ISSN: 1538-7445 | Vol. 72 Issue 22
    [PMID: 22986742] IF 8,650

  81. Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site.
    Brewster Brooke L - Rossiello Francesca - French Juliet D - Edwards Stacey L - Wong Ming - Wronski Ania - Whiley Phillip - Waddell Nic - Chen Xiaowei - Bove Betsy - KConFab - Hopper John L - John Esther M - Andrulis Irene - Daly Mary - Volorio Sara - Bernard Loris - Peissel Bernard - Manoukian Siranoush - Barile Monica - Pizzamiglio Sara - Verderio Paolo - Spurdle Amanda B - Radice Paolo - Godwin Andrew K - Southey Melissa C - Brown Melissa A - Peterlongo Paolo
    Human Mutation | 2012 Dec 1 | doi: 10.1002/humu.22159 | ISSN: 1098-1004 | Vol. 33 Issue 12
    [PMID: 22753153] IF 5,213



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