Publications 2020
last update March 2021
- Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma
Castellan M., Guarnieri A., Fujimura A., Zanconato F., Battilana G., Panciera T., Sladitschek H.L., Contessotto P., Citron A., Grilli A., Romano O., Bicciato S., Fassan M., Porcù E., Rosato A., Cordenonsi M., Piccolo S.
Nat Cancer . 2021 Feb;2(2):174-188. doi: 10.1038/s43018-020-00150-z. Epub 2020 Dec 7.
[33644767] - Cellular senescence in ageing: from mechanisms to therapeutic opportunities
Di Micco R., Krizhanovsky V., Baker D., d’Adda di Fagagna F.
Nat Rev Mol Cell Biol . 2021 Feb;22(2):75-95. doi: 10.1038/s41580-020-00314-w. Epub 2020 Dec 16.
[33328614] - Cooperative effects on the compaction of DNA fragments by the nucleoid protein H-NS and the crowding agent PEG probed by Magnetic Tweezers
Cristofalo M., Marrano C.A., Salerno D., Corti R., Cassina V., Mammola A., Gherardi M., Sclavi B., Cosentino Lagomarsino M., Mantegazza F.
Biochim Biophys Acta Gen Subj. 2020 Dec;1864(12):129725. doi: 10.1016/j.bbagen.2020.129725. Epub 2020 Sep 3.
[32891648] - EGFR as a stable marker of prostate cancer dissemination to bones
Nastały P., Stoupiec S., Popęda M., Smentoch J., Schlomm T., Morrissey C., Żaczek A.J., Beyer B., Tennstedt P., Graefen M., Eltze E., Maiuri P., Semjonow A., Pantel K., Brandt B., Bednarz-Knoll N.
Br J Cancer. 2020 Dec;123(12):1767-1774. doi: 10.1038/s41416-020-01052-8. Epub 2020 Sep 9.
[32901137] - Ouabain and digoxin activate the proteasome and the degradation of the erα in cells modeling primary and metastatic breast cancer
Busonero C., Leone S., Bianchi F., Maspero E., Fiocchetti M., Palumbo O., Cipolletti M., Bartoloni S., Acconcia F.
Cancers (Basel). 2020 Dec 19;12(12):3840. doi: 10.3390/cancers12123840.
[33352737] - Breast cancer organoids model patient‐specific response to drug treatment
Campaner E., Zannini A., Santorsola M., Bonazza D., Bottin C., Cancila V., Tripodo C., Bortul M., Zanconati F., Schoeftner S., Del Sal G.
Cancers (Basel). 2020 Dec 21;12(12):3869. doi: 10.3390/cancers12123869.
[33371412] - Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s disease
Milanese C., Gabriels S., Barnhoorn S., Cerri S., Ulusoy A., Gornati S.V., Wallace D.F., Blandini F., Di Monte D.A., Subramaniam V.N., Mastroberardino P.G.
Cell Death Differ. 2020 Dec 16. doi: 10.1038/s41418-020-00698-4. Online ahead of print.
[33323945] - Hormone Receptor Loss in Breast Cancer: Molecular Mechanisms, Clinical Settings, and Therapeutic Implications
Zattarin E., Leporati R., Ligorio F., Lobefaro R., Vingiani A., Pruneri G., Vernieri C.
Cells. 2020 Dec 9;9(12):2644. doi: 10.3390/cells9122644.
[33316954] - Long-term Clinical Outcome of Trastuzumab and Lapatinib for HER2-positive Metastatic Colorectal Cancer
Tosi F., Sartore-Bianchi A., Lonardi S., Amatu A., Leone F., Ghezzi S., Martino C., Bencardino K., Bonazzina E., Bergamo F., Fenocchio E., Martinelli E., Troiani T., Siravegna G., Mauri G., Torri V., Marrapese G., Valtorta E., Cassingena A., Cappello G., Bonoldi E., Vanzulli A., Regge D., Ciardiello F., Zagonel V., Bardelli A., Trusolino L., Marsoni S., Siena S.
Clin Colorectal Cancer. 2020 Dec;19(4):256-262.e2. doi: 10.1016/j.clcc.2020.06.009. Epub 2020 Jun 27.
[32919890] - Periodic and Intermittent Fasting in Diabetes and Cardiovascular Disease
Crupi A.N., Haase J., Brandhorst S., Longo V.D.
Curr Diab Rep. 2020 Dec 10;20(12):83. doi: 10.1007/s11892-020-01362-4.
[33301104] - Prevention of unwanted recombination at damaged replication forks
Lehmann C.P., Jiménez-Martín A., Branzei D., Tercero J.A.
Curr Genet. 2020 Dec;66(6):1045-1051. doi: 10.1007/s00294-020-01095-7. Epub 2020 Jul 15.
[32671464] - Radiomics predicts response of individual HER2-amplified colorectal cancer liver metastases in patients treated with HER2-targeted therapy
Giannini V., Rosati S., Defeudis A., Balestra G., Vassallo L., Cappello G., Mazzetti S., De Mattia C., Rizzetto F., Torresin A., Sartore-Bianchi A., Siena S., Vanzulli A., Leone F., Zagonel V., Marsoni S., Regge D.
Int J Cancer. 2020 Dec 1;147(11):3215-3223. doi: 10.1002/ijc.33271. Epub 2020 Sep 14.
[32875550] - Detection of telomeric DNA:RNA hybrids using teloDRIP-qPCR
Rosso I., Di Fagagna F.D.
Int J Mol Sci. 2020 Dec 21;21(24):9774. doi: 10.3390/ijms21249774.
[33371452] - Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation
Osana S., Kitajima Y., Suzuki N., Nunomiya A., Takada H., Kubota T., Murayama K., Nagatomi R.
J Cell Physiol. 2020 Dec 30. doi: 10.1002/jcp.30237. Online ahead of print.
[33378552] - SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome
Sebestyén E., Marullo F., Lucini F., Petrini C., Bianchi A., Valsoni S., Olivieri I., Antonelli L., Gregoretti F., Oliva G., Ferrari F., Lanzuolo C.
Nat Commun. 2020 Dec 8;11(1):6274. doi: 10.1038/s41467-020-20048-9.
[33293552] - Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies
Claesson-Welsh L., Dejana E., McDonald D.M.
Trends Mol Med. 2020 Dec 10;S1471-4914(20)30293-8. doi: 10.1016/j.molmed.2020.11.006. Online ahead of print.
[33309601] - Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013–14) trial
Lugtenberg R.T., de Groot S., Kaptein A.A., Fischer M.J., Kranenbarg E.M.-K., Carpentier M.D.-D., Cohen D., de Graaf H., Heijns J.B., Portielje J.E.A., van de Wouw A.J., Imholz A.L.T., Kessels L.W., Vrijaldenhoven S., Baars A., Fiocco M., van der Hoeven J.J.M., Gelderblom H., Longo V.D., Pijl H., Kroep J.R., on behalf of the Dutch Breast Cancer Research Group (BOOG)
Breast Cancer Res Treat. 2021 Feb;185(3):741-758. doi: 10.1007/s10549-020-05991-x. Epub 2020 Nov 11.
[33179154] - Usp25 regulates egfr fate by modulating egf-induced ubiquitylation dynamics
Niño C.A., Wollscheid N., Giangreco G., Maspero E., Polo S.
Biomolecules. 2020 Nov 13;10(11):1548. doi: 10.3390/biom10111548.
[33202887] - Early changes of the standardized uptake values (SUVmax) predict the efficacy of everolimus-exemestane in patients with hormone receptor-positive metastatic breast cancer
Sirico M., Bernocchi O., Sobhani N., Giudici F., Corona S.P., Vernieri C., Nichetti F., Cappelletti M.R., Milani M., Strina C., Cervoni V., Barbieri G., Ziglioli N., Dester M., Bianchi G.V., Braud F.D., Generali D.
Cancers (Basel). 2020 Nov 10;12(11):3314. doi: 10.3390/cancers12113314.
[33182575] - Intra-tumour heterogeneity of diffuse large B-cell lymphoma involves the induction of diversified stroma-tumour interfaces
Sangaletti S., Iannelli F., Zanardi F., Cancila V., Portararo P., Botti L., Vacca D., Chiodoni C., Di Napoli A., Valenti C., Rizzello C., Vegliante M.C., Pisati F., Gulino A., Ponzoni M., Colombo M.P., Tripodo C.
EBioMedicine. 2020 Nov;61:103055. doi: 10.1016/j.ebiom.2020.103055. Epub 2020 Oct 20.
[33096480] - Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution
Orsenigo F., Conze L.L., Jauhiainen S., Corada M., Lazzaroni F., Malinverno M., Sundell V., Cunha S.I., Brännström J., Globisch M.A., Maderna C., Lampugnani M.G., Magnusson P.U., Dejana E.
Elife. 2020 Nov 3;9:e61413. doi: 10.7554/eLife.61413.
[33138917] - Impact of inter-reader contouring variability on textural radiomics of colorectal liver metastases
Rizzetto F., Calderoni F., De Mattia C., Defeudis A., Giannini V., Mazzetti S., Vassallo L., Ghezzi S., Sartore-Bianchi A., Marsoni S., Siena S., Regge D., Torresin A., Vanzulli A.
Eur Radiol Exp. 2020 Nov 10;4(1):62. doi: 10.1186/s41747-020-00189-8.
[33169295] - Genetics, Transcriptomics and Meta-Taxonomics in Visceral Leishmaniasis
Blackwell J.M., Fakiola M., Singh O.P.
Front Cell Infect Microbiol. 2020 Nov 25;10:590888. doi: 10.3389/fcimb.2020.590888. eCollection 2020.
[33324576] - X-Linked Alport Syndrome in Women: Genotype and Clinical Course in 24 Cases
Mastrangelo A., Giani M., Groppali E., Castorina P., Soldà G., Robusto M., Fallerini C., Bruttini M., Renieri A., Montini G.
Front Med (Lausanne). 2020 Nov 23;7:580376. doi: 10.3389/fmed.2020.580376. eCollection 2020.
[33330536] - Identification and characterization of cytotoxic amyloid-like regions in human Pbx-regulating protein-1
Doti N., Monti A., Bruckmann C., Calvanese L., Smaldone G., Caporale A., Falcigno L., D'Auria G., Blasi F., Ruvo M., Vitagliano L.
Int J Biol Macromol. 2020 Nov 15;163:618-629. doi: 10.1016/j.ijbiomac.2020.06.271. Epub 2020 Jul 4.
[32634512] - Fasting, dietary restriction, and immunosenescence
Longo V.D., Cortellino S.
J Allergy Clin Immunol. 2020 Nov;146(5):1002-1004. doi: 10.1016/j.jaci.2020.07.035. Epub 2020 Aug 24.
[32853639] - High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons
Cavallo F., Troglio F., Fagà G., Fancelli D., Shyti R., Trattaro S., Zanella M., D’Agostino G., Hughes J.M., Cera M.R., Pasi M., Gabriele M., Lazzarin M., Mihailovich M., Kooy F., Rosa A., Mercurio C., Varasi M., Testa G.
Mol Autism. 2020 Nov 19;11(1):88. doi: 10.1186/s13229-020-00387-6.
[33208191] - LifeTime and improving European healthcare through cell-based interceptive medicine
Rajewsky N., Almouzni G., Gorski S.A., Aerts S., Amit I., Bertero M.G., Bock C., Bredenoord A.L., Cavalli G., Chiocca S., Clevers H., De Strooper B., Eggert A., Ellenberg J., Fernández X.M., Figlerowicz M., Gasser S.M., Hubner N., Kjems J., Knoblich J.A., Krabbe G., Lichter P., Linnarsson S., Marine J.-C., Marioni J.C., Marti-Renom M.A., Netea M.G., Nickel D., Nollmann M., Novak H.R., Parkinson H., Piccolo S., Pinheiro I., Pombo A., Popp C., Reik W., Roman-Roman S., Rosenstiel P., Schultze J.L., Stegle O., Tanay A., Testa G., Thanos D., Theis F.J., Torres-Padilla M.-E., Valencia A., Vallot C., van Oudenaarden A., Vidal M., Voet T., Alberi L., Alexander S., Alexandrov T., Arenas E., Bagni C., Balderas R., Bandelli A., Becher B., Becker M., Beerenwinkel N., Benkirame M., Beyer M., Bickmore W., Biessen E.E.A.L., Blomberg N., Blumcke I., Bodenmiller B., Borroni B., Boumpas D.T., Bourgeron T., Bowers S., Braeken D., Brooksbank C., Brose N., Bruining H., Bury J., Caporale N., Cattoretti G., Chabane N., Chneiweiss H., Cook S.A., Curatolo P., de Jonge M.I., Deplancke B., De Strooper B., de Witte P., Dimmeler S., Draganski B., Drews A., Dumbrava C., Engelhardt S., Gasser T., Giamarellos-Bourboulis E.J., Graff C., Grün D., Gut I., Hansson O., Henshall D.C., Herland A., Heutink P., Heymans S.R.B., Heyn H., Huch M., Huitinga I., Jackowiak P., Jongsma K.R., Journot L., Junker J.P., Katz S., Kehren J., Kempa S., Kirchhof P., Klein C., Koralewska N., Korbel J.O., Kühnemund M., Lamond A.I., Lauwers E., Le Ber I., Leinonen V., Tobon A.L., Lundberg E., Lunkes A., Maatz H., Mann M., Marelli L., Matser V., Matthews P.M., Mechta-Grigoriou F., Menon R., Nielsen A.F., Pagani M., Pasterkamp R.J., Pitkänen A., Popescu V., Pottier C., Puisieux A., Rademakers R., Reiling D., Reiner O., Remondini D., Ritchie C., Rohrer J.D., Saliba A.-E., Sanchez-Valle R., Santosuosso A., Sauter A., Scheltema R.A., Scheltens P., Schiller H.B., Schneider A., Seibler P., Sheehan-Rooney K., Shields D., Sleegers K., Smit A.B., Smith K.G.C., Smolders I., Synofzik M., Tam W.L., Teichmann S., Thom M., Turco M.Y., van Beusekom H.M.M., Vandenberghe R., Van den Hoecke S., Van de Poel I., van der Ven A., van der Zee J., van Lunzen J., van Minnebruggen G., van Oudenaarden A., Van Paesschen W., van Swieten J., van Vught R., Verhage M., Verstreken P., Villa C.E., Vogel J., von Kalle C., Walter J., Weckhuysen S., Weichert W., Wood L., Ziegler A.-G., Zipp F., LifeTime Community Working Groups
Nature. 2020 Nov;587(7834):377-386. doi: 10.1038/s41586-020-2715-9. Epub 2020 Sep 7.
[32894860] - Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity
Waizenegger A., Urulangodi M., Lehmann C.P., Reyes T.A.C., Saugar I., Tercero J.A., Szakal B., Branzei D.
Nat Commun. 2020 Nov 12;11(1):5746. doi: 10.1038/s41467-020-19503-4.
[33184279] - Beyond lkb1 mutations in non-small cell lung cancer: Defining lkb1less phenotype to optimize patient selection and treatment
Borzi C., Galli G., Ganzinelli M., Signorelli D., Vernieri C., Garassino M.C., Sozzi G., Moro M.
Pharmaceuticals (Basel). 2020 Nov 13;13(11):385. doi: 10.3390/ph13110385.
[33202760] - Analysis of transcriptional modules during human fibroblast ageing
Lee Y., Shivashankar G.V.
Sci Rep. 2020 Nov 5;10(1):19086. doi: 10.1038/s41598-020-76117-y.
[33154459] - In vitro dexamethasone treatment does not induce alternative ATM transcripts in cells from Ataxia–Telangiectasia patients
Pozzi E., Giorgio E., Mancini C., Lo Buono N., Augeri S., Ferrero M., Di Gregorio E., Riberi E., Vinciguerra M., Nanetti L., Bianchi F.T., Sassi M.P., Costanzo V., Mariotti C., Funaro A., Cavalieri S., Brusco A.
Sci Rep. 2020 Nov 19;10(1):20182. doi: 10.1038/s41598-020-77352-z.
[33214630] - Polymorphisms within the RET proto-oncogene and risk of sporadic medullary thyroid carcinoma
Gemignani F., Romei C., Ciampi R., Corrado A., Melaiu O., Figlioli G., Bonotti A., Foddis R., Cristaudo A., Pellegrini G., Vivaldi A., Cipollini M., Landi S., Elisei R.
Thyroid. 2020 Nov;30(11):1579-1588. doi: 10.1089/thy.2019.0352. Epub 2020 May 5.
[32228166] - Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
Barnes D.R., Rookus M.A., McGuffog L., Leslie G., Mooij T.M., Dennis J., Mavaddat N., Adlard J., Ahmed M., Aittomäki K., Andrieu N., Andrulis I.L., Arnold N., Arun B.K., Azzollini J., Balmaña J., Barkardottir R.B., Barrowdale D., Benitez J., Berthet P., Białkowska K., Blanco A.M., Blok M.J., Bonanni B., Boonen S.E., Borg Å., Bozsik A., Bradbury A.R., Brennan P., Brewer C., Brunet J., Buys S.S., Caldés T., Caligo M.A., Campbell I., Christensen L.L., Chung W.K., Claes K.B.M., Colas C., Berthet P., Colas C., Collonge-Rame M.-A., Delnatte C., Faivre L., Giraud S., Lasset C., Mari V., Mebirouk N., Mouret-Fourme E., Schuster H., Stoppa-Lyonnet D., Adlard J., Ahmed M., Antoniou A., Barrowdale D., Brennan P., Brewer C., Cook J., Davidson R., Easton D., Eeles R., Evans D.G., Frost D., Hanson H., Izatt L., Ong K.-R., Side L., O’Shaughnessy-Kirwan A., Tischkowitz M., Walker L., Collonge-Rame M.-A., Cook J., Daly M.B., Davidson R., de la Hoya M., de Putter R., Delnatte C., Devilee P., Diez O., Ding Y.C., Domchek S.M., Dorfling C.M., Dumont M., Eeles R., Ejlertsen B., Engel C., Evans D.G., Faivre L., Foretova L., Fostira F., Friedlander M., Friedman E., Frost D., Ganz P.A., Garber J., Gehrig A., Gerdes A.-M., Gesta P., Giraud S., Glendon G., Godwin A.K., Goldgar D.E., González-Neira A., Greene M.H., Gschwantler-Kaulich D., Hahnen E., Hamann U., Hanson H., Hentschel J., Hogervorst F.B.L., Hooning M.J., Horvath J., Hu C., Hulick P.J., Imyanitov E.N., Chenevix-Trench G., Phillips K.-A., Spurdle A., Blok M., Devilee P., Hogervorst F., Hooning M., Koudijs M., Mensenkamp A., Meijers-Heijboer H., Rookus M., Engelen K., Andrieu N., Noguès C., Isaacs C., Izatt L., Izquierdo A., Jakubowska A., James P.A., Janavicius R., John E.M., Joseph V., Karlan B.Y., Kast K., Koudijs M., Kruse T.A., Kwong A., Laitman Y., Lasset C., Lazaro C., Lester J., Lesueur F., Liljegren A., Loud J.T., Lubiński J., Mai P.L., Manoukian S., Mari V., Mebirouk N., Meijers-Heijboer H.E.J., Meindl A., Mensenkamp A.R., Miller A., Montagna M., Mouret-Fourme E., Mukherjee S., Mulligan A.M., Nathanson K.L., Neuhausen S.L., Nevanlinna H., Niederacher D., Nielsen F.C., Nikitina-Zake L., Noguès C., Olah E., Olopade O.I., Ong K.-R., O’Shaughnessy-Kirwan A., Osorio A., Ott C.-E., Papi L., Park S.K., Parsons M.T., Pedersen I.S., Peissel B., Peixoto A., Peterlongo P., Pfeiler G., Phillips K.-A., Prajzendanc K., Pujana M.A., Radice P., Ramser J., Ramus S.J., Rantala J., Rennert G., Risch H.A., Robson M., Rønlund K., Salani R., Schuster H., Senter L., Shah P.D., Sharma P., Side L.E., Singer C.F., Slavin T.P., Soucy P., Southey M.C., Spurdle A.B., Steinemann D., Steinsnyder Z., Stoppa-Lyonnet D., Sutter C., Tan Y.Y., Teixeira M.R., Teo S.H., Thull D.L., Tischkowitz M., Tognazzo S., Toland A.E., Trainer A.H., Tung N., van Engelen K., van Rensburg E.J., Vega A., Vierstraete J., Wagner G., Walker L., Wang-Gohrke S., Wappenschmidt B., Weitzel J.N., Yadav S., Yang X., Yannoukakos D., Zimbalatti D., Offit K., Thomassen M., Couch F.J., Schmutzler R.K., Simard J., Easton D.F., Chenevix-Trench G., Antoniou A.C., GEMO Study Collaborators, EMBRACE Collaborators, !kConFab Investigators, HEBON Investigators, GENEPSO Investigators, on behalf of the Consortium of Investigators of Modifiers of BRCA and BRCA2
Genet Med. 2020 Oct;22(10):1653-1666. doi: 10.1038/s41436-020-0862-x. Epub 2020 Jul 15.
[32665703] - Membrane curvature, trans-membrane area asymmetry, budding, fission and organelle geometry
Mironov A.A., Mironov A., Derganc J., Beznoussenko G.V.
Int J Mol Sci. 2020 Oct 14;21(20):7594. doi: 10.3390/ijms21207594.
[33066582] - Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial
Maniaci G., La Cascia C., Giammanco A., Ferraro L., Chianetta R., Di Peri R., Sardella Z., Citarrella R., Mannella Y., Larcan S., Montana S., Mirisola M.G., Longo V., Rizzo M., La Barbera D.
J Clin Psychol. 2020 Oct;76(10):1807-1817. doi: 10.1002/jclp.22971. Epub 2020 May 11.
[32394438] - Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
Ghisleni A., Galli C., Monzo P., Ascione F., Fardin M.-A., Scita G., Li Q., Maiuri P., Gauthier N.C.
Nat Commun. 2020 Oct 9;11(1):5108. doi: 10.1038/s41467-020-18825-7.
[33037189] - Telomere damage induces internal loops that generate telomeric circles
Mazzucco G., Huda A., Galli M., Piccini D., Giannattasio M., Pessina F., Doksani Y.
Nat Commun. 2020 Oct 20;11(1):5297. doi: 10.1038/s41467-020-19139-4.
[33082350] - Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis
Bruckmann C., Tamburri S., De Lorenzi V., Doti N., Monti A., Mathiasen L., Cattaneo A., Ruvo M., Bachi A., Blasi F.
Sci Rep. 2020 Oct 8;10(1):16809. doi: 10.1038/s41598-020-74032-w.
[33033354] - DNA Damage Triggers a New Phase in Neurodegeneration
Pessina F., Gioia U., Brandi O., Farina S., Ceccon M., Francia S., d'Adda di Fagagna F.
Trends Genet. 2020 Oct 2;S0168-9525(20)30242-0. doi: 10.1016/j.tig.2020.09.006. Online ahead of print.
[33020022] - Telomere transcription in ageing
Aguado J., d'Adda di Fagagna F., Wolvetang E.
Ageing Res Rev. 2020 Sep;62:101115. doi: 10.1016/j.arr.2020.101115. Epub 2020 Jun 18.
[32565330] - Breaking Barriers in HER2+ Cancers
Siena S., Marsoni S., Sartore-Bianchi A.
Cancer Cell. 2020 Sep 14;38(3):317-319. doi: 10.1016/j.ccell.2020.07.012. Epub 2020 Aug 27.
[32857948] - miR-9-Mediated Inhibition of EFEMP1 Contributes to the Acquisition of Pro-Tumoral Properties in Normal Fibroblasts
Cosentino G., Romero-Cordoba S., Plantamura I., Cataldo A., Iorio M.V.
Cells. 2020 Sep 22;9(9):2143. doi: 10.3390/cells9092143.
[32972039] - JAM-A acts via C/EBP-α to promote claudin-5 expression and enhance endothelial barrier function
Kakogiannos N., Ferrari L., Giampietro C., Scalise A.A., Maderna C., Ravà M., Taddei A., Lampugnani M.G., Pisati F., Malinverno M., Martini E., Costa I., Lupia M., Cavallaro U., Beznoussenko G.V., Mironov A.A., Fernandes B., Rudini N., Dejana E., Giannotta M.
Circ Res. 2020 Sep 25;127(8):1056-1073. doi: 10.1161/CIRCRESAHA.120.316742. Epub 2020 Jul 15.
[32673519] - SARS-CoV2 vertical transmission with adverse effects on the newborn revealed through integrated immunohistochemical, electron microscopy and molecular analyses of Placenta
Facchetti F., Bugatti M., Drera E., Tripodo C., Sartori E., Cancila V., Papaccio M., Castellani R., Casola S., Boniotti M.B., Cavadini P., Lavazza A.
EBioMedicine. 2020 Sep;59:102951. doi: 10.1016/j.ebiom.2020.102951. Epub 2020 Aug 17.
[32818801] - Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication
Lerner L.K., Holzer S., Kilkenny M.L., Šviković S., Murat P., Schiavone D., Eldridge C.B., Bittleston A., Maman J.D., Branzei D., Stott K., Pellegrini L., Sale J.E.
EMBO J. 2020 Sep 15;39(18):e104185. doi: 10.15252/embj.2019104185. Epub 2020 Jul 23.
[32705708] - Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity
Matafora V., Farris F., Restuccia U., Tamburri S., Martano G., Bernardelli C., Sofia A., Pisati F., Casagrande F., Lazzari L., Marsoni S., Bonoldi E., Bachi A.
EMBO Rep. 2020 Sep 3;21(9):e50446. doi: 10.15252/embr.202050446. Epub 2020 Aug 4.
[32749065] - Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: The phase II HERACLES-B trial
Sartore-Bianchi A., Lonardi S., Martino C., Fenocchio E., Tosi F., Ghezzi S., Leone F., Bergamo F., Zagonel V., Ciardiello F., Ardizzoni A., Amatu A., Bencardino K., Valtorta E., Grassi E., Torri V., Bonoldi E., Sapino A., Vanzulli A., Regge D., Cappello G., Bardelli A., Trusolino L., Marsoni S., Siena S.
ESMO Open. 2020 Sep;5(5):e000911. doi: 10.1136/esmoopen-2020-000911.
[32988996] - A Spatially Resolved Dark- versus Light-Zone Microenvironment Signature Subdivides Germinal Center-Related Aggressive B Cell Lymphomas
Tripodo C., Zanardi F., Iannelli F., Mazzara S., Vegliante M., Morello G., Di Napoli A., Mangogna A., Facchetti F., Sangaletti S., Chiodoni C., VanShoiack? A., Jeyasekharan A.D., Casola S., Colombo M.P., Ponzoni M., Pileri S.A.
iScience. 2020 Sep 16;23(10):101562. doi: 10.1016/j.isci.2020.101562. eCollection 2020 Oct 23.
[33083730] - Cytosolic Crowding Drives the Dynamics of Both Genome and Cytosol in Escherichia coli Challenged with Sub-lethal Antibiotic Treatments
Wlodarski M., Mancini L., Raciti B., Sclavi B., Lagomarsino M.C., Cicuta P.
iScience. 2020 Sep 15;23(10):101560. doi: 10.1016/j.isci.2020.101560. eCollection 2020 Oct 23.
[33083729] - ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy
Sunderland P., Augustyniak J., Lenart J., Buźańska L., Carlessi L., Delia D., Sikora E.
Mech Ageing Dev. 2020 Sep;190:111296. doi: 10.1016/j.mad.2020.111296. Epub 2020 Jul 1.
[32621937] - ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration
Kidiyoor G.R., Li Q., Bastianello G., Bruhn C., Giovannetti I., Mohamood A., Beznoussenko G.V., Mironov A., Raab M., Piel M., Restuccia U., Matafora V., Bachi A., Barozzi S., Parazzoli D., Frittoli E., Palamidessi A., Panciera T., Piccolo S., Scita G., Maiuri P., Havas K.M., Zhou Z.-W., Kumar A., Bartek J., Wang Z.-Q., Foiani M.
Nat Commun. 2020 Sep 24;11(1):4828. doi: 10.1038/s41467-020-18580-9.
[32973141] - Taxonomic classification method for metagenomics based on core protein families with Core-Kaiju
Tovo A., Menzel P., Krogh A., Cosentino Lagomarsino M., Suweis S.
Nucleic Acids Res. 2020 Sep 18;48(16):e93. doi: 10.1093/nar/gkaa568.
[32633756] - Aromatase Inhibitors in Postmenopausal Women with Hormone Receptor-Positive Breast Cancer: Profiles of Psychological Symptoms and Quality of Life in Different Patient Clusters
Borreani C., Alfieri S., Infante G., Miceli R., Mariani P., Bosisio M., Vernieri C., Bianchi G.V., Capri G.
Oncology. 2021;99(2):84-95. doi: 10.1159/000509651. Epub 2020 Sep 29.
[32992318] - Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity
Chernorudskiy A., Varone E., Colombo S.F., Fumagalli S., Cagnotto A., Cattaneo A., Briens M., Baltzinger M., Kuhn L., Bachi A., Berardi A., Salmona M., Musco G., Borgese N., Lescure A., Zito E.
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21288-21298. doi: 10.1073/pnas.2003847117. Epub 2020 Aug 17.
[32817544] - Control of cytoskeletal dynamics by β-arrestin1/myosin vb signaling regulates endosomal sorting and scavenging activity of the atypical chemokine receptor ACKR2
Vacchini A., Cancellieri C., Milanesi S., Badanai S., Savino B., Bifari F., Locati M., Bonecchi R., Borroni E.M.
Vaccines (Basel). 2020 Sep 17;8(3):542. doi: 10.3390/vaccines8030542.
[32957704] - EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer
Amodio V., Yaeger R., Arcella P., Cancelliere C., Lamba S., Lorenzato A., Arena S., Montone M., Mussolin B., Bian Y., Whaley A., Pinnelli M., Murciano-Goroff Y.R., Vakiani E., Valeri N., Liao W.-L., Bhalkikar A., Thyparambil S., Zhao H.-Y., de Stanchina E., Marsoni S., Siena S., Bertotti A., Trusolino L., Li B.T., Rosen N., Di Nicolantonio F., Bardelli A., Misale S.
Cancer Discov. 2020 Aug;10(8):1129-1139. doi: 10.1158/2159-8290.CD-20-0187. Epub 2020 May 19.
[32430388] - Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle
Giovarelli M., Zecchini S., Martini E., Garrè M., Barozzi S., Ripolone M., Napoli L., Coazzoli M., Vantaggiato C., Roux-Biejat P., Cervia D., Moscheni C., Perrotta C., Parazzoli D., Clementi E., De Palma C.
Cell Death Differ. 2020 Aug;27(8):2383-2401. doi: 10.1038/s41418-020-0510-7. Epub 2020 Feb 10.
[32042098] - Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/β-catenin signaling
Cottarelli A., Corada M., Beznoussenko G.V., Mironov A.A., Globisch M.A., Biswas S., Huang H., Dimberg A., Magnusson P.U., Agalliu D., Lampugnani M.G., Dejana E.
Development. 2020 Aug 24;147(16):dev185140. doi: 10.1242/dev.185140.
[32747434] - Tuning mTORC1 activity dictates the response to LSD1 inhibition of acute myeloid leukemia
Abdel-Aziz A.K., Pallavicini I., Ceccacci E., Meroni G., Saadeldin M.K., Varasi M., Minucci S.
Haematologica. 2020 Aug;105(8):2105-2117. doi: 10.3324/haematol.2019.224501. Epub 2019 Sep 19.
[31537694] - Mutation rates in cancer susceptibility genes in patients with breast cancer with multiple primary cancers
Maxwell K.N., Wenz B.M., Kulkarni A., Wubbenhorst B., D’Andrea K., Weathers B., Goodman N., Vijai J., Lilyquist J., Hart S.N., Slavin T.P., Schrader K.A., Ravichandran V., Thomas T., Hu C., Robson M.E., Peterlongo P., Bonanni B., Ford J.M., Garber J.E., Neuhausen S.L., Shah P.D., Bradbury A.R., DeMichele A.M., Offit K., Weitzel J.N., Couch F.J., Domchek S.M., Nathanson K.L.
JCO Precis Oncol. 2020 Aug 19;4:PO.19.00301. doi: 10.1200/PO.19.00301. eCollection 2020.
[32954205] - The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing
Bruhn C., Ajazi A., Ferrari E., Lanz M.C., Batrin R., Choudhary R., Walvekar A., Laxman S., Longhese M.P., Fabre E., Smolka M.B., Foiani M.
Nat Commun. 2020 Aug 19;11(1):4154. doi: 10.1038/s41467-020-17961-4.
[32814778] - Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome
Capaci V., Bascetta L., Fantuz M., Beznoussenko G.V., Sommaggio R., Cancila V., Bisso A., Campaner E., Mironov A.A., Wiśniewski J.R., Ulloa Severino L., Scaini D., Bossi F., Lees J., Alon N., Brunga L., Malkin D., Piazza S., Collavin L., Rosato A., Bicciato S., Tripodo C., Mantovani F., Del Sal G.
Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5.
[32770028] - Fasting-mimicking diet plus chemotherapy in breast cancer treatment
Vernieri C., Ligorio F., Zattarin E., Rivoltini L., de Braud F.
Nat Commun. 2020 Aug 26;11(1):4274. doi: 10.1038/s41467-020-18194-1.
[32848145] - SMfinder: Small Molecules Finder for Metabolomics and Lipidomics Analysis
Martano G., Leone M., D'oro P., Matafora V., Cattaneo A., Masseroli M., Bachi A.
Anal Chem. 2020 Jul 7;92(13):8874-8882. doi: 10.1021/acs.analchem.0c00585. Epub 2020 Jun 16.
[32501676] - Ubiquitilated Fanconi ID complex embraces DNA
Achar Y.J., Foiani M.
Cell Res. 2020 Jul;30(7):554-555. doi: 10.1038/s41422-020-0345-2.
[32472046] - Transcriptome-wide association study of breast cancer risk by estrogen-receptor status
Feng H., Gusev A., Pasaniuc B., Wu L., Long J., Abu-full Z., Aittomäki K., Andrulis I.L., Anton-Culver H., Antoniou A.C., Arason A., Arndt V., Aronson K.J., Arun B.K., Asseryanis E., Auer P.L., Azzollini J., Balmaña J., Barkardottir R.B., Barnes D.R., Barrowdale D., Beckmann M.W., Behrens S., Benitez J., Bermisheva M., Białkowska K., Blanco A., Blomqvist C., Boeckx B., Bogdanova N.V., Bojesen S.E., Bolla M.K., Bonanni B., Borg A., Brauch H., Brenner H., Briceno I., Broeks A., Brüning T., Burwinkel B., Cai Q., Caldés T., Caligo M.A., Campbell I., Canisius S., Campa D., Carter B.D., Carter J., Castelao J.E., Chang-Claude J., Chanock S.J., Christiansen H., Chung W.K., Claes K.B.M., Clarke C.L., Couch F.J., Cox A., Cross S.S., Cybulski C., Czene K., Daly M.B., de la Hoya M., De Leeneer K., Dennis J., Devilee P., Diez O., Domchek S.M., Dörk T., dos-Santos-Silva I., Dunning A.M., Dwek M., Eccles D.M., Ejlertsen B., Ellberg C., Engel C., Eriksson M., Fasching P.A., Fletcher O., Flyger H., Fostira F., Friedman E., Fritschi L., Frost D., Gabrielson M., Ganz P.A., Gapstur S.M., Garber J., García-Closas M., García-Sáenz J.A., Gaudet M.M., Giles G.G., Glendon G., Godwin A.K., Goldberg M.S., Goldgar D.E., González-Neira A., Greene M.H., Gronwald J., Guénel P., Haiman C.A., Hall P., Hamann U., Hake C., He W., Heyworth J., Hogervorst F.B.L., Hollestelle A., Hooning M.J., Hoover R.N., Hopper J.L., Huang G., Hulick P.J., Humphreys K., Imyanitov E.N., Isaacs C., Jakimovska M., Jakubowska A., James P., Janavicius R., Jankowitz R.C., John E.M., Johnson N., Joseph V., Jung A., Karlan B.Y., Khusnutdinova E., Kiiski J.I., Konstantopoulou I., Kristensen V.N., Laitman Y., Lambrechts D., Lazaro C., Leroux D., Leslie G., Lester J., Lesueur F., Lindor N., Lindström S., Lo W.-Y., Loud J.T., Lubiński J., Makalic E., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Martens J.W.M., Martinez M.E., Matricardi L., Maurer T., Mavroudis D., McGuffog L., Meindl A., Menon U., Michailidou K., Kapoor P.M., Miller A., Montagna M., Moreno F., Moserle L., Mulligan A.M., Muranen T.A., Nathanson K.L., Neuhausen S.L., Nevanlinna H., Nevelsteen I., Nielsen F.C., Nikitina-Zake L., Offit K., Olah E., Olopade O.I., Olsson H., Osorio A., Papp J., Park-Simon T.-W., Parsons M.T., Pedersen I.S., Peixoto A., Peterlongo P., Peto J., Pharoah P.D.P., Phillips K.-A., Plaseska-Karanfilska D., Poppe B., Pradhan N., Prajzendanc K., Presneau N., Punie K., Pylkäs K., Radice P., Rantala J., Rashid M.U., Rennert G., Risch H.A., Robson M., Romero A., Saloustros E., Sandler D.P., Santos C., Sawyer E.J., Schmidt M.K., Schmidt D.F., Schmutzler R.K., Schoemaker M.J., Scott R.J., Sharma P., Shu X.-O., Simard J., Singer C.F., Skytte A.-B., Soucy P., Southey M.C., Spinelli J.J., Spurdle A.B., Stone J., Swerdlow A.J., Tapper W.J., Taylor J.A., Teixeira M.R., Terry M.B., Teulé A., Thomassen M., Thöne K., Thull D.L., Tischkowitz M., Toland A.E., Tollenaar R.A.E.M., Torres D., Truong T., Tung N., Vachon C.M., van Asperen C.J., van den Ouweland A.M.W., van Rensburg E.J., Vega A., Viel A., Vieiro-Balo P., Wang Q., Wappenschmidt B., Weinberg C.R., Weitzel J.N., Wendt C., Winqvist R., Yang X.R., Yannoukakos D., Ziogas A., Milne R.L., Easton D.F., Chenevix-Trench G., Zheng W., Kraft P., Jiang X., GEMO Study Collaborators, EMBRACE Collaborators, GC-HBOC study Collaborators, ABCTB Investigators, HEBON Investigators, BCFR Investigators, OCGN Investigators
Genet Epidemiol. 2020 Jul;44(5):442-468. doi: 10.1002/gepi.22288. Epub 2020 Mar 1.
[32115800] - A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer
Di Tano M., Longo V.D.
Mol Cell Oncol. 2020 Jul 29;7(5):1791671. doi: 10.1080/23723556.2020.1791671. eCollection 2020.
[32944646] - Author Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression (Nature, (2020), 583, 7817, (620-624), 10.1038/s41586-020-2502-7)
Caffa I., Spagnolo V., Vernieri C., Valdemarin F., Becherini P., Wei M., Brandhorst S., Zucal C., Driehuis E., Ferrando L., Piacente F., Tagliafico A., Cilli M., Mastracci L., Vellone V.G., Piazza S., Cremonini A.L., Gradaschi R., Mantero C., Passalacqua M., Ballestrero A., Zoppoli G., Cea M., Arrighi A., Odetti P., Monacelli F., Salvadori G., Cortellino S., Clevers H., De Braud F., Sukkar S.G., Provenzani A., Longo V.D., Nencioni A.
Nature. 2020 Jul;583(7817):620-624. doi: 10.1038/s41586-020-2502-7. Epub 2020 Jul 15.
[32669709] - Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties
Tito Panciera, Anna Citron, Daniele Di Biagio, Giusy Battilana, Alessandro Gandin, Stefano Giulitti, Mattia Forcato, Silvio Bicciato, Valeria Panzetta, Sabato Fusco, Luca Azzolin, Antonio Totaro, Angelo Paolo Dei Tos, Matteo Fassan, Vincenzo Vindigni, Franco Bassetto, Antonio Rosato, Giovanna Brusatin, Michelangelo Cordenonsi, Stefano Piccolo
Nat Mater. 2020 Jul;19(7):797-806. doi: 10.1038/s41563-020-0615-x. Epub 2020 Feb 17.
[32665580] - IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules
Panciera T., Citron A., Di Biagio D., Battilana G., Gandin A., Giulitti S., Forcato M., Bicciato S., Panzetta V., Fusco S., Azzolin L., Totaro A., Dei Tos A.P., Fassan M., Vindigni V., Bassetto F., Rosato A., Brusatin G., Cordenonsi M., Piccolo S.
Nat Mater. 2020 Jul;19(7):797-806. doi: 10.1038/s41563-020-0615-x. Epub 2020 Feb 17.
[32066931] - Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal
Tamborero D., Dienstmann R., Rachid M.H., Boekel J., Baird R., Braña I., De Petris L., Yachnin J., Massard C., Opdam F.L., Schlenk R., Vernieri C., Garralda E., Masucci M., Villalobos X., Chavarria E., Anand S., Azaro A., Baars D., Bajalica-Lagercrantz S., Balmaña J., Bergh J., Bierkens M., Blomqvist L., Doherty G.J., Forest A., Fornerone V., Funingana I.G., Gabaldi P., Hartman J., Horak P., Karlsson C., Kasanicki M., Kreutzfeldt S., Lewensohn R., Lindberg J., Lopez C., Lundqvist A., Martin-Romano P., Martin J.-E., Meijer G., Muñoz S., Camus M.N., Nicotra C., Nuciforo P., Oberrauch P., Östling P., Piris-Giménez A., Provenzano E., Rouleau E., Rowell J., Saavedra O., Valdivia I.S., Scoazec G., Seamon K., Tischkowitz M., van der Kolk L., van der Noll R., Vis D., Vivancos A., von Gertten C., Wennborg A., Wessels L., Wirta V., Wolfart J., Calvo F., Fröhling S., Eggermont A., Apolone G., Voest E.E., Caldas C., Tabernero J., Ernberg I., Rodon J., Lehtiö J., Cancer Core Europe consortium
Nat Med. 2020 Jul;26(7):992-994. doi: 10.1038/s41591-020-0969-2.
[32632195] - OligoMinerApp: a web-server application for the design of genome-scale oligonucleotide in situ hybridization probes through the flexible OligoMiner environment
Passaro M., Martinovic M., Bevilacqua V., Hershberg E.A., Rossetti G., Beliveau B.J., Bonnal R.J.P., Pagani M.
Nucleic Acids Res. 2020 Jul 2;48(W1):W332-W339. doi: 10.1093/nar/gkaa251.
[32313927] - The potential role of metformin in the treatment of patients with pancreatic neuroendocrine tumors: a review of preclinical to clinical evidence
Pusceddu S., Vernieri C., Prinzi N., Torchio M., Coppa J., Antista M., Niger M., Milione M., Giacomelli L., Corti F., Prisciandaro M., Monteleone M., Colombo E., Di Bartolomeo M., de Braud F.
Therap Adv Gastroenterol. 2020 Jul 31;13:1756284820927271. doi: 10.1177/1756284820927271. eCollection 2020.
[32821286] - The Role of Tricellulin in Epithelial Jamming and Unjamming via Segmentation of Tricellular Junctions
Lohmann S., Giampietro C., Pramotton F.M., Al-Nuaimi D., Poli A., Maiuri P., Poulikakos D., Ferrari A.
Adv Sci (Weinh). 2020 Jun 8;7(15):2001213. doi: 10.1002/advs.202001213. eCollection 2020 Aug.
[32775171] - Correction to: Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimicking diet in patients with type 2 diabetes (BMC Endocrine Disorders, (2020), 20, 1, (94), 10.1186/s12902-020-00576-7)
van den Burg E.L., Schoonakker M.P., van Peet P.G., van den Akker-van Marle M.E., van Dijk K.W., Longo V.D., Lamb H.J., Numans M.E., Pijl H.
BMC Endocr Disord. 2020 Jun 24;20(1):94. doi: 10.1186/s12902-020-00576-7.
[32580710] - Haspin regulates Ras localization to promote Cdc24-driven mitotic depolarization
Quadri R., Galli M., Galati E., Rotondo G., Gallo G.R., Panigada D., Plevani P., Muzi-Falconi M.
Cell Discov. 2020 Jun 23;6:42. doi: 10.1038/s41421-020-0170-2. eCollection 2020.
[32595981] - Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson’s Disease and Atypical Parkinsonisms
Mazzetti S., De Leonardis M., Gagliardi G., Calogero A.M., Basellini M.J., Madaschi L., Costa I., Cacciatore F., Spinello S., Bramerio M., Cilia R., Rolando C., Giaccone G., Pezzoli G., Cappelletti G.
Front Neurosci. 2020 Jun 23;14:624. doi: 10.3389/fnins.2020.00624. eCollection 2020.
[32655357] - Obesity is a risk factor for acute promyelocytic leukemia: Evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty acid metabolism
Mazzarella L., Botteri E., Matthews A., Gatti E., Di Salvatore D., Bagnardi V., Breccia M., Montesinos P., Bernal T., Gil C., Ley T.J., Sanz M., Bhaskaran K., Coco F.L., Pelicci P.G.
Haematologica. 2020 Jun;105(6):1559-1566. doi: 10.3324/haematol.2019.223925. Epub 2019 Sep 12.
[31515354] - Structure of the enterocyte transcytosis compartments during lipid absorption
Sesorova I.S., Karelina N.R., Kazakova T.E., Parashuraman S., Zdorikova M.A., Dimov I.D., Seliverstova E.V., Beznoussenko G.V., Mironov A.A.
Histochem Cell Biol. 2020 Jun;153(6):413-429. doi: 10.1007/s00418-020-01851-3. Epub 2020 Mar 11.
[32162136] - Central Nervous System as Possible Site of Relapse in ERBB2 -Positive Metastatic Colorectal Cancer: Long-term Results of Treatment with Trastuzumab and Lapatinib
Sartore-Bianchi A., Lonardi S., Aglietta M., Martino C., Ciardiello F., Marsoni S., Siena S.
JAMA Oncol. 2020 Jun 1;6(6):927-929. doi: 10.1001/jamaoncol.2020.0571.
[32324210] - Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
de Groot S., Lugtenberg R.T., Cohen D., Welters M.J.P., Ehsan I., Vreeswijk M.P.G., Smit V.T.H.B.M., de Graaf H., Heijns J.B., Portielje J.E.A., van de Wouw A.J., Imholz A.L.T., Kessels L.W., Vrijaldenhoven S., Baars A., Kranenbarg E.M.-K., Carpentier M.D.-D., Putter H., van der Hoeven J.J.M., Nortier J.W.R., Longo V.D., Pijl H., Kroep J.R., de Graaf H., Heijns J.B., Portielje J.E.A., van de Wouw A.J., Imholz A.L.T., Kessels L.W., Vrijaldenhoven S., Baars A., Göker E., Pas A.J.M., Honkoop A.H., van Leeuwen-Stok A.E., Kroep J.R., Dutch Breast Cancer Research Group (BOOG)
Nat Commun. 2020 Jun 23;11(1):3083. doi: 10.1038/s41467-020-16138-3.
[32576828] - A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior
Schiano Lomoriello I., Giangreco G., Iavarone C., Tordonato C., Caldieri G., Serio G., Confalonieri S., Freddi S., Bianchi F., Pirroni S., Bertalot G., Viale G., Disalvatore D., Tosoni D., Malabarba M.G., Disanza A., Scita G., Pece S., Pilcher B.K., Vecchi M., Sigismund S., Di Fiore P.P.
Nat Commun. 2020 Jun 15;11(1):3020. doi: 10.1038/s41467-020-16836-y.
[32541686] - Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Zhang H., Ahearn T.U., Lecarpentier J., Barnes D., Beesley J., Qi G., Jiang X., O’Mara T.A., Zhao N., Bolla M.K., Dunning A.M., Dennis J., Wang Q., Ful Z.A., Aittomäki K., Andrulis I.L., Anton-Culver H., Arndt V., Aronson K.J., Arun B.K., Auer P.L., Azzollini J., Barrowdale D., Becher H., Beckmann M.W., Behrens S., Benitez J., Bermisheva M., Bialkowska K., Blanco A., Blomqvist C., Bogdanova N.V., Bojesen S.E., Bonanni B., Bondavalli D., Borg A., Brauch H., Brenner H., Briceno I., Broeks A., Brucker S.Y., Brüning T., Burwinkel B., Buys S.S., Byers H., Caldés T., Caligo M.A., Calvello M., Campa D., Castelao J.E., Chang-Claude J., Chanock S.J., Christiaens M., Christiansen H., Chung W.K., Claes K.B.M., Clarke C.L., Cornelissen S., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Devilee P., Diez O., Domchek S.M., Dörk T., Dwek M., Eccles D.M., Ekici A.B., Evans D.G., Fasching P.A., Figueroa J., Foretova L., Fostira F., Friedman E., Frost D., Gago-Dominguez M., Gapstur S.M., Garber J., García-Sáenz J.A., Gaudet M.M., Gayther S.A., Giles G.G., Godwin A.K., Goldberg M.S., Goldgar D.E., González-Neira A., Greene M.H., Gronwald J., Guénel P., Häberle L., Hahnen E., Haiman C.A., Hake C.R., Hall P., Hamann U., Harkness E.F., Heemskerk-Gerritsen B.A.M., Hillemanns P., Hogervorst F.B.L., Holleczek B., Hollestelle A., Hooning M.J., Hoover R.N., Hopper J.L., Howell A., Huebner H., Hulick P.J., Imyanitov E.N., Isaacs C., Izatt L., Jager A., Jakimovska M., Jakubowska A., James P., Janavicius R., Janni W., John E.M., Jones M.E., Jung A., Kaaks R., Kapoor P.M., Karlan B.Y., Keeman R., Khan S., Khusnutdinova E., Kitahara C.M., Ko Y.-D., Konstantopoulou I., Koppert L.B., Koutros S., Kristensen V.N., Laenkholm A.-V., Lambrechts D., Larsson S.C., Laurent-Puig P., Lazaro C., Lazarova E., Lejbkowicz F., Leslie G., Lesueur F., Lindblom A., Lissowska J., Lo W.-Y., Loud J.T., Lubinski J., Lukomska A., MacInnis? R.J., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Martinez M.E., Matricardi L., McGuffog L., McLean C., Mebirouk N., Meindl A., Menon U., Miller A., Mingazheva E., Montagna M., Mulligan A.M., Mulot C., Muranen T.A., Nathanson K.L., Neuhausen S.L., Nevanlinna H., Neven P., Newman W.G., Nielsen F.C., Nikitina-Zake L., Nodora J., Offit K., Olah E., Olopade O.I., Olsson H., Orr N., Papi L., Papp J., Park-Simon T.-W., Parsons M.T., Peissel B., Peixoto A., Peshkin B., Peterlongo P., Peto J., Phillips K.-A., Piedmonte M., Plaseska-Karanfilska D., Prajzendanc K., Prentice R., Prokofyeva D., Rack B., Radice P., Ramus S.J., Rantala J., Rashid M.U., Rennert G., Rennert H.S., Risch H.A., Romero A., Rookus M.A., Rübner M., Rüdiger T., Saloustros E., Sampson S., Sandler D.P., Sawyer E.J., Scheuner M.T., Schmutzler R.K., Schneeweiss A., Schoemaker M.J., Schöttker B., Schürmann P., Senter L., Sharma P., Sherman M.E., Shu X.-O., Singer C.F., Smichkoska S., Soucy P., Southey M.C., Spinelli J.J., Stone J., Stoppa-Lyonnet D., Swerdlow A.J., Szabo C.I., Tamimi R.M., Tapper W.J., Taylor J.A., Teixeira M.R., Terry M.B., Thomassen M., Thull D.L., Tischkowitz M., Toland A.E., Tollenaar R.A.E.M., Tomlinson I., Torres D., Troester M.A., Truong T., Tung N., Untch M., Vachon C.M., van den Ouweland A.M.W., van der Kolk L.E., van Veen E.M., vanRensburg E.J., Vega A., Wappenschmidt B., Weinberg C.R., Weitzel J.N., Wildiers H., Winqvist R., Wolk A., Yang X.R., Yannoukakos D., Zheng W., Zorn K.K., Milne R.L., Kraft P., Simard J., Pharoah P.D.P., Michailidou K., Antoniou A.C., Schmidt M.K., Chenevix-Trench G., Easton D.F., Chatterjee N., García-Closas M., !kConFab Investigators, ABCTB Investigators, EMBRACE Study, GEMO Study Collaborators
Nat Genet. 2020 Jun;52(6):572-581. doi: 10.1038/s41588-020-0609-2. Epub 2020 May 18.
[32424353] - GSK-3 is an RNA polymerase II phospho-CTD kinase
Nieto Moreno N., Villafañez F., Giono L.E., Cuenca C., Soria G., Muñoz M.J., Kornblihtt A.R.
Nucleic Acids Res. 2020 Jun 19;48(11):6068-6080. doi: 10.1093/nar/gkaa322.
[32374842] - Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Liu J., Prager-van der Smissen W.J.C., Collée J.M., Bolla M.K., Wang Q., Michailidou K., Dennis J., Ahearn T.U., Aittomäki K., Ambrosone C.B., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arndt V., Arnold N., Aronson K.J., Augustinsson A., Auvinen P., Becher H., Beckmann M.W., Behrens S., Bermisheva M., Bernstein L., Bogdanova N.V., Bogdanova-Markov N., Bojesen S.E., Brauch H., Brenner H., Briceno I., Brucker S.Y., Brüning T., Burwinkel B., Cai Q., Cai H., Campa D., Canzian F., Castelao J.E., Chang-Claude J., Chanock S.J., Choi J.-Y., Christiaens M., Clarke C.L., Couch F.J., Czene K., Daly M.B., Devilee P., Dos-Santos-Silva I., Dwek M., Eccles D.M., Eliassen A.H., Fasching P.A., Figueroa J., Flyger H., Fritschi L., Gago-Dominguez M., Gapstur S.M., García-Closas M., García-Sáenz J.A., Gaudet M.M., Giles G.G., Goldberg M.S., Goldgar D.E., Guénel P., Haiman C.A., Håkansson N., Hall P., Harrington P.A., Hart S.N., Hartman M., Hillemanns P., Hopper J.L., Hou M.-F., Hunter D.J., Huo D., Ito H., Iwasaki M., Jakimovska M., Jakubowska A., John E.M., Kaaks R., Kang D., Keeman R., Khusnutdinova E., Kim S.-W., Kraft P., Kristensen V.N., Kurian A.W., Le Marchand L., Li J., Lindblom A., Lophatananon A., Luben R.N., Lubiński J., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Mariapun S., Matsuo K., Maurer T., Mavroudis D., Meindl A., Menon U., Milne R.L., Muir K., Mulligan A.M., Neuhausen S.L., Nevanlinna H., Offit K., Olopade O.I., Olson J.E., Olsson H., Orr N., Park S.K., Peterlongo P., Peto J., Plaseska-Karanfilska D., Presneau N., Rack B., Rau-Murthy R., Rennert G., Rennert H.S., Rhenius V., Romero A., Ruebner M., Saloustros E., Schmutzler R.K., Schneeweiss A., Scott C., Shah M., Shen C.-Y., Shu X.-O., Simard J., Sohn C., Southey M.C., Spinelli J.J., Tamimi R.M., Tapper W.J., Teo S.H., Terry M.B., Torres D., Truong T., Untch M., Vachon C.M., van Asperen C.J., Wolk A., Yamaji T., Zheng W., Ziogas A., Ziv E., Torres-Mejía G., Dörk T., Swerdlow A.J., Hamann U., Schmidt M.K., Dunning A.M., Pharoah P.D.P., Easton D.F., Hooning M.J., Martens J.W.M., Hollestelle A., NBCS Collaborators, ABCTB Investigators
Sci Rep. 2020 Jun 16;10(1):9688. doi: 10.1038/s41598-020-65665-y.
[32546843] - Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
Di Tano M., Raucci F., Vernieri C., Caffa I., Buono R., Fanti M., Brandhorst S., Curigliano G., Nencioni A., de Braud F., Longo V.D.
Nat Commun. 2020 May 11;11(1):2332. doi: 10.1038/s41467-020-16243-3.
[32393788] - Exploring the controversial role of PI3K signalling in CD4+ regulatory T (T-Reg) cells
Poli A., Fiume R., Mongiorgi S., Zaurito A., Sheth B., Vidalle M.C., Hamid S.A., Kimber S., Campagnoli F., Ratti S., Rusciano I., Faenza I., Manzoli L., Divecha N.
Adv Biol Regul. 2020 May;76:100722. doi: 10.1016/j.jbior.2020.100722. Epub 2020 Apr 23.
[32362560] - Metabolism and immune modulation in patients with solid tumors: Systematic review of preclinical and clinical evidence
Mirabile A., Rivoltini L., Daveri E., Vernieri C., Mele R., Porcu L., Lazzari C., Bulotta A., Viganò M.G., Cascinu S., Gregorc V.
Cancers (Basel). 2020 May 4;12(5):1153. doi: 10.3390/cancers12051153.
[32375310] - Senataxin Ortholog Sen1 Limits DNA:RNA Hybrid Accumulation at DNA Double-Strand Breaks to Control End Resection and Repair Fidelity
Rawal C.C., Zardoni L., Di Terlizzi M., Galati E., Brambati A., Lazzaro F., Liberi G., Pellicioli A.
Cell Rep. 2020 May 5;31(5):107603. doi: 10.1016/j.celrep.2020.107603.
[32375052] - DHA Affects Microtubule Dynamics Through Reduction of Phospho-TCTP Levels and Enhances the Antiproliferative Effect of T-DM1 in Trastuzumab-Resistant HER2-Positive Breast Cancer Cell Lines
D'Amico S., Krasnowska E.K., Manni I., Toietta G., Baldari S., Piaggio G., Ranalli M., Gambacurta A., Vernieri C., Di Giacinto F., Bernassola F., de Braud F., Lucibello M.
Cells. 2020 May 19;9(5):1260. doi: 10.3390/cells9051260.
[32438775] - SAMHD1 acts at stalled replication forks to prevent interferon induction [SAMHD1 agit sur les fourches de réplication bloquées pour empêcher l’induction d’interféron]
Coquel F., Silva M.J., Técher H., Zadorozhny K., Sharma S., Nieminuszczy J., Mettling C., Dardillac E., Barthe A., Schmitz A.L., Promonet A., Cribier A., Sarrazin A., Niedzwiedz W., Lopez B., Costanzo V., Krejci L., Chabes A., Benkirane M., Lin Y.L., Pasero P.
Nature. 2018 May;557(7703):57-61. doi: 10.1038/s41586-018-0050-1. Epub 2018 Apr 18.
[29670289] - LKB1 mutations are not associated with the efficacy of first-line and second-line chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC): a post hoc analysis of the TAILOR trial
Vernieri C., Ganzinelli M., Rulli E., Farina G., Bettini A.C., Bareggi C., Rosso L., Signorelli D., Galli G., Lo Russo G., Proto C., Moro M., Indraccolo S., Busico A., Sozzi G., Torri V., Marabese M., Massimo B., Garassino M.C.
ESMO Open. 2020 May;5(3):e000748. doi: 10.1136/esmoopen-2020-000748.
[32467099] - Dysfunctional polycomb transcriptional repression contributes to lamin A/C-dependent muscular dystrophy
Bianchi A., Mozzetta C., Pegoli G., Lucini F., Valsoni S., Rosti V., Petrini C., Cortesi A., Gregoretti F., Antonelli L., Oliva G., de Bardi M., Rizzi R., Bodega B., Pasini D., Ferrari F., Bearzi C., Lanzuolo C.
J Clin Invest. 2020 May 1;130(5):2408-2421. doi: 10.1172/JCI128161.
[31999646] - Modelling cancer cell budding in-vitro as a self-organised, non-equilibrium growth process
Agosti A., Marchesi S., Scita G., Ciarletta P.
J Theor Biol. 2020 May 7;492:110203. doi: 10.1016/j.jtbi.2020.110203. Epub 2020 Feb 15.
[32067938] - Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
Nastały P., Purushothaman D., Marchesi S., Poli A., Lendenmann T., Kidiyoor G.R., Beznoussenko G.V., Lavore S., Romano O.M., Poulikakos D., Lagomarsino M.C., Mironov A.A., Ferrari A., Maiuri P.
Nat Commun. 2020 May 1;11(1):2122. doi: 10.1038/s41467-020-15910-9.
[32358486] - Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3
Boulpicante M., Darrigrand R., Pierson A., Salgues V., Rouillon M., Gaudineau B., Khaled M., Cattaneo A., Bachi A., Cascio P., Apcher S.
Oncoimmunology. 2020 May 21;9(1):1761205. doi: 10.1080/2162402X.2020.1761205.
[32923122] - Berberine in the treatment of metabolism-related chronic diseases: A drug cloud (dCloud) effect to target multifactorial disorders
Kong W.-J., Vernieri C., Foiani M., Jiang J.-D.
Pharmacol Ther. 2020 May;209:107496. doi: 10.1016/j.pharmthera.2020.107496. Epub 2020 Jan 27.
[32001311] - Fibroblast rejuvenation by mechanical reprogramming and redifferentiation
Roy B., Yuan L., Lee Y., Bharti A., Mitra A., Shivashankar G.V.
Proc Natl Acad Sci U S A. 2020 May 12;117(19):10131-10141. doi: 10.1073/pnas.1911497117. Epub 2020 Apr 29.
[32350144] - Propranolol for familial cerebral cavernous malformation (Treat_CCM): Study protocol for a randomized controlled pilot trial
Lanfranconi S., Scola E., Bertani G.A., Zarino B., Pallini R., D'Alessandris G., Mazzon E., Marino S., Carriero M.R., Scelzo E., Faragò G., Castori M., Fusco C., Petracca A., D'Agruma L., Tassi L., D'Orio P., Lampugnani M.G., Nicolis E.B., Vasamì A., Novelli D., Torri V., Meessen J.M.T.A., Salman R.A.-S., Dejana E., Latini R., Pignotti F., Sturiale C., Albanese A., Zarino B., Valcamonica G., Ronchi D., Pogliani S., De Grazia U., Bossi C., Ciurleo R., Raggi P., Simeone A., Balconi G., Foresta A., Buratti M.G., Carrara M., Fernandez M.L.O., Treglia R., Maggioni A.P., Beghi E., Tettamanti M., Regna-Gladin C., Prelle A., Mangiavacchi M., Poloni M., Lazzaroni F., Malinverno M., Ungaro C., Raucci F.
Trials. 2020 May 12;21(1):401. doi: 10.1186/s13063-020-4202-x.
[32398113] - Everolimus versus alpelisib in advanced hormone receptor-positive HER2-negative breast cancer: Targeting different nodes of the PI3K/AKT/mTORC1 pathway with different clinical implications
Vernieri C., Corti F., Nichetti F., Ligorio F., Manglaviti S., Zattarin E., Rea C.G., Capri G., Bianchi G.V., De Braud F.
Breast Cancer Res. 2020 Apr 6;22(1):33. doi: 10.1186/s13058-020-01271-0.
[32252811] - Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation
Fioravanti R., Romanelli A., Mautone N., Di Bello E., Rovere A., Corinti D., Zwergel C., Valente S., Rotili D., Botrugno O.A., Dessanti P., Vultaggio S., Vianello P., Cappa A., Binda C., Mattevi A., Minucci S., Mercurio C., Varasi M., Mai A.
ChemMedChem. 2020 Apr 3;15(7):643-658. doi: 10.1002/cmdc.201900730. Epub 2020 Feb 14.
[32003940] - Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Smith R.O., Ninchoji T., Gordon E., André H., Dejana E., Vestweber D., Kvanta A., Claesson-Welsh L.
Elife. 2020 Apr 21;9:e54056. doi: 10.7554/eLife.54056.
[32312382] - Multivariate analysis reveals activation-primed fibroblast geometric states in engineered 3D tumor microenvironments
Venkatachalapathy S., Jokhun D.S., Shivashankar G.V.
Mol Biol Cell. 2020 Apr 1;31(8):803-812. doi: 10.1091/mbc.E19-08-0420. Epub 2020 Feb 5.
[32023167] - The dark side of RNA:DNA hybrids
Brambati A., Zardoni L., Nardini E., Pellicioli A., Liberi G.
Mutat Res. Apr-Jun 2020;784:108300. doi: 10.1016/j.mrrev.2020.108300. Epub 2020 Feb 29.
[32430097] - Heterogeneity Fair: Commentary to Menter and Tzankov "lymphomas and Their Microenvironment: A Multifaceted Relationship
Tripodo C.
Pathobiology. 2020;87(2):155-158. doi: 10.1159/000507374. Epub 2020 Apr 9.
[32272477] - Single rod-shaped cell fluctuations from stochastic surface and volume growth rates
Romano O.M., Cosentino Lagomarsino M.
Phys Rev E. 2020 Apr;101(4-1):042403. doi: 10.1103/PhysRevE.101.042403.
[32422852] - Sodium butyrate induces genotoxic stress in function of photoperiod variations and differentially modulates the expression of genes involved in chromatin modification and DNA repair in Petunia hybrida seedlings
Pagano A., L’Andolina C., Sabatini M.E., de Sousa Araújo S., Balestrazzi A., Macovei A.
Planta. 2020 Apr 29;251(5):102. doi: 10.1007/s00425-020-03392-4.
[32350684] - Predicting cell lineages using autoencoders and optimal transport
Yang K.D., Damodaran K., Venkatachalapathy S., Soylemezoglu A.C., Shivashankar G.V., Uhler C.
PLoS Comput Biol. 2020 Apr 28;16(4):e1007828. doi: 10.1371/journal.pcbi.1007828. eCollection 2020 Apr.
[32343706] - Myosin filament-based regulation of the dynamics of contraction in heart muscle
Brunello E., Fusi L., Ghisleni A., Park-Holohan S.-J., Ovejero J.G., Narayanan T., Irving M.
Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8177-8186. doi: 10.1073/pnas.1920632117. Epub 2020 Mar 27.
[32220962] - The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks
Jiménez-Martín A., Saugar I., Joseph C.R., Mayer A., Lehmann C.P., Szakal B., Branzei D., Tercero J.A.
Sci Adv. 2020 Apr 8;6(15):eaaz3327. doi: 10.1126/sciadv.aaz3327. eCollection 2020 Apr.
[32285001] - Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation
Ravasio R., Ceccacci E., Nicosia L., Hosseini A., Rossi P.L., Barozzi I., Fornasari L., Zuffo R.D., Valente S., Fioravanti R., Mercurio C., Varasi M., Mattevi A., Mai A., Pavesi G., Bonaldi T., Minucci S.
Sci Adv. 2020 Apr 8;6(15):eaax2746. doi: 10.1126/sciadv.aax2746. eCollection 2020 Apr.
[32284990] - Identification of PLK1 as a new therapeutic target in mucinous ovarian carcinoma
Affatato R., Carrassa L., Chilà R., Lupi M., Restelli V., Damia G.
Cancers (Basel). 2020 Mar 13;12(3):672. doi: 10.3390/cancers12030672.
[32183025] - Vitamin c restricts the emergence of acquired resistance to EGFR-targeted therapies in colorectal cancer
Lorenzato A., Magrì A., Matafora V., Audrito V., Arcella P., Lazzari L., Montone M., Lamba S., Deaglio S., Siena S., Bertotti A., Trusolino L., Bachi A., Di Nicolantonio F., Bardelli A., Arena S.
Cancers (Basel). 2020 Mar 14;12(3):685. doi: 10.3390/cancers12030685.
[32183295] - Oral capecitabine-vinorelbine is associated with longer overall survival when compared to single-agent capecitabine in patients with hormone receptor-positive advanced breast cancer
Vernieri C., Prisciandaro M., Nichetti F., Lobefaro R., Peverelli G., Ligorio F., Zattarin E., Cona M.S., Sepe P., Corti F., Manglaviti S., Brambilla M., Re B., Belfiore A., Pruneri G., Celio L., Mariani G., Bianchi G.V., Rivoltini L., Capri G., de Braud F.
Cancers (Basel). 2020 Mar 6;12(3):617. doi: 10.3390/cancers12030617.
[32155941] - A subset of colorectal cancers with cross-sensitivity to olaparib and oxaliplatin
Arena S., Corti G., Durinikova E., Montone M., Reilly N.M., Russo M., Lorenzato A., Arcella P., Lazzari L., Rospo G., Pagani M., Cancelliere C., Negrino C., Isella C., Bartolini A., Cassingena A., Amatu A., Mauri G., Sartore-Bianchi A., Mittica G., Medico E., Marsoni S., Linnebacher M., Abrignani S., Siena S., Nicolantonio F.D., Bardelli A.
Clin Cancer Res. 2020 Mar 15;26(6):1372-1384. doi: 10.1158/1078-0432.CCR-19-2409. Epub 2019 Dec 12.
[31831554] - ATR expands embryonic stem cell fate potential in response to replication stress
Atashpaz S., Shams S.S., Gonzalez J.M., Sebestyén E., Arghavanifard N., Gnocchi A., Albers E., Minardi S., Faga G., Soffientini P., Allievi E., Cancila V., Bachi A., Fernández-Capetillo Ó., Tripodo C., Ferrari F., López-Contreras A.J., Costanzo V.
Elife. 2020 Mar 12;9:e54756. doi: 10.7554/eLife.54756.
[32163370] - Intracellular transports and atherogenesis
Mironov A.A., Sesorova I.S., Dimov I.D., Karelina N.R., Beznoussenko G.V.
Front Biosci (Landmark Ed). 2020 Mar 1;25:1230-1258.
[32114431] - Reciprocal regulation between alternative splicing and the DNA damage response
Cambindo Botto A.E., Muñoz J.C., Giono L.E., Nieto-Moreno N., Cuenca C., Kornblihtt A.R., Muñoz M.J.
Genet Mol Biol. 2020 Mar 27;43(1 suppl. 1):e20190111. doi: 10.1590/1678-4685-GMB-2019-0111. eCollection 2020.
[32236390] - Cancer risks associated with germline PALB2 pathogenic variants: An international study of 524 families
Yang X., Leslie G., Doroszuk A., Schneider S., Allen J., Decker B., Dunning A.M., Redman J., Scarth J., Plaskocinska I., Luccarini C., Shah M., Pooley K., Dorling L., Leei A., Adank M.A., Adlard J., Aittomäki K., Andrulis I.L., Ang P., Barwell J., Bernstein J.L., Bobolis K., Borg Å., Blomqvist C., Claes K.B.M., Concannon P., Cuggia A., Culver J.O., Damiola F., De Pauw A., Diez O., Dolinsky J.S., Domchek S.M., Engel C., Evans D.G., Fostira F., Garber J., Golmard L., Goode E.L., Gruber S.B., Hahnen E., Hake C., Heikkinen T., Hurley J.E., Janavicius R., Kleibl Z., Kleiblova P., Konstantopoulou I., Kvist A., Laduca H., Lee A.S.G., Lesueur F., Maher E.R., Mannermaa A., Manoukian S., McFarland R., McKinnon W., Meindl A., Metcalfe K., Taib N.A.M., Moilanen J., Nathanson K.L., Neuhausen S., Ng P.S., Nguyen-Dumont T., Nielsen S.M., Obermair F., Offit K., Olopade O.I., Ottini L., Penkert J., Pylkäs K., Radice P., Ramus S.J., Rudaitis V., Side L., Silva-Smith R., Silvestri V., Skytte A.-B., Slavin T., Soukupova J., Tondini C., Trainer A.H., Unzeitig G., Usha L., Van Overeem Hansen T., Whitworth J., Wood M., Yip C.H., Yoon S.-Y., Yussuf A., Zogopoulos G., Goldgar D., Hopper J.L., Chenevix-Trench G., Pharoah P., George S.H.L., Balmaña J., Houdayer C., James P., El-Haffaf Z., Ehrencrona H., Janatova M., Peterlongo P., Nevanlinna H., Schmutzler R., Teo S.-H., Robson M., Pal T., Couch F., Weitzel J.N., Elliott A., Southey M., Winqvist R., Easton D.F., Foulkes W.D., Antoniou A.C., Tischkowitz M.
J Clin Oncol. 2020 Mar 1;38(7):674-685. doi: 10.1200/JCO.19.01907. Epub 2019 Dec 16.
[31999646] - Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib
Bagnolini G., Milano D., Manerba M., Schipani F., Ortega J.A., Gioia D., Falchi F., Balboni A., Farabegoli F., De Franco F., Robertson J., Pellicciari R., Pallavicini I., Peri S., Minucci S., Girotto S., Di Stefano G., Roberti M., Cavalli A.
J Med Chem. 2020 Mar 12;63(5):2588-2619. doi: 10.1021/acs.jmedchem.9b01526. Epub 2020 Feb 24.
[32037829] - SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development
Falbo L., Raspelli E., Romeo F., Fiorani S., Pezzimenti F., Casagrande F., Costa I., Parazzoli D., Costanzo V.
Nat Commun. 2020 Mar 12;11(1):1345. doi: 10.1038/s41467-020-15180-5.
[32165637] - Early fate of exogenous promoters in E. coli
Yousuf M., Iuliani I., Veetil R.T., Seshasayee A.S.N., Sclavi B., Cosentino Lagomarsino M.
Nucleic Acids Res. 2020 Mar 18;48(5):2348-2356. doi: 10.1093/nar/gkz1196.
[31960057] - Reproducibility warning: The curious case of polyethylene glycol 6000 and spheroid cell culture
Serrati S., Martinelli C., Palazzo A., Iacobazzi R.M., Perrone M., Ong Q.K., Luo Z., Bekdemir A., Pinto G., Cavalleri O., Cutrignelli A., Laquintana V., Denora N., Stellacci F., Krol S.
PLoS One. 2020 Mar 19;15(3):e0224002. doi: 10.1371/journal.pone.0224002. eCollection 2020.
[32191706] - Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness
Patel V.L., Busch E.L., Friebel T.M., Cronin A., Leslie G., McGuffog L., Adlard J., Agata S., Agnarsson B.A., Ahmed M., Aittom K., Alducci E., Andrulis I.L., Arason A., Arnold N., Artioli G., Arver B., Auber B., Azzollini J., Balmaña J., Barkardottir R.B., Barnes D.R., Barroso A., Barrowdale D., Belotti M., Benitez J., Bertelsen B., Blok M.J., Bodrogi I., Bonadona V., Bonanni B., Bondavalli D., Boonen S.E., Borde J., Borg A., Bradbury A.R., Brady A., Brewer C., Brunet J., Buecher B., Buys S.S., Cabezas-Camarero S., Caldes T., Caliebe A., Caligo M.A., Calvello M., Campbell I.G., Carnevali I., Carrasco E., Chan T.L., Chu A.T.W., Chung W.K., Claes K.B.M., Cook J., Cortesi L., Couch F.J., Daly M.B., Damante G., Darder E., Davidson R., De La Hoya M., Della Puppa L., Dennis J., Díez O., Ding Y.C., Ditsch N., Domchek S.M., Donaldson A., Dworniczak B., Easton D.F., Eccles D.M., Eeles R.A., Ehrencrona H., Ejlertsen B., Engel C., Evans D.G., Faivre L., Faust U., Feliubadalo L., Foretova L., Fostira F., Fountzilas G., Frost D., García-Barberan V., Garre P., Gauthier-Villars M., Geczi L., Gehrig A., Gerdes A.-M., Gesta P., Giannini G., Glendon G., Godwin A.K., Goldgar D.E., Greene M.H., Gutierrez-Barrera A.M., Hahnen E., Hamann U., Hauke J., Herold N., Hogervorst F.B.L., Honisch E., Hopper J.L., Hulick P.J., Izatt L., Jager A., James P., Janavicius R., Jensen U.B., Jensen T.D., Johannsson O.Th., John E.M., Joseph V., Kang E., Kast K., Kiiski J.I., Kim S.-W., Kim Z., Ko K.-P., Konstantopoulou I., Kramer G., Krogh L., Kruse T.A., Kwong A., Larsen M., Lasset C., Lautrup C., Lazaro C., Lee J., Lee J.W., Lee M.H., Lemke J., Lesueur F., Liljegren A., Lindblom A., Llovet P., Lopez-Fernandez A., Lopez-Perolio I., Lorca V., Loud J.T., Ma E.S.K., Mai P.L., Manoukian S., Mari V., Martin L., Matricardi L., Mebirouk N., Medici V., Meijers-Heijboer H.E.J., Meindl A., Mensenkamp A.R., Miller C., Gomes D.M., Montagna M., Mooij T.M., Moserle L., Mouret-Fourme E., Mulligan A.M., Nathanson K.L., Navratilova M., Nevanlinna H., Niederacher D., Cilius Nielsen F.C., Nikitina-Zake L., Offit K., Olah E., Olopade O.I., Ong K.-R., Osorio A., Ott C.-E., Palli D., Park S.K., Parsons M.T., Pedersen I.S., Peissel B., Peixoto A., Perez-Segura P., Peterlongo P., Petersen A.H., Porteous M.E., Pujana M.A., Radice P., Ramser J., Rantala J., Rashid M.U., Rhiem K., Rizzolo P., Robson M.E., Rookus M.A., Rossing C.M., Ruddy K.J., Santos C., Saule C., Scarpitta R., Schmutzler R.K., Schuster H., Senter L., Seynaeve C.M., Shah P.D., Sharma P., Shin V.Y., Silvestri V., Simard J., Singer C.F., Skytte A.-B., Snape K., Solano A.R., Soucy P., Southey M.C., Spurdle A.B., Steele L., Steinemann D., Stoppa-Lyonnet D., Stradella A., Sunde L., Sutter C., Tan Y.Y., Teixeira M.R., Teo S.H., Thomassen M., Tibiletti M.G., Tischkowitz M., Tognazzo S., Toland A.E., Tommasi S., Torres D., Toss A., Trainer A.H., Tung N., Van Asperen C.J., Van Der Baan F.H., Van Der Kolk L.E., Van Der Luijt R.B., Van Hest L.P., Varesco L., Varon-Mateeva R., Viel A., Vierstrate J., Villa R., Von Wachenfeldt A., Wagner P., Wang-Gohrke S., Wappenschmidt B., Weitzel J.N., Wieme G., Yadav S., Yannoukakos D., Yoon S.-Y., Zanzottera C., Zorn K.K., D’Amico A.V., Freedman M.L., Pomerantz M.M., Chenevix-Trench G., Antoniou A.C., Neuhausen S.L., Ottini L., Nielsen H.R., Rebbeck T.R.
Cancer Res. 2020 Feb 1;80(3):624-638. doi: 10.1158/0008-5472.CAN-19-1840. Epub 2019 Nov 13.
[31723001] - Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Ercilla A., Benada J., Amitash S., Zonderland G., Baldi G., Somyajit K., Ochs F., Costanzo V., Lukas J., Toledo L.
Cell Rep. 2020 Feb 18;30(7):2416-2429.e7. doi: 10.1016/j.celrep.2020.01.067.
[32075739] - SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability
Rossi F., Helbling-Leclerc A., Kawasumi R., Jegadesan N.K., Xu X., Devulder P., Abe T., Takata M., Xu D., Rosselli F., Branzei D.
EMBO Rep. 2020 Feb 5;21(2):e48222. doi: 10.15252/embr.201948222. Epub 2019 Dec 23.
[31867888] - MRI-based radiomics signature for localized prostate cancer: a new clinical tool for cancer aggressiveness prediction? Sub-study of prospective phase II trial on ultra-hypofractionated radiotherapy (AIRC IG-13218)
Gugliandolo S.G., Pepa M., Isaksson L.J., Marvaso G., Raimondi S., Botta F., Gandini S., Ciardo D., Volpe S., Riva G., Rojas D.P., Zerini D., Pricolo P., Alessi S., Petralia G., Summers P.E., Mistretta F.A., Luzzago S., Cattani F., De Cobelli O., Cassano E., Cremonesi M., Bellomi M., Orecchia R., Jereczek-Fossa B.A.
Eur Radiol. 2021 Feb;31(2):716-728. doi: 10.1007/s00330-020-07105-z. Epub 2020 Aug 27.
[32852590] - Plasma miRNA-based signatures in CRC screening programs
Zanutto S., Ciniselli C.M., Belfiore A., Lecchi M., Masci E., Delconte G., Primignani M., Tosetti G., Dal Fante M., Fazzini L., Airoldi A., Vangeli M., Turpini F., Rubis Passoni G.G., Viaggi P., Arena M., Motta R.I.O., Cantù A.M., Crosta C., De Roberto G., Iannuzzi F., Cassinotti A., Dall'Olio V., Tizzoni L., Sozzi G., Meroni E., Bisanti L., Pierotti M.A., Verderio P., Gariboldi M.
Int J Cancer. 2020 Feb 15;146(4):1164-1173. doi: 10.1002/ijc.32573. Epub 2019 Aug 5.
[31304978] - The clustering of mapoe anti-amyloidogenic peptide on nanoparticle surface does not alter its performance in controlling beta-amyloid aggregation
Corti R., Cox A., Cassina V., Nardo L., Salerno D., Marrano C.A., Missana N., Andreozzi P., Silva P.J., Stellacci F., Dal Magro R., Re F., Mantegazza F.
Int J Mol Sci. 2020 Feb 5;21(3):1066. doi: 10.3390/ijms21031066.
[32033502] - High-dose Vitamin C enhances cancer immunotherapy
Magrì A., Germano G., Lorenzato A., Lamba S., Chilà R., Montone M., Amodio V., Ceruti T., Sassi F., Arena S., Abrignani S., D’Incalci M., Zucchetti M., Di Nicolantonio F., Bardelli A.
Sci Transl Med. 2020 Feb 26;12(532):eaay8707. doi: 10.1126/scitranslmed.aay8707.
[32102933] - Squeezing in a Meal: Myosin Functions in Phagocytosis
Barger S.R., Gauthier N.C., Krendel M.
Trends Cell Biol. 2020 Feb;30(2):157-167. doi: 10.1016/j.tcb.2019.11.002. Epub 2019 Dec 10.
[31836280] - The spectrum of fancm protein truncating variants in European breast cancer cases
Figlioli G., Kvist A., Tham E., Soukupova J., Kleiblova P., Muranen T.A., Andrieu N., Azzollini J., Balmaña J., Barroso A., Benítez J., Bertelsen B., Blanco A., Bonanni B., Borg Å., Brunet J., Calistri D., Calvello M., Chvojka S., Cortesi L., Darder E., Del Valle J., Diez O., Eon-Marchais S., Fostira F., Gensini F., Houdayer C., Janatova M., Kiiski J.I., Konstantopoulou I., Kubelka-Sabit K., Lázaro C., Lesueur F., Manoukian S., Marcinkute R., Mickys U., Moncoutier V., Myszka A., Nguyen-Dumont T., Nielsen F.C., Norvilas R., Olah E., Osorio A., Papi L., Peissel B., Peixoto A., Plaseska-Karanfilska D., Pócza T., Rossing M., Rudaitis V., Santamariña M., Santos C., Smichkoska S., Southey M.C., Stoppa-Lyonnet D., Teixeira M., Törngren T., Toss A., Urioste M., Vega A., Vlckova Z., Yannoukakos D., Zampiga V., Kleibl Z., Radice P., Nevanlinna H., Ehrencrona H., Janavicius R., Peterlongo P., ENIGMA Consortium
Cancers (Basel). 2020 Jan 26;12(2):292. doi: 10.3390/cancers12020292.
[31991861] - CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells
Brenna E., Davydov A.N., Ladell K., McLaren J.E., Bonaiuti P., Metsger M., Ramsden J.D., Gilbert S.C., Lambe T., Price D.A., Campion S.L., Chudakov D.M., Borrow P., McMichael A.J.
Cell Rep. 2020 Jan 7;30(1):137-152.e5. doi: 10.1016/j.celrep.2019.12.016.
[31914381] - Linking cancer transcriptional addictions by CDK7 to YAP/TAZ
Piccolo S.
Genes Dev. 2020 Jan 1;34(1-2):4-6. doi: 10.1101/gad.335562.119.
[31896688] - Searching for the Source of Difference: A Graphical Model Approach
Djordjilović V., Chiogna M., Romualdi C., Salviato E.
January 2020 DOI: 10.1007/978-3-030-34585-3_12
In book: Computational Intelligence Methods for Bioinformatics and Biostatistics (pp.131-138) - Listeria monocytogenes exploits host caveolin for cell-to-cell spreading
Dhanda A.S., Yu C., Lulic K.T., Vogl A.W., Rausch V., Yang D., Nichols B.J., Kim S.H., Polo S., Hansen C.G., Guttman J.A.
mBio. 2020 Jan 21;11(1):e02857-19. doi: 10.1128/mBio.02857-19.
[31964732] - 2D Gel Electrophoresis to Detect DNA Replication and Recombination Intermediates in Budding Yeast
Zardoni L., Nardini E., Liberi G.
Methods Mol Biol. 2020;2119:43-59. doi: 10.1007/978-1-0716-0323-9_4.
[31989513] - Negative supercoil at gene boundaries modulates gene topology
Achar Y.J., Adhil M., Choudhary R., Gilbert N., Foiani M.
Nature. 2020 Jan;577(7792):701-705. doi: 10.1038/s41586-020-1934-4. Epub 2020 Jan 22.
[31969709] - A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Escala-Garcia M., Abraham J., Andrulis I.L., Anton-Culver H., Arndt V., Ashworth A., Auer P.L., Auvinen P., Beckmann M.W., Beesley J., Behrens S., Benitez J., Bermisheva M., Blomqvist C., Blot W., Bogdanova N.V., Bojesen S.E., Bolla M.K., Børresen-Dale A.-L., Brauch H., Brenner H., Brucker S.Y., Burwinkel B., Caldas C., Canzian F., Chang-Claude J., Chanock S.J., Chin S.-F., Clarke C.L., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Dennis J., Devilee P., Dunn J.A., Dunning A.M., Dwek M., Earl H.M., Eccles D.M., Eliassen A.H., Ellberg C., Evans D.G., Fasching P.A., Figueroa J., Flyger H., Gago-Dominguez M., Gapstur S.M., García-Closas M., García-Sáenz J.A., Gaudet M.M., George A., Giles G.G., Goldgar D.E., González-Neira A., Grip M., Guénel P., Guo Q., Haiman C.A., Håkansson N., Hamann U., Harrington P.A., Hiller L., Hooning M.J., Hopper J.L., Howell A., Huang C.-S., Huang G., Hunter D.J., Jakubowska A., John E.M., Kaaks R., Kapoor P.M., Keeman R., Kitahara C.M., Koppert L.B., Kraft P., Kristensen V.N., Lambrechts D., Le Marchand L., Lejbkowicz F., Lindblom A., Lubiński J., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Martinez M.E., Maurer T., Mavroudis D., Meindl A., Milne R.L., Mulligan A.M., Neuhausen S.L., Nevanlinna H., Newman W.G., Olshan A.F., Olson J.E., Olsson H., Orr N., Peterlongo P., Petridis C., Prentice R.L., Presneau N., Punie K., Ramachandran D., Rennert G., Romero A., Sachchithananthan M., Saloustros E., Sawyer E.J., Schmutzler R.K., Schwentner L., Scott C., Simard J., Sohn C., Southey M.C., Swerdlow A.J., Tamimi R.M., Tapper W.J., Teixeira M.R., Terry M.B., Thorne H., Tollenaar R.A.E.M., Tomlinson I., Troester M.A., Truong T., Turnbull C., Vachon C.M., van der Kolk L.E., Wang Q., Winqvist R., Wolk A., Yang X.R., Ziogas A., Pharoah P.D.P., Hall P., Wessels L.F.A., Chenevix-Trench G., Bader G.D., Dörk T., Easton D.F., Canisius S., Schmidt M.K.
Nat Commun. 2020 Jan 16;11(1):312. doi: 10.1038/s41467-019-14100-6.
[31949161] - A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Escala-Garcia M., Abraham J., Andrulis I.L., Anton-Culver H., Arndt V., Ashworth A., Auer P.L., Auvinen P., Beckmann M.W., Beesley J., Behrens S., Benitez J., Bermisheva M., Blomqvist C., Blot W., Bogdanova N.V., Bojesen S.E., Bolla M.K., Børresen-Dale A.-L., Brauch H., Brenner H., Brucker S.Y., Burwinkel B., Caldas C., Canzian F., Chang-Claude J., Chanock S.J., Chin S.-F., Clarke C.L., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Dennis J., Devilee P., Dunn J.A., Dunning A.M., Dwek M., Earl H.M., Eccles D.M., Eliassen A.H., Ellberg C., Evans D.G., Fasching P.A., Figueroa J., Flyger H., Gago-Dominguez M., Gapstur S.M., García-Closas M., García-Sáenz J.A., Gaudet M.M., George A., Giles G.G., Goldgar D.E., González-Neira A., Grip M., Guénel P., Guo Q., Haiman C.A., Håkansson N., Hamann U., Harrington P.A., Hiller L., Hooning M.J., Hopper J.L., Howell A., Huang C.-S., Huang G., Hunter D.J., Jakubowska A., John E.M., Kaaks R., Kapoor P.M., Keeman R., Kitahara C.M., Koppert L.B., Kraft P., Kristensen V.N., Lambrechts D., Le Marchand L., Lejbkowicz F., Lindblom A., Lubiński J., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Martinez M.E., Maurer T., Mavroudis D., Meindl A., Milne R.L., Mulligan A.M., Neuhausen S.L., Nevanlinna H., Newman W.G., Olshan A.F., Olson J.E., Olsson H., Orr N., Peterlongo P., Petridis C., Prentice R.L., Presneau N., Punie K., Ramachandran D., Rennert G., Romero A., Sachchithananthan M., Saloustros E., Sawyer E.J., Schmutzler R.K., Schwentner L., Scott C., Simard J., Sohn C., Southey M.C., Swerdlow A.J., Tamimi R.M., Tapper W.J., Teixeira M.R., Terry M.B., Thorne H., Tollenaar R.A.E.M., Tomlinson I., Troester M.A., Truong T., Turnbull C., Vachon C.M., van der Kolk L.E., Wang Q., Winqvist R., Wolk A., Yang X.R., Ziogas A., Pharoah P.D.P., Hall P., Wessels L.F.A., Chenevix-Trench G., Bader G.D., Dörk T., Easton D.F., Canisius S., Schmidt M.K.
Nat Commun. 2020 Jan 16;11(1):312. doi: 10.1038/s41467-019-14100-6.
[31949161] - Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Fachal L., Aschard H., Beesley J., Barnes D.R., Allen J., Kar S., Pooley K.A., Dennis J., Michailidou K., Turman C., Soucy P., Lemaçon A., Lush M., Tyrer J.P., Ghoussaini M., Marjaneh M.M., Jiang X., Agata S., Aittomäki K., Alonso M.R., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arason A., Arndt V., Aronson K.J., Arun B.K., Auber B., Auer P.L., Azzollini J., Balmaña J., Barkardottir R.B., Barrowdale D., Beeghly-Fadiel A., Benitez J., Bermisheva M., Bialkowska K., Blanco A.M., Blomqvist C., Blot W., Bogdanova N.V., Bojesen S.E., Bolla M.K., Bonanni B., Borg A., Bosse K., Brauch H., Brenner H., Briceno I., Brock I.W., Brooks-Wilson A., Brüning T., Burwinkel B., Buys S.S., Cai Q., Caldés T., Caligo M.A., Camp N.J., Campbell I., Canzian F., Carroll J.S., Carter B.D., Castelao J.E., Chiquette J., Christiansen H., Chung W.K., Claes K.B.M., Clarke C.L., Mari V., Berthet P., Castera L., Vaur D., Lallaoui H., Bignon Y.-J., Uhrhammer N., Bonadona V., Lasset C., Révillion F., Vennin P., Muller D., Gomes D.M., Ingster O., Coupier I., Pujol P., Collonge-Rame M.-A., Mortemousque I., Bera O., Rose M., Baurand A., Bertolone G., Faivre L., Dreyfus H., Leroux D., Venat-Bouvet L., Bézieau S., Delnatte C., Chiesa J., Gilbert-Dussardier B., Gesta P., Prieur F.P., Bronner M., Sokolowska J., Coulet F., Boutry-Kryza N., Calender A., Giraud S., Leone M., Fert-Ferrer S., Stoppa-Lyonnet D., Jiao Y., Lesueur F.L., Mebirouk N., Barouk-Simonet E., Bubien V., Longy M., Sevenet N., Gladieff L., Toulas C., Reimineras A., Sobol H., Paillerets B.B.-D., Cabaret O., Caron O., Guillaud-Bataille M., Rouleau E., Belotti M., Buecher B., Caputo S., Colas C., Pauw A.D., Fourme E., Gauthier-Villars M., Golmard L., Moncoutier V., Saule C., Donaldson A., Murray A., Brady A., Brewer C., Pottinger C., Miller C., Gallagher D., Gregory H., Cook J., Eason J., Adlard J., Barwell J., Ong K.-R., Snape K., Walker L., Izatt L., Side L., Tischkowitz M., Rogers M.T., Porteous M.E., Ahmed M., Morrison P.J., Brennan P., Eeles R., Davidson R., Collée J.M., Cornelissen S., Couch F.J., Cox A., Cross S.S., Cybulski C., Czene K., Daly M.B., de la Hoya M., Devilee P., Diez O., Ding Y.C., Dite G.S., Domchek S.M., Dörk T., dos-Santos-Silva I., Droit A., Dubois S., Dumont M., Duran M., Durcan L., Dwek M., Eccles D.M., Engel C., Eriksson M., Evans D.G., Fasching P.A., Fletcher O., Floris G., Flyger H., Foretova L., Foulkes W.D., Friedman E., Fritschi L., Frost D., Gabrielson M., Gago-Dominguez M., Gambino G., Ganz P.A., Gapstur S.M., Garber J., García-Sáenz J.A., Gaudet M.M., Georgoulias V., Giles G.G., Glendon G., Godwin A.K., Goldberg M.S., Goldgar D.E., González-Neira A., Tibiletti M.G., Greene M.H., Grip M., Gronwald J., Grundy A., Guénel P., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Harrington P.A., Hartikainen J.M., Hartman M., He W., Healey C.S., Heemskerk-Gerritsen B.A.M., Heyworth J., Hillemanns P., Hogervorst F.B.L., Hollestelle A., Hooning M.J., Hopper J.L., Howell A., Huang G., Hulick P.J., Imyanitov E.N., Sexton A., Christian A., Trainer A., Spigelman A., Fellows A., Shelling A., Fazio A.D., Blackburn A., Crook A., Meiser B., Patterson B., Clarke C., Saunders C., Hunt C., Scott C., Amor D., Marsh D., Edkins E., Salisbury E., Haan E., Neidermayr E., Macrea F., Farshid G., Lindeman G., Trench G., Mann G., Gill G., Thorne H., Hickie I., Winship I., Flanagan J., Kollias J., Visvader J., Stone J., Burke J., Saunus J., Forbes J., Kirk J., French J., Tucker K., Wu K., Phillips K., Lipton L., Andrews L., Lobb L., Kentwell M., Spurdle M., Cummings M., Gleeson M., Harris M., Jenkins M., Young M.A., Delatycki M., Wallis M., Burgess M., Price M., Brown M., Southey M.C., Bogwitz M., Field M., Friedlander M., Gattas M., Saleh M., Hayward N., Pachter N., Cohen P., Duijf P., James P., Simpson P., Fong P., Butow P., Williams R., Kefford R., Scott R., Milne R., Balleine R., Dawson S.–J., Lok S., O’Connell S., Greening S., Nightingale S., Edwards S.L., Fox S., McLachlan S.-A., Lakhani S., Antill Y., Aalfs C., Meijers-Heijboer H., van Engelen K., Gille H., Boere I., Collée M., van Deurzen C., Obdeijn I.-M., van den Ouweland A., Seynaeve C.M., Siesling S., Verloop J., van Asperen C.J., van Cronenburg T., Blok R., de Boer M., Garcia E.G., Adank M., Hogervorst F., Jenner D., van Leeuwen F., Rookus M., Russell N., Schmidt M., van den Belt-Dusebout S., Kets C., Mensenkamp A., de Bock T., van der Hout A., Mourits M., Oosterwijk J., Ausems M., Koudijs M., Baxter R., Yip D., Carpenter J., Davis A., Pathmanathan N., Graham D., Sachchithananthan M., Isaacs C., Iwasaki M., Jager A., Jakimovska M., Jakubowska A., James P.A., Janavicius R., Jankowitz R.C., John E.M., Johnson N., Jones M.E., Jukkola-Vuorinen A., Jung A., Kaaks R., Kang D., Kapoor P.M., Karlan B.Y., Keeman R., Kerin M.J., Khusnutdinova E., Kiiski J.I., Kirk J., Kitahara C.M., Ko Y.-D., Konstantopoulou I., Kosma V.-M., Koutros S., Kubelka-Sabit K., Kwong A., Kyriacou K., Laitman Y., Lambrechts D., Lee E., Leslie G., Lester J., Lesueur F., Lindblom A., Lo W.-Y., Long J., Lophatananon A., Loud J.T., Lubinski J., MacInnis R.J., Maishman T., Makalic E., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Martinez M.E., Matsuo K., Maurer T., Mavroudis D., Mayes R., McGuffog L., McLean C., Meindl A., Miller A., Miller N., Montagna M., Moreno F., Muir K., Mulligan A.M., Muñoz-Garzon V.M., Muranen T.A., Narod S.A., Nassir R., Nathanson K.L., Neuhausen S.L., Nevanlinna H., Neven P., Nielsen F.C., Nikitina-Zake L., Norman A., Offit K., Olah E., Olopade O.I., Olsson H., Orr N., Osorio A., Pankratz V.S., Papp J., Park S.K., Park-Simon T.-W., Parsons M.T., Paul J., Pedersen I.S., Peissel B., Peshkin B., Peterlongo P., Peto J., Plaseska-Karanfilska D., Prajzendanc K., Prentice R., Presneau N., Prokofyeva D., Pujana M.A., Pylkäs K., Radice P., Ramus S.J., Rantala J., Rau-Murthy R., Rennert G., Risch H.A., Robson M., Romero A., Rossing M., Saloustros E., Sánchez-Herrero E., Sandler D.P., Santamariña M., Sawyer E.J., Scheuner M.T., Schmidt D.F., Schmutzler R.K., Schneeweiss A., Schoemaker M.J., Schöttker B., Schürmann P., Scott C., Scott R.J., Senter L., Shah M., Sharma P., Shen C.-Y., Shu X.-O., Singer C.F., Slavin T.P., Smichkoska S., Spinelli J.J., Spurdle A.B., Sutter C., Swerdlow A.J., Tamimi R.M., Tan Y.Y., Tapper W.J., Taylor J.A., Teixeira M.R., Tengström M., Teo S.H., Terry M.B., Teulé A., Thomassen M., Thull D.L., Toland A.E., Tollenaar R.A.E.M., Tomlinson I., Torres D., Torres-Mejía G., Troester M.A., Truong T., Tung N., Tzardi M., Ulmer H.-U., Vachon C.M., van der Kolk L.E., van Rensburg E.J., Vega A., Viel A., Vijai J., Vogel M.J., Wang Q., Wappenschmidt B., Weinberg C.R., Weitzel J.N., Wendt C., Wildiers H., Winqvist R., Wolk A., Wu A.H., Yannoukakos D., Zhang Y., Zheng W., Hunter D., Pharoah P.D.P., Chang-Claude J., García-Closas M., Schmidt M.K., Milne R.L., Kristensen V.N., French J.D., Antoniou A.C., Chenevix-Trench G., Simard J., Easton D.F., Dunning A.M., GEMO Study Collaborators, EMBRACE Collaborators, KConFab Investigators, HEBON Investigators, ABCTB Investigators
Nat Genet. 2020 Jan;52(1):56-73. doi: 10.1038/s41588-019-0537-1. Epub 2020 Jan 7.
[31911677]
Research programs
Researchers
