Publications 2021
last update sept 2022
- HnRNP? K mislocalisation is a no vel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing
Alexander Bampton, Ariana Gatt, Jack Humphrey, Sara Cappelli, Dipanjan Bhattacharya, Sandrine Foti, Anna-Leigh Brown, Yasmine Asi, Yi Hua Low, Marco Foiani, Towfique Raj, Emanuele Buratti, Pietro Fratta & Tammaryn Lashley
Acta Neuropathologica volume 142, pages609–627 (2021)
[34274995] - Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
Baxter J.S., Johnson N., Tomczyk K., Gillespie A., Maguire S., Brough R., Fachal L., Michailidou K., Bolla M.K., Wang Q., Dennis J., Ahearn T.U., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arndt V., Aronson K.J., Augustinsson A., Becher H., Beckmann M.W., Behrens S., Benitez J., Bermisheva M., Bogdanova N.V., Bojesen S.E., Brenner H., Brucker S.Y., Cai Q., Campa D., Canzian F., Castelao J.E., Chan T.L., Chang-Claude J., Chanock S.J., Chenevix-Trench G., Choi J.-Y., Clarke C.L., Colonna S., Conroy D.M., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Devilee P., Dörk T., Dossus L., Dwek M., Eccles D.M., Ekici A.B., Eliassen A.H., Engel C., Fasching P.A., Figueroa J., Flyger H., Gago-Dominguez M., Gao C., García-Closas M., García-Sáenz J.A., Ghoussaini M., Giles G.G., Goldberg M.S., González-Neira A., Guénel P., Gu?ndert M., Haeberle L., Hahnen E., Haiman C.A., Hall P., Hamann U., Hartman M., Hatse S., Hauke J., Hollestelle A., Hoppe R., Hopper J.L., Hou M.-F., Ito H., Iwasaki M., Jager A., Jakubowska A., Janni W., John E.M., Joseph V., Jung A., Kaaks R., Kang D., Keeman R., Khusnutdinova E., Kim S.-W., Kosma V.-M., Kraft P., Kristensen V.N., Kubelka-Sabit K., Kurian A.W., Kwong A., Lacey J.V., Lambrechts D., Larson N.L., Larsson S.C., Le Marchand L., Lejbkowicz F., Li J., Long J., Lophatananon A., L ubi?ski J., Mannermaa A., Manoochehri M., Manoukian S., Margolin S., Matsuo K., Mavroudis D., Mayes R., Menon U., Milne R.L., Mohd Taib N.A., Muir K., Muranen T.A., Murphy R.A., Nevanlinna H., O’Brien K.M., Offit K., Olson J.E., Olsson H., Park S.K., Park-Simon T.-W., Patel A.V., Peterlongo P., Peto J., Plaseska-Karanfilska D., Presneau N., Pylkäs K., Rack B., Rennert G., Romero A., Ruebner M., Ru?diger T., Saloustros E., Sandler D.P., Sawyer E.J., Schmidt M.K., Schmutzler R.K., Schneeweiss A., Schoemaker M.J., Shah M., Shen C.-Y., Shu X.-O., Simard J., Southey M.C., Stone J., Surowy H., Swerdlow A.J., Tamimi R.M., Tapper W.J., Taylor J.A., Teo S.H., Teras L.R., Terry M.B., Toland A.E., Tomlinson I., Truong T., Tseng C.-C., Untch M., Vachon C.M., van den Ouweland A.M.W., Wang S.S., Weinberg C.R., Wendt C., Winham S.J., Winqvist R., Wolk A., Wu A.H., Yamaji T., Zheng W., Ziogas A., Pharoah P.D.P., Dunning A.M., Easton D.F., Pettitt S.J., Lord C.J., Haider S., Orr N., Fletcher O., NBCS Collaborators, kConFab Investigators, ABCTB
Am J Hum Genet. 2021 Jul 1;108(7):1190-1203. doi: 10.1016/j.ajhg.2021.05.013. Epub 2021 Jun 18.
[34146516] - The interplay between mitochondrial functionality and genome integrity in the prevention of human neurologic diseases
D’Errico M., Parlanti E., Pascucci B., Filomeni G., Mastroberardino P.G., Dogliotti E.
Arch Biochem Biophys. 2021 Oct 15;710:108977. Doi10.1016/j.abb.2021.108977. Epub 2021 Jun 24.
[34174223] - Overloading of differentiated Caco-2 cells during lipid transcytosis induces glycosylation mistakes in the Golgi complex
Denisova G.N., Dimov I.D., Zaitseva A.V., Artiux L.J., Mironov A.A., Karelina N.R.
Vol.45, No.3,2021, pp.773-783,doi: 10.32604/BIOCELL.2021.014233
[014233] - APOBEC3B is preferentially expressed at the G2/M phase of cell cycle
Hirabayashi S., Shirakawa K., Horisawa Y., Matsumoto T., Matsui H., Yamazaki H., Sarca A.D., Kazuma Y., Nomura R., Konishi Y., Takeuchi S., Stanford E., Kawaji H., Murakawa Y., Takaori- Kondo A.
Biochem Biophys Res Commun. 2021 Mar 26;546:178-184. doi:10.1016/j.bbrc.2021.02.008. Epub 2021 Feb 13.
[33592502] - Epigenetic regulation of replication origin assembly: A role for histone H1 and chromatin remodeling factors
Falbo L., Costanzo V.
Bioessays. 2021 Jan;43(1):e2000181. doi: 10.1002/bies.202000181. Epub 2020 Nov 9.
[33165968] - Role of Cdkn2a in the Emery-Dreifuss Muscular Dystrophy Cardiac Phenotype
Pegoli G., Milan M., Manti P.G., Bianchi A., Lucini F., Santarelli P., Bearzi C., Rizzi R., Lanzuolo C.
Biomolecules. 2021 Apr 6;11(4):538. doi: 10.3390/biom11040538.
[33917623] - Towards population-based genetic screenings for breast and ovarian cancer: A comprehensive review from economic evaluations to patient perspectives
Ficarazzi F., Vecchi M., Ferrari M., Pierotti M.A.
BREAST. 2021 Aug;58:121-129. doi: 10.1016/j.breast.2021.04.011. Epub 2021 May 12.
[34022715] - Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Morra A., Escala-Garcia M., Beesley J., Keeman R., Canisius S., Ahearn T.U., Andrulis I.L., Anton- Culver H., Arndt V., Auer P.L., Augustinsson A., Beane Freeman L.E., Becher H., Beckmann M.W., Behrens S., Bojesen S.E., Bolla M.K., Brenner H., Bru?ning T., Buys S.S., Caan B., Campa D., Canzian F., Castelao J.E., Chang-Claude J., Chanock S.J., Cheng T.-Y.D., Clarke C.L., Colonna S.V., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Dennis J., Dörk T., Dossus L., Dunning A.M., Dwek M., Eccles D.M., Ekici A.B., Eliassen A.H., Eriksson M., Evans D.G., Fasching P.A., Flyger H., Fritschi L., Gago-Dominguez M., García-Sáenz J.A., Giles G.G., Grip M., Guénel P., Gu?ndert M., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Hart S.N., Hartikainen J.M., Hartmann A., He W., Hooning M.J., Hoppe R., Hopper J.L., Howell A., Hunter D.J., Jager A., Jakubowska A., Janni W., John E.M., Jung A.Y., Kaaks R., Keupers M., Kitahara C.M., Koutros S., Kraft P., Kristensen V.N., Kurian A.W., Lacey J.V., Lambrechts D., Le Marchand L., Lindblom A., Linet M., Luben R.N., Lubi?ski J., Lush M., Mannermaa A., Manoochehri M., Margolin S., Martens J.W.M., Martinez M.E., Mavroudis D., Michailidou K., Milne R.L., Mulligan A.M., Muranen T.A., Nevanlinna H., Newman W.G., Nielsen S.F., Nordestgaard B.G., Olshan A.F., Olsson H., Orr N., Park-Simon T.-W., Patel A.V., Peissel B., Peterlongo P., Plaseska-Karanfilska D., Prajzendanc K., Prentice R., Presneau N., Rack B., Rennert G., Rennert H.S., Rhenius V., Romero A., Roylance R., Ruebner M., Saloustros E., Sawyer E.J., Schmutzler R.K., Schneeweiss A., Scott C., Shah M., Smichkoska S., Southey M.C., Stone J., Surowy H., Swerdlow A.J., Tamimi R.M., Tapper W.J., Teras L.R., Terry M.B., Tollenaar R.A.E.M., Tomlinson I., Troester M.A., Truong T., Vachon C.M., Wang Q., Hurson A.N., Winqvist R., Wolk A., Ziogas A., Brauch H., García-Closas M., Pharoah P.D.P., Easton D.F., Chenevix-Trench G., Schmidt M.K., NBCS Collaborators, ABCTB Investigators, kConFab Investigators
Breast Cander Res.2021 Aug 18;23(1):86. doi: 10.1186/s13058-021-01450-7.
[s13058-021-01450-7] - Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to ne oadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013- 14) trial
Park H.A., Neumeyer S., Michailidou K., Bolla M.K., Wang Q., Dennis J., Ahearn T.U., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arndt V., Aronson K.J., Augustinsson A., Baten A., Beane Freeman L.E., Becher H., Beckmann M.W., Behrens S., Benitez J., Bermisheva M., Bogdanova N.V., Bojesen S.E., Brauch H., Brenner H., Brucker S.Y., Burwinkel B., Campa D., Canzian F., Castelao J.E., Chanock S.J., Chenevix-Trench G., Clarke C.L., Børresen-Dale A.-L., Grenaker Alnæs G.I., Sahlberg K.K., Ottestad L., Kåresen R., Schlichting E., Holmen M.M., Sauer T., Haakensen V., Engebråten O., Naume B., Fosså A., Kiserud C.E., Reinertsen K.V., Helland Å., Riis M., Geisler J., Conroy D.M., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Devilee P., Dörk T., dos-Santos- Silva I., Dwek M., Eccles D.M., Eliassen A.H., Engel C., Eriksson M., Evans D.G., Fasching P.A., Flyger H., Fritschi L., García-Closas M., García-Sáenz J.A., Gaudet M.M., Giles G.G., Glendon G., Goldberg M.S., Goldgar D.E., González-Neira A., Grip M., Guénel P., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Han S., Harkness E.F., Hart S.N., He W., Heemskerk-Gerritsen B.A.M., Hopper J.L., Hunter D.J., Clarke C., Marsh D., Scott R., Baxter R., Yip D., Carpenter J., Davis A., Pathmanathan N., Simpson P., Graham D., Sachchithananthan M., Amor D., Andrews L., Antill Y., Balleine R., Beesley J., Bennett I., Bogwitz M., Botes L., Brennan M., Brown M., Buckley M., Burke J., Butow P., Caldon L., Campbell I., Chauhan D., Chauhan M., Chenevix-Trench G., Christian A., Cohen P., Colley A., Crook A., Cui J., Cummings M., Dawson S.-J., DeFazio? A., Delatycki M., Dickson R., Dixon J., Edkins T., Edwards S., Farshid G., Fellows A., Fenton G., Field M., Flanagan J., Fong P., Forrest L., Fox S., French J., Friedlander M., Gaff C., Gattas M., George P., Greening S., Harris M., Hart S., Hayward N., Hopper J., Hoskins C., Hunt C., James P., Jenkins M., Kidd A., Kirk J., Koehler J., Kollias J., Lakhani S., Lawrence M., Lindeman G., Lipton L., Lobb L., Mann G., Marsh D., McLachlan? S.A., Meiser B., Milne R., Nightingale S., O’Connell S., O’Sullivan S., Ortega D.G., Pachter N., Patterson B., Pearn A., Phillips K., Pieper E., Rickard E., Robinson B., Saleh M., Salisbury E., Saunders C., Saunus J., Scott R., Scott C., Sexton A., Shelling A., Simpson P., Southey M., Spurdle A., Taylor J., Taylor R., Thorne H., Trainer A., Tucker K., Visvader J., Walker L., Williams R., Winship I., Young M.A., Jager A., Jakubowska A., John E.M., Jung A., Kaaks R., Kapoor P.M., Keeman R., Khusnutdinova E., Kitahara C.M., Koppert L.B., Koutros S., Kristensen 108 109 V.N., Kurian A.W., Lacey J., Lambrechts D., Le Marchand L., Lo W.-Y., Lubi?ski J., Mannermaa A., Manoochehri M., Margolin S., Martinez M.E., Mavroudis D., Meindl A., Menon U., Milne R.L., Muranen T.A., Nevanlinna H., Newman W.G., Nordestgaard B.G., Offit K., Olshan A.F., Olsson H., Park-Simon T.-W., Peterlongo P., Peto J., Plaseska-Karanfilska D., Presneau N., Radice P., Rennert G., Rennert H.S., Romero A., Saloustros E., Sawyer E.J., Schmidt M.K., Schmutzler R.K., Schoemaker M.J., Schwentner L., Scott C., Shah M., Shu X.-O., Simard J., Smeets A., Southey M.C., Spinelli J.J., Stevens V., Swerdlow A.J., Tamimi R.M., Tapper W.J., Taylor J.A., Terry M.B., Tomlinson I., Troester M.A., Truong T., Vachon C.M., van Veen E.M., Vijai J., Wang S., Wendt C., Winqvist R., Wolk A., Ziogas A., Dunning A.M., Pharoah P.D.P., Easton D.F., Zheng W., Kraft P., Chang-Claude J., NBCS Collaborators, ABCTB Investigators, kConFab Investigators
Br J Cancer 2021 Oct;125(8):1135-1145.doi: 10.1038/s41416-021-01432-8. Epub 2021 Aug 2.
[ 33179154] - Mendelian randomisation study of smoking exposure in relation to breast cancer risk
Park H.A., Neumeyer S., Michailidou K., Bolla M.K., Wang Q., Dennis J., Ahearn T.U., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arndt V., Aronson K.J., Augustinsson A., Baten A., Beane Freeman L.E., Becher H., Beckmann M.W., Behrens S., Benitez J., Bermisheva M., Bogdanova N.V., Bojesen S.E., Brauch H., Brenner H., Brucker S.Y., Burwinkel B., Campa D., Canzian F., Castelao J.E., Chanock S.J., Chenevix-Trench G., Clarke C.L., Børresen-Dale A.-L., Grenaker Alnæs G.I., Sahlberg K.K., Ottestad L., Kåresen R., Schlichting E., Holmen M.M., Sauer T., Haakensen V., Engebråten O., Naume B., Fosså A., Kiserud C.E., Reinertsen K.V., Helland Å., Riis M., Geisler J., Conroy D.M., Couch F.J., Cox A., Cross S.S., Czene K., Daly M.B., Devilee P., Dörk T., dos-Santos-Silva I., Dwek M., Eccles D.M., Eliassen A.H., Engel C., Eriksson M., Evans D.G., Fasching P.A., Flyger H., Fritschi L., García-Closas M., García-Sáenz J.A., Gaudet M.M., Giles G.G., Glendon G., Goldberg M.S., Goldgar D.E., González-Neira A., Grip M., Guénel P., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Han S., Harkness E.F., Hart S.N., He W., Heemskerk-Gerritsen B.A.M., Hopper J.L., Hunter D.J., Clarke C., Marsh D., Scott R., Baxter R., Yip D., Carpenter J., Davis A., Pathmanathan N., Simpson P., Graham D., Sachchithananthan M., Amor D., Andrews L., Antill Y., Balleine R., Beesley J., Bennett I., Bogwitz M., Botes L., Brennan M., Brown M., Buckley M., Burke J., Butow P., Caldon L., Campbell I., Chauhan D., Chauhan M., Chenevix-Trench G., Christian A., Cohen P., Colley A., Crook A., Cui J., Cummings M., Dawson S.-J., DeFazio? A., Delatycki M., Dickson R., Dixon J., Edkins T., Edwards S., Farshid G., Fellows A., Fenton G., Field M., Flanagan J., Fong P., Forrest L., Fox S., French J., Friedlander M., Gaff C., Gattas M., George P., Greening S., Harris M., Hart S., Hayward N., Hopper J., Hoskins C., Hunt C., James P., Jenkins M., Kidd A., Kirk J., Koehler J., Kollias J., Lakhani S., Lawrence M., Lindeman G., Lipton L., Lobb L., Mann G., Marsh D., McLachlan? S.A., Meiser B., Milne R., Nightingale S., O’Connell S., O’Sullivan S., Ortega D.G., Pachter N., Patterson B., Pearn A., Phillips K., Pieper E., Rickard E., Robinson B., Saleh M., Salisbury E., Saunders C., Saunus J., Scott R., Scott C., Sexton A., Shelling A., Simpson P., Southey M., Spurdle A., Taylor J., Taylor R., Thorne H., Trainer A., Tucker K., Visvader J., Walker L., Williams R., Winship I., Young M.A., Jager A., Jakubowska A., John E.M., Jung A., Kaaks R., Kapoor P.M., Keeman R., Khusnutdinova E., Kitahara C.M., Koppert L.B., Koutros S., Kristensen V.N., Kurian A.W., Lacey J., Lambrechts D., Le Marchand L., Lo W.-Y., Lubi?ski J., Mannermaa A., Manoochehri M., Margolin S., Martinez M.E., Mavroudis D., Meindl A., Menon U., Milne R.L., Muranen T.A., Nevanlinna H., Newman W.G., Nordestgaard B.G., Offit K., Olshan A.F., Olsson H., Park-Simon T.-W., Peterlongo P., Peto J., Plaseska-Karanfilska D., Presneau N., Radice P., Rennert G., Rennert H.S., Romero A., Saloustros E., Sawyer E.J., Schmidt M.K., Schmutzler R.K., Schoemaker M.J., Schwentner L., Scott C., Shah M., Shu X.-O., Simard J., Smeets A., Southey M.C., Spinelli J.J., Stevens V., Swerdlow A.J., Tamimi R.M., Tapper W.J., Taylor J.A., Terry M.B., Tomlinson I., Troester M.A., Truong T., Vachon C.M., van Veen E.M., Vijai J., Wang S., Wendt C., Winqvist R., Wolk A., Ziogas A., Dunning A.M., Pharoah P.D.P., Easton D.F., Zheng W., Kraft P., Chang-Claude J., NBCS Collaborators, ABCTB Investigators, kConFab Investigators
2021 British Journal of Cancer 125 8 1135 1145 10.1038/s41416-021-01432-8
[s41416-021-01432-8] - CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
Johnson N., Maguire S., Morra A., Kapoor P.M., Tomczyk K., Jones M.E., Schoemaker M.J., Gilham C., Bolla M.K., Wang Q., Dennis J., Ahearn T.U., Andrulis I.L., Anton-Culver H., Antonenkova N.N., Arndt V., Aronson K.J., Augustinsson A., Baynes C., Freeman L.E.B., Beckmann M.W., Benitez J., Bermisheva M., Blomqvist C., Boeckx B., Bogdanova N.V., Bojesen S.E., Brauch H., Brenner H., Burwinkel B., Campa D., Canzian F., Castelao J.E., Chanock S.J., Chenevix-Trench G., Clarke C.L., Børresen-Dale A.-L., Alnæs G.I.G., Sahlberg K.K., Ottestad L., Kåresen R., Schlichting E., Holmen M.M., Sauer T., Haakensen V., Engebråten O., Naume B., Fosså A., Kiserud C.E., Reinertsen K.V., Helland Å., Riis M., Geisler J., Conroy D.M., Couch F.J., Cox A., Cross S.S., Czene K., Dörk T., Eliassen A.H., Engel C., Evans D.G., Fasching P.A., Figueroa J., Floris G., Flyger H., Gago-Dominguez M., Gapstur S.M., García-Closas M., Gaudet M.M., Giles G.G., Goldberg M.S., González-Neira A., Bowtell D.D.L., deFazio A., Webb P.M., Guénel P., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Harrington P.A., Hart S.N., Hooning M.J., Hopper J.L., Howell A., Hunter D.J., Clarke C., Marsh D., Scott R., Baxter R., Yip D., Carpenter J., Davis A., Pathmanathan N., Simpson P., Graham D., Sachchithananthan M., Amor D., Andrews L., Antill Y., Balleine R., Beesley J., Bennett I., Bogwitz M., Botes L., Brennan M., Brown M., Buckley M., Burke J., Butow P., Caldon L., Campbell I., Chauhan D., Chauhan M., Christian A., Cohen P., Colley A., Crook A., Cui J., Cummings M., Dawson S.-J., Delatycki M., Dickson R., Dixon J., Edkins T., Edwards S., Farshid G., Fellows A., Fenton G., Field M., Flanagan J., Fong P., Forrest L., Fox S., French J., Friedlander M., Gaff C., Gattas M., George P., Greening S., Harris M., Hart S., Hayward N., Hopper J., Hoskins C., Hunt C., James P., Jenkins M., Kidd A., Kirk J., Koehler J., Kollias J., Lakhani S., Lawrence M., Lindeman G., Lipton L., Lobb L., Mann G., Marsh D., McLachlan? S.A., Meiser B., Milne R.L., Nightingale S., O’Connell S., O’Sullivan S., Ortega D.G., Pachter N., Patterson B., Pearn A., Phillips K., Pieper E., Rickard E., Robinson B., Saleh M., Salisbury E., Saunders C., Saunus J., Scott C., Sexton A., Shelling A., Simpson P., Southey M.C., Spurdle A., Taylor J., Taylor R., Thorne H., Trainer A., Tucker K., Visvader J., Walker L., Williams R., Winship I., Young M.A., Jager A., Jakubowska A., Jakubowska A., Kaaks R., Keeman R., Khusnutdinova E., Khusnutdinova E., Kitahara C.M., Kosma V.-M., Koutros S., Kraft P., Kristensen V.N., Kurian A.W., Lambrechts D., Le Marchand L., Linet M., Lubi?ski J., Mannermaa A., Manoukian S., Mar golin S., Martens J.W.M., Mavroudis D., Mayes R., Meindl A., Neuhausen S.L., Nevanlinna H., Newman W.G., Nielsen S.F., Nordestgaard B.G., Obi N., Olshan A.F., Olson J.E., Olsson H., Orban E., Park- Simon T.-W., Peterlongo P., Plaseska-Karanfilska D., Pylkäs K., Rennert G., Rennert H.S., Ruddy K.J., Saloustros E., Sandler D.P., Sawyer E.J., Schmutzler R.K., Scott C., Shu X.-O., Simard J., Smichkoska S., Sohn C., Spinelli J.J., Stone J., Tamimi R.M., Taylor J.A., Tollenaar R.A.E.M., Tomlinson I., Troester M.A., Truong T., Vachon C.M., van Veen E.M., Wang S.S., Weinberg C.R., Wendt C., Wildiers H., Winqvist R., Wolk A., Zheng W., Ziogas A., Dunning A.M., Pharoah P.D.P., Easton D.F., Howie A.F., Peto J., dos-Santos-Silva I., Swerdlow A.J., Chang-Claude J., Schmidt M.K., Orr N., Fletcher O., NBCS Collaborators, AOCS Group, ABCTB Investigators, kConFab Investigators
Br J Cancer 2021 Feb;124(4):842-854.doi: 10.1038/s41416-020-01185-w. Epub 2021 Jan 26.
[s41416-020-01185-w] - Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver
Bertocchi A., Carloni S., Ravenda P.S., Bertalot G., Spadoni I., Lo Cascio A., Gandini S., Lizier M., Braga D., Asnicar F., Segata N., Klaver C., Brescia P., Rossi E., Anselmo A., Guglietta S., Maroli A., Spaggiari P., Tarazona N., Cervantes A., Marsoni S., Lazzari L., Jodice M.G., Luise C., Erreni M., Pece S., Di Fiore P.P., Viale G., Spinelli A., Pozzi C., Penna G., Rescigno M.
Cancer Cell 2021 May 10;39(5):708-724.e11.doi: 10.1016/j.ccell.2021.03.004. Epub 2021 Apr 1.
[33798472] - CD4 T Cell-Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair-Deficient Tumors
Germano G., Lu S., Rospo G., Lamba S., Rousseau B., Fanelli S., Stenech D., Le D.T., Hays J., Totaro M.G., Amodio V., Chilà R., Mondino A., Diaz L.A., Di Nicolantonio F., Bardelli A.
Cancer Discov.2021 Jul;11(7):1844-1859. doi: 10.1158/2159-8290.CD-20-0987. Epub 2021 Mar 2.
[33653693] - T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models
Morello G., Cancila V., La Rosa M., Germano G., Lecis D., Amodio V., Zanardi F., Iannelli F., Greco D., La Paglia L., Fiannaca A., Urso A.M., Graziano G., Ferrari F., Pupa S.M., Sangaletti S., Chiodoni C., Pruneri G., Bardelli A., Colombo M.P., Tripodo C.
Cancer Immunol Res. 2021 Jul;9(7):825-837. doi: 10.1158/2326-6066.CIR-20-0645. Epub 2021 May 3.
[33941587] - Myeloid cell heterogeneity in lung cancer: implication for immunotherapy
Sangaletti S., Ferrara R., Tripodo C., Garassino M.C., Colombo M.P.
Cancer Immunol Immunother 2021 Sep;70(9):2429-2438. doi: 10.1007/s00262-021-02916-5. Epub 2021 Apr 2.
[33797567] - Targeting lipid metabolism is an emerging strategy to enhance the efficacy of anti-HER2 therapies in HER2-positive breast cancer
Ligorio F., Pellegrini I., Castagnoli L., Vingiani A., Lobefaro R., Zattarin E., Santamaria M., Pupa S.M., Pruneri G., de Braud F., Vernieri C.
Cancer Lett. 2021 Jul 28;511:77-87.doi: 10.1016/j.canlet.2021.04.023. Epub 2021 May 5.
[33961924] - Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer
Di Modica M., Gargari G., Regondi V., Bonizzi A., Arioli S., Belmonte B., De Cecco L., Fasano E., Bianchi F., Bertolotti A., Tripodo C., Villani L., Corsi F., Guglielmetti S., Balsari A., Triulzi T., Tagliabue E.
Cancer Res. 2021 Apr 15;81(8):2195-2206. doi: 10.1158/0008-5472.CAN-20-1659. Epub 2021 Jan 22.
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Pupa S.M., Ligorio F., Cancila V., Franceschini A., Tripodo C., Vernieri C., Castagnoli L.
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Cancers (Basel) 2021 Sep 13;13(18):4587. doi: 10.3390/cancers13184587.
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Amodio V., Mauri G., Reilly N.M., Sar tore?bianchi A., Siena S., Bardelli A., Germano G.
Cancers (Basel) 2021 May 27;13(11):2638. doi: 10.3390/cancers13112638.
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Ligorio F., Fucà G., Zattarin E., Lobefaro R., Zambelli L., Leporati R., Rea C., Mariani G., Bianchi G.V., Capri G., de Braud F., Vernieri C.
Cancers (Basel) 2021 Apr 19;13(8):1964.doi: 10.3390/cancers13081964.
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Cell. 2021 Sep 30;184(20):5230-5246.e22.doi: 10.1016/j.cell.2021.08.035. Epub 2021 Sep 21.
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Cell Death Differ 2021 May;28(5) 1720-1732. doi: 10.1038/s41418-020-00698-4. Epub 2020 Dec 16.
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Cell Metab 2021 Nov 2;33(11) 2247-2259.e6.doi: 10.1016/j.cmet.2021.10.008.
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Cell Rep 2021 Sep 14;36(11):109694. doi: 10.1016/j.celrep.2021.109694.
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Cell Stress. 2021 Oct 29;5(11):167-172. doi: 10.15698/cst2021.11.258. eCollection 2021 Nov.
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Cells Dev. 2021 Dec; 168:203736. doi: 10.1016/j.cdev.2021.203736. Epub 2021 Aug 26.
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Circulation. 2021 Nov 16;144(20):1629-1645.doi: 10.1161/CIRCULATIONAHA.121.054182. Epub 2021 Oct 12
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Clin Cancer Res. 2021 Jun 15;27(12) 3443-3455.doi: 10.1158/1078-0432.CCR-20-4928. Epub 2021 Mar 30.
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Clin Infect Dis. 2021 Nov 16;73(10):1860-1870. doi: 10.1093/cid/ciab216.
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Dev Cell 2021 Oct 25;56(20):2841-2855.e8. doi: 10.1016/j.devcel.2021.09.007. Epub 2021 Sep 23.
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Dev Cell 2021 Sep 27;56(18):2607-2622.e6.doi: 10.1016/j.devcel.2021.08.019. Epub 2021 Sep 16.
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EClinicalMedicine? 2021 Aug 28;40:101101. doi: 10.1016/j.eclinm.2021.101101. eCollection 2021 Oct.
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Elife 2021 Oct 6;10:e67495.doi: 10.7554/eLife.67495.
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Elife 2021 Oct 28;10:e68627.doi: 10.7554/eLife.68627.
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Elife 2021 May 20;10:e63542.doi: 10.7554/eLife.63542.
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EMBO REP 2021 May 5;22(5):e51412.doi: 10.15252/embr.202051412. Epub 2021 Mar 12.
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Eur J Immunol. 2021 Dec;51(12):3243-3246.doi: 10.1002/eji.202149315. Epub 2021 Sep 28.
[34528258] - MRI-based radiomics signature for localized prostate cancer: a new clinical tool for cancer aggressiveness prediction? Sub-study of prospective phase II trial on ultra-hypofractionated radiotherapy (AIRC IG-13218)
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Eur Radiol 2021 Feb;31(2):716-728. doi: 10.1007/s00330-020-07105-z. Epub 2020 Aug 27.
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Exp Dermatol 2022 Apr;31(4):608-614.doi: 10.1111/exd.14499. Epub 2021 Nov 16.
[34758172] - Tailoring Cellular Function: The Contribution of the Nucleus in Mechanotransduction
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Front Bioeng Biotechnol 2021 Jan 8;8:596746.doi: 10.3389/fbioe.2020.596746. eCollection 2020.
[33490050] - HGF and MET: From Brain Development to Neurological Disorders
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Front Cell Dev Biol 2021 Jun 9;9:683609.doi: 10.3389/fcell.2021.683609. eCollection 2021.
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Front Cell Dev Biol Fron2021 Feb 18;9:637565.doi: 10.3389/fcell.2021.637565. eCollection 2021.
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Front Cell Dev Biol 2021 Jan 28;8:625717. doi: 10.3389/fcell.2020.625717. eCollection 2020.
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Front Chem 2021 Feb 25;9:598802. doi: 10.3389/fchem.2021.598802. eCollection 2021.
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Front Genet 2021 Feb 10;12:606630. doi: 10.3389/fgene.2021.606630. eCollection 2021.
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Front Immunol 2021 Dec 3;12:775151. doi: 10.3389/fimmu.2021.775151. eCollection 2021.
[34925346] - Amplifying Tumor-Stroma Communication: An Emerging Oncogenic Function of Mutant p53
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Front Oncol. 2021 Jan 11;10:614230.doi: 10.3389/fonc.2020.614230. eCollection 2020.
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Genes Dis 2020 Dec 30;8(6):798-813. doi: 10.1016/j.gendis.2020.12.008. eCollection 2021 Nov.
[34522709] - The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant
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[34113011] - Single-cell profiling reveals the dynamics of cytomegalovirus-specific T cells in haploidentical hematopoietic stem cell transplantation
van Beek J.J.P., Roberto A., Puccio S., de Paoli F., Graziano G., Salviato E., Alvisi G., Zanon V., Scarpa A., Zaghi E., Calvi M., Di Vito C., Mineri R., Sarina B., de Philippis C., Santoro A., Mariotti J., Bramanti S., Ferrari F., Castagna L., Mavilio D., Lugli E.
Haematologica 2021 Oct 1;106(10):2768-2773. doi: 10.3324/haematol.2020.276352.
[34233445] - Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer
Kar S.P., Considine D.P.C., Tyrer J.P., Plummer J.T., Chen S., Dezem F.S., Barbeira A.N., Rajagopal P.S., Rosenow W.T., Moreno F., Bodelon C., Chang-Claude J., Chenevix-Trench G., deFazio A., Dörk T., Ekici A.B., Ewing A., Fountzilas G., Goode E.L., Hartman M., Heitz F., Hillemanns P., Høgdall E., Høgdall C.K., Huzarski T., Jensen A., Karlan B.Y., Khusnutdinova E., Kiemeney L.A., Kjaer S.K., Klapdor R., Köbel M., Li J., Liebrich C., May T., Olsson H., Permuth J.B., Peterlongo P., Radice P., Ramus S.J., Riggan M.J., Risch H.A., Saloustros E., Simard J., Szafron L.M., Titus L., Thompson C.L., Vierkant R.A., Winham S.J., Zheng W., Doherty J.A., Berchuck A., Lawrenson K., Im H.K., Manichaikul A.W., Pharoah P.D.P., Gayther S.A., Schildkraut J.M.
HGG Adv 2021 Jul 8;2(3):100042.doi: 10.1016/j.xhgg.2021.100042. Epub 2021 Jun 16.
[34317694] - Exploring the association with disease recurrence of miRNAs predictive of colorectal cancer
Zanutto S., Ciniselli C.M., Belfiore A., Dall’Olio V., Tizzoni L., Varinelli L., Pierotti M.A., Battaglia L., Verderio P., Guaglio M., Gariboldi M.
Int J Biol markers 2022 Mar;37(1):102-109.doi: 10.1177/17246008211064915. Epub 2021 Dec 21.
[34931559] - Multi-Gene Testing Overview with a Clinical Perspective in Metastatic Triple-Negative Breast Cancer
Dameri M., Ferrando L., Cirmena G., Vernieri C., Pruneri G., Ballestrero A., Zoppoli G.
Int J Mol Sci 2021 Jul 1;22(13):7154.doi: 10.3390/ijms22137154.
[34281208] - Detecting Variants in the NBN Gene While Testing for Hereditary Breast Cancer: What to Do Next?
Zuntini R., Bonora E., Pradella L.M., Amato L.B., Vidone M., De Fanti S., Catucci I., Cortesi L., Medici V., Ferrari S., Gasparre G., Peterlongo P., Sazzini M., Turchetti D.
Int. J Mol Sci 2021 May 29;22(11):5832. doi: 10.3390/ijms22115832
[34072463] - MET Exon 14 Skipping: A Case Study for the Detection of Genetic Variants in Cancer Driver Genes by Deep Learning
Nosi V., Luca A., Milan M., Arigoni M., Benvenuti S., Cacchiarelli D., Cesana M., Riccardo S., Filippo L.D., Cordero F., Beccuti M., Comoglio P.M., Calogero R.A.
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[33921709] - A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
Mentegari E., Bertoletti F., Kissova M., Zucca E., Galli S., Tagliavini G., Garbelli A., Maffia A., Bione S., Ferrari E., Di Fagagna F.D., Francia S., Sabbioneda S., Chen L.-Y., Lingner J., Bergoglio V., Hoffmann J.-S., Hu?bscher U., Crespan E., Maga G.
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[33673424] - Empowering Clinical Decision Making in Oligometastatic Colorectal Cancer: The Potential Role of Drug Screening of Patient-Derived Organoids
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[34327296] - Low-Dose Aspirin in High-Risk Individuals With S creen-Detected Subsolid Lung Nodules: A Randomized Phase II Trial
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JNCI Cancer Spectr 2020 Oct 20;4(6):pkaa096.doi: 10.1093/jncics/pkaa096. eCollection 2020 Dec.
[33409459] - Oncolytic adenovirus and gene therapy with EphA?2-BiTE? for the treatment of pediatric highgrade gliomas
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J Immunother Cancer 2021 May;9(5):e001930. doi: 10.1136/jitc-2020-001930.
[33963009] - Activation of Src family kinase ameliorates secretory trafficking in mutant prion protein cells
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[33662396] - COPII collar defines the boundary between ER and ER exit site and does not coat car go containers
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J Cell Biol 2021 Jun 7;220(6):e201907224. doi: 10.1083/jcb.201907224.
[33852719] - A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition
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[34338295] - DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining
Cabrini M., Roncador M., Galbiati A., Cipolla L., Maffia A., Iannelli F., Sabbioneda S., d’Adda di Fagagna F., Francia S.
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[33558311] - Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation
Osana S., Kitajima Y., Suzuki N., Nunomiya A., Takada H., Kubota T., Murayama K., Nagatomi R.
J Cell Physiol 2021 Jul;236(7):5293-5305.doi: 10.1002/jcp.30237. Epub 2020 Dec 30.
[jcp.30237] - MEIS1 in Hematopoiesis and Cancer. How MEIS1-PBX Interaction Can Be Used in Therapy
Blasi F., Bruckmann C.
J Dev Biol 2021 Oct 13;9(4):44.doi: 10.3390/jdb9040044.
[34698191] - The emerging role of β-secretases in cancer
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[33926496] - Anti-Interleukin-10 Unleashes Transcriptional Response to Leishmanial Antigens in Visceral Leishmaniasis Patients
Singh O.P., Syn G., Nylén S., Engwerda C., Sacks D., Wilson M.E., Kumar R., Chakravarty J., Sundar S., Blackwell J.M., Fakiola M.
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[32614452] - Urinary proteomics reveals key markers of salt sensitivity in hypertensive patients during saline infusion
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J Nephrol 2021 Jun;34(3):739-751. doi: 10.1007/s40620-020-00877-z. Epub 2021 Jan 4.
[33398797] - Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
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[34834440] - Clinical Indicators of Moribundity in Swine Experimentally Inoculated with African Swine Fever Virus
Hershey B.J., Hagart J.L., Havas K.A.
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[33198851] - Sex and Adverse Events of Adjuvant Chemotherapy in Colon Cancer: An Analysis of 34 640 Patients in the ACCENT Database
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J Nati Cancer Inst 2021 Apr 6;113(4):400-407.doi: 10.1093/jnci/djaa124.
[32835356] - Strategies to Prevent or Remediate Cancer and Treatment-Related Aging
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J Nail Cancer Inst 2021 Feb 1;113(2):112-122.doi: 10.1093/jnci/djaa060.
[32348501] - CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model
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J Virol 2021 Jan 27;95(8):e02394-20.doi: 10.1128/JVI.02394-20. Online ahead of print.
[33504604] - Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene
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[34187875] - Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse
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Metabolism 2021 Mar;116:154463.doi: 10.1016/j.metabol.2020.154463. Epub 2020 Dec 10.
[33309713] - Opti-nQL: An Optimized, Versatile and Sensitive Nano-LC Method for MS-Based Lipidomics Analysis
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Metabolites 2021 Oct 21;11(11):720. doi: 10.3390/metabo11110720.
[34822378] - Missing Value Monitoring to Address Missing Values in Quantitative Proteomics.
Matafora V., Bachi A.
Methods in Molecular Biology (Clifton, N.J.), 01 Jan 2021, 2228:401-408 DOI: 10.1007/978-1-0716- 1024-4_27
[33950505] - Preparing Map of Chromosome Territory Distribution Frequency.
Nasta?y P., Maiuri P.
Methods in Molecular Biology (Clifton, N.J.), 01 Jan 2021, 2157:213-219 DOI: 10.1007/978-1-0716- 0664-3_12
[32820406] - REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.
Taglialatela A., Leuzzi G., Sannino V., Cuella-Martin R., Huang J.-W., Wu-Baer F., Baer R., Costanzo V., Ciccia A.
Molecular Cell, 10 Sep 2021, 81(19):4008-4025.e7 DOI: 10.1016/j.molcel.2021.08.016
[34508659] - Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.
Pellicanò G., Al Mamun M., Jurado-Santiago D., Villa-Hernández S., Yin X., Giannattasio M., Lanz M.C., Smolka M.B., Yeeles J., Shirahige K., García-Díaz M., Bermejo R.
Molecular Cell, 30 Apr 2021, 81(13):2778-2792.e4 DOI: 10.1016/j.molcel.2021.04.006
[33932350] - Reversibly Modulating the Blood-Brain Barrier by Laser Stimulation of Molecular-Targeted Nanoparticles.
Li X., Vemireddy V., Cai Q., Xiong H., Kang P., Li X., Giannotta M., Hayenga H.N., Pan E., Sirsi S.R., Mateo C., Kleinfeld D., Greene C., Campbell M., Dejana E., Bachoo R., Qin Z.
Nano Letters, 13 Sep 2021, 21(22):9805-9815 DOI: 10.1021/acs.nanolett.1c02996
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Nature, 01 Apr 2021, 592(7852):E8 DOI: 10.1038/s41586-021-03287-8
[s41586-021-03287-8] - Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in Glioblastoma.
Castellan M., Guarnieri A., Fujimura A., Zanconato F., Battilana G., Panciera T., Sladitschek H.L., Contessotto P., Citron A., Grilli A., Romano O., Bicciato S., Fassan M., Porcù E., Rosato A., Cordenonsi M., Piccolo S.
Nature Cancer, 07 Dec 2020, 2(2):174-188 DOI: 10.1038/s43018-020-00150-z
[33644767] - Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca P., Jäntti N.Z., Godbole R., Sommer C., Jacquemet G., Al-Akhrass H., Conway J.R.W., Kronqvist P., Kallionpää R.E., Oliveira-Ferrer L., Cervero P., Linder S., Aepfelbacher M., Zauber H., Rae J., Parton R.G., Disanza A., Scita G., Mayor S., Selbach M., Veltel S., Ivaska J.
Nature Cell Biology, 06 Oct 2021, 23(10):1073-1084 DOI: 10.1038/s41556-021-00767-x
[34616024] - Diet composition influences the metabolic benefits of short cycles of very low caloric intake.
Diaz-Ruiz A., Rhinesmith T., Pomatto-Watson L.C.D., Price N.L., Eshaghi F., Ehrlich M.R., Moats J.M., Carpenter M., Rudderow A., Brandhorst S., Mattison J.A., Aon M.A., Bernier M., Longo V.D., de Cabo R.
Nature Communications, 09 Nov 2021, 12(1):6463 DOI: 10.1038/s41467-021-26654-5
[6463] - Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.
Fajner V., Giavazzi F., Sala S., Oldani A., Martini E., Napoletano F., Parazzoli D., Cesare G., Cerbino R., Maspero E., Vaccari T., Polo S.
Nature Communications, 16 Sep 2021, 12(1):5488 DOI: 10.1038/s41467-021-25809-8
[5488 ] - Publisher Correction: Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis.
Sathe M., Muthukrishnan G., Rae J., Disanza A., Thattai M., Scita G., Parton R.G., Mayor S.
Nature Communications, 23 Aug 2021, 12(1):5158 DOI: 10.1038/s41467-021-25458-x
[5158] - A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis.
Pradella D., Deflorian G., Pezzotta A., Di Matteo A., Belloni E., Campolungo D., Paradisi A., Bugatti M., Vermi W., Campioni M., Chiapparino A., Scietti L., Forneris F., Giampietro C., Volf N., Rehman M., Zacchigna S., Paronetto M.P., Pistocchi A., Eichmann A., Mehlen P., Ghigna C..
Nature Communications, 11 Aug 2021, 12(1):4872 DOI: 10.1038/s41467-021-24998-6
[4872] - SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome.
Banfi F., Rubio A., Zaghi M., Massimino L., Fagnocchi G., Bellini E., Luoni M., Cancellieri C., Bagliani A., Di Resta C., Maffezzini C., Ianielli A., Ferrari M., Piazza R., Mologni L., Broccoli V., Sessa A.
Nature Communications, 30 Jun 2021, 12(1):4050 DOI: 10.1038/s41467-021-24391-3
[4050] - Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition.
Verginelli F., Pisacane A., Gambardella G., D’Ambrosio A., Candiello E., Ferrio M., Panero M., Casorzo L., Benvenuti S., Cascardi E., Senetta R., Geuna E., Ballabio A., Montemurro F., Sapino A., Comoglio P.M., Boccaccio C.
Nature Communications, 03 May 2021, 12(1):2498 DOI: 10.1038/s41467-021-22643-w
[2498] - Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ.
Della Chiara G., Gervasoni F., Fakiola M., Godano C., D’Oria C., Azzolin L., Bonnal R.J.P., Moreni G., Drufuca L., Rossetti G., Ranzani V., Bason R., De Simone M., Panariello F., Ferrari I., Fabbris T., Zanconato F., Forcato M., Romano O., Caroli J., Gruarin P., Sarnicola M.L., Cordenonsi M., Bardelli A., Zucchini N., Ceretti A.P., Mariani N.M., Cassingena A., Sartore-Bianchi A., Testa G., Gianotti L., Opocher E., Pisati F., Tripodo C., Macino G., Siena S., Bicciato S., Piccolo S., Pagani M.
Nature Communications, 20 Apr 2021, 12(1):2340 DOI: 10.1038/s41467-021-22544-y
[2340] - Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.
Agashe S., Joseph C.R., Reyes T.A.C., Menolfi D., Giannattasio M., Waizenegger A., Szakal B., Branzei D.
Nature Communications, 08 Apr 2021, 12(1):2111 DOI: 10.1038/s41467-021-22217-w
[2111] - Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
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Investigators, HEBON Investigators, ABCTB Investigators
Nature Communications, 14 May 2021, 12(1):2986DOI: 10.1038/s41467-021-23162-4
[33990587] - The human nucleoporin Tpr protects cells from RNA-mediated replication stress.
Kosar M., Giannattasio M., Piccini D., Maya-Mendoza A., García-Benítez F., Bartkova J., Barroso S.I., Gaillard H., Martini E., Restuccia U., Ramirez-Otero M.A., Garre M., Verga E., Andújar- Sánchez M., Maynard S., Hodny Z., Costanzo V., Kumar A., Bachi A., Aguilera A., Bartek J., Foiani M.
Nature Communications, 24 Jun 2021, 12(1):3937 DOI: 10.1038/s41467-021-24224-3
[3937] - A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
Coignard J., Lush M., Beesley J., O’Mara T.A., Dennis J., Tyrer J.P., Barnes D.R., McGuffog? L., Leslie G., Bolla M.K., Adank M.A., Agata S., Ahearn T., Aittomäki K., Andrulis I.L., Anton-Culver H., Arndt V., Arnold N., Aronson K.J., Arun B.K., Augustinsson A., Azzollini J., Barrowdale D., Baynes C., Becher H., Bermisheva M., Bernstein L., Bia?kowska K., Blomqvist C., Bojesen S.E., Bonanni B., Borg A., Brauch H., Brenner H., Burwinkel B., Buys S.S., Caldés T., Caligo M.A., Campa D., Carter B.D., Castelao J.E., Chang-Claude J., Chanock S.J., Chung W.K., Claes K.B.M., Clarke C.L., Bertrand O., Caputo S., Dupré A., Le Mentec M., Belotti M., Birot A.-M., Buecher B., Fourme E., Gauthier-Villars M., Golmard L., Houdayer C., Moncoutier V., de Pauw A., Saule C., Sinilnikova O., Mazoyer S., Damiola F., Barjhoux L., Verny-Pierre C., Léone M., Boutry-Kryza N., Calender A., Giraud S., Caron O., Guillaud-Bataille M., Bressac-de-Paillerets B., Bignon Y.-J., Uhrhammer N., Lasset C., Bonadona V., Berthet P., Vaur D., Castera L., Noguchi T., Popovici C., Sobol H., Bourdon V., Noguchi T., Remenieras A., Noguès C., Coupier I., Pujol P., Dumont A., Révillion F., Adenis C., Muller D., Barouk-Simonet E., Bonnet F., Bubien V., Sevenet N., Longy M., Toulas C., Guimbaud R., Gladieff L., Feillel V., Leroux D., Dreyfus H., Rebischung C., Peysselon M., Coron F., Faivre L., Baurand A., Jacquot C., Bertolone G., Lizard S., Prieur F., Lebrun M., Kientz C., Ferrer S.F., Mari V., Vénat-Bouvet L., Delnatte C., Bézieau S., Mortemousque I., Coulet F., Colas C., Soubrier F., Warcoin M., Sokolowska J., Bronner M., Collonge-Rame M.-A., Damette A., Gesta P., Lallaoui H., Chiesa J., Molina-Gomes D., Ingster O., Gregory H., Miedzybrodzka Z., Morrison P.J., Ong K.-R., Donaldson A., Rogers M.T., Kennedy M.J., Porteous M.E., Brewer C., Davidson R., Izatt L., Brady A., Barwell J., Adlard J., Foo C., Lalloo F., Side L.E., Eason J., Henderson A., Walker L., Eeles R.A., Cook J., Snape K., Eccles D.M., Murray A., McCann? 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Investigators, HEBON Investigators, ABCTB Investigators
Nature Communications, 2021, 12(1):1078 DOI: 10.1038/s41467-020-20496-3
[10.1038/s41467-020-20496-3] - Multi-domain translation between single-cell imaging and sequencing data using autoencoders.
Yang K.D., Belyaeva A., Venkatachalapathy S., Damodaran K., Katcoff A., Radhakrishnan A., Shivashankar G.V., Uhler C.
Nature Communications, 04 Jan 2021, 12(1):31 DOI: 10.1038/s41467-020-20249-2
[s41467-020-20249-2] - Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression
Bonnal R.J.P., Rossetti G., Lugli E., De Simone M., Gruarin P., Brummelman J., Drufuca L., Passaro M., Bason R., Gervasoni F., Della Chiara G., D’Oria C., Martinovic M., Curti S., Ranzani V., Cordiglieri C., Alvisi G., Mazza E.M.C., Oliveto S., Silvestri Y., Carelli E., Mazzara S., Bosotti R., Sarnicola M.L., Godano C., Bevilacqua V., Lorenzo M., Siena S., Bonoldi E., Sartore-Bianchi A., Amatu A., Veronesi G., Novellis P., Alloisio M., Giani A., Zucchini N., Opocher E., Ceretti A.P., Mariani N., Biffo S., Prati D., Bardelli A., Geginat J., Lanzavecchia A., Abrignani S., Pagani M.
Nature Immunology, 20 May 2021, 22(6):735-745 DOI: 10.1038/s41590-021-00930-4
[34017124] - Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan.
Mishra A., Mirzaei H., Guidi N., Vinciguerra M., Mouton A., Linardic M., Rappa F., Barone R., Navarrete G., Wei M., Brandhorst S., Di Biase S., Morgan T.E., Ram Kumar S., Conti P.S., Pellegrini M., Bernier M., de Cabo R., Longo V.D.
Nature Metabolism, 14 Oct 2021, 3(10):1342-1356 DOI: 10.1038/s42255-021-00469-6
[34650272] - Precision oncology in metastatic colorectal cancer - from biology to medicine.
Di Nicolantonio F., Vitiello P.P., Marsoni S., Siena S., Tabernero J., Trusolino L., Bernards R., Bardelli A.
Nature reviews. Clinical Oncology, 16 Apr 2021, 18(8):506-525 DOI: 10.1038/s41571-021-00495-z
[33864051] - Endocytosis in the context-dependent regulation of individual and collective cell properties.
Sigismund S., Lanzetti L., Scita G., Di Fiore P.P..
Nature reviews. Molecular Cell Biology, 01 Jun 2021, 22(9):625-643 DOI: 10.1038/s41580-021- 00375-5
[34075221] - Cellular senescence in ageing: from mechanisms to therapeutic opportunities.
Di Micco R., Krizhanovsky V., Baker D., d’Adda di Fagagna F.
Nature reviews. Molecular Cell Biology, 16 Dec 2020, 22(2):75-95 DOI: 10.1038/s41580-020- 00314-w
[33328614] - In Vitro Mechanobiology of Glioma: Mimicking the Brain Blood Vessels and White Matter Tracts Invasion Paths
Monzo P., Crestani M., Gauthier N.C.
January 2021DOI:10.1007/978-1-0716-0856-2_8 Brain Tumors (pp.159-196)
[978-1-0716-0856-2_8] - Mechano-Biological Features in a Patient-Specific Computational Model of Glioblastoma
Acerbi F., Agosti A., Falco J., Marchesi S., Vetrano I.G., DiMeco? F., Bizzi A., Ferroli P., Scita G., Ciarletta P.
October 2020 DOI:10.1007/978-1-0716-0856-2_12 In book: Brain Tumors, Neuromethods
[10.1007/978-1-0716-0856-2_12] - Protein truncating variants in FANCM and risk for ER-negative/triple negative breast cancer.
Peterlongo P., Figlioli G., Deans A.J., Couch F.J.
NPJ Breast Cancer, 28 Sep 2021, 7(1):130 DOI: 10.1038/s41523-021-00338-1
[s41523-021-00338-1] - Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions.
Zardoni L., Nardini E., Brambati A., Lucca C., Choudhary R., Loperfido F., Sabbioneda S., Liberi G.
Nucleic Acids Research, 01 Dec 2021, 49(22):12769-12784 DOI: 10.1093/nar/gkab1146
[34878142] - A rapid method to visualize human mitochondrial DNA replication through rotary shadowing and transmission electron microscopy.
Kosar M., Piccini D., Foiani M., Giannattasio M.
Nucleic Acids Research, 01 Dec 2021, 49(21):e121 DOI: 10.1093/nar/gkab770
[34500456] - Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer-target gene regulatory interactions.
Salviato E., Djordjilovi? V., Hariprakash J.M., Tagliaferri I., Pal K., Ferrari F.
Nucleic Acids Research, 01 Sep 2021, 49(17):e97 DOI: 10.1093/nar/gkab547
[6312759] - GSK-3 is an RNA polymerase II phospho-CTD kinase.
Moreno N.N., Villafañez F., Giono L.E., Cuenca C., Soria G., Muñoz M.J., Kornblihtt A.R.
Nucleic Acids Research, 01 Jun 2020, 48(11):6068-6080 DOI: 10.1093/nar/gkaa322
[32374842] - Aromatase Inhibitors in Postmenopausal Women with Hormone Receptor-Positive Breast Cancer: Profiles of Psychological Symptoms and Quality of Life in Different Patient Clusters
Borreani C., Alfieri S., Infante G., Miceli R., Mariani P., Bosisio M., Vernieri C., Bianchi G.V., Capri G..
Oncology, 29 Sep 2020, 99(2):84-95 DOI: 10.1159/000509651
[32992318] - PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity.
Poli A., Abdul-Hamid S., Zaurito A.E., Campagnoli F., Bevilacqua V., Sheth B., Fiume R., Pagani M., Abrignani S., Divecha N.
Proceedings of the National Academy of Sciences of the United States of America, 01 Aug 2021, 118(31):e2010053118 DOI: 10.1073/pnas.2010053118
[PMC8346797] - Threshold accumulation of a constitutive protein explains E. coli cell-division behavior in nutrient upshifts.
Panlilio M., Grilli J., Tallarico G., Iuliani I., Sclavi B., Cicuta P., Lagomarsino M.C.
Proceedings of the National Academy of Sciences of the United States of America, 01 May 2021, 118(18):e2016391118 DOI: 10.1073/pnas.2016391118
[33931503] - DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects.
Jegadesan N.K., Branzei D.
Proceedings of the National Academy of Sciences of the United States of America, 01 Apr 2021, 118(17):e2024258118 DOI: 10.1073/pnas.2024258118
[1073] - A DNA intercalating dye-based RT-qPCR alternative to diagnose SARS-CoV?-2..
Fuchs Wightman F., Godoy Herz M.A., Muñoz J.C., Stigliano J.N., Bragado L., Moreno N.N., Palavecino M., Servi L., Cabrerizo G., Clemente J., Avaro M., Pontoriero A., Benedetti E., Baumeister E., Rudolf F., Remes Lenicov F., Garcia C., Buggiano V., Kornblihtt A.R., Srebrow A., de la Mata M., Muñoz M.J., Schor I.E., Petrillo E.
RNA Biology, 26 May 2021, 18(12):2218-2225 DOI: 10.1080/15476286.2021.1926648
[33966602] - Computed structures of core eukaryotic protein complexes.
Humphreys I., Pei J., Baek M., Krishnakumar A., Anishchenko I., Ovchinnikov S., Zhang J., Ness T.J., Banjade S., Bagde S.R., Stancheva V.G., Li X.-H., Liu K., Zheng Z., Barrero D.J., Roy U., Kuper J., Fernández I.S., Szakal B., Branzei D., Rizo J., Kisker C., Greene E.C., Biggins S., Keeney S., Miller E.A., Fromme J.C., Hendrickson T.L., Cong Q., Baker D.
Science, 10 Dec 2021, 374(6573):eabm4805 DOI: 10.1126/science.abm4805
[34762488] - The coding and long noncoding single-ce ll atlas of the developing human fetal striatum.
Bocchi V.D., Conforti P., Vezzoli E., Besusso D., Cappadona C., Lischetti T., Galimberti M., Ranzani V., Bonnal R.J.P., Simone M.D., Rossetti G., He X., Kamimoto K., Espuny-Camacho I., Faedo A., Gervasoni F., Vuono R., Morris S.A., Chen J., Felsenfeld D., Pavesi G., Barker R.A.
Science, 01 May 2021, 372(6542):eabf5759 DOI: 10.1126/science.abf5759
[33958447] - Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells.
Marongiu L., Mingozzi F., Cigni C., Marzi R., Di Gioia M., Garrè M., Parazzoli D., Sironi L., Collini M., Sakaguchi R., Morii T., Crosti M., Moro M., Schurmans S., Catelani T., Rotem R., Colombo M., Shears S., Prosperi D., Zanoni I., Granucci F.
Science Signaling, 30 Mar 2021, 14(676):eaaz2120 DOI: 10.1126/scisignal.aaz2120
[PMC8091591] - LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response.
Faletti S., Osti D., Ceccacci E., Richichi C., Costanza B., Nicosia L., Noberini R., Marotta G., Furia L., Faretta M.R., Brambillasca S., Quarto M., Bertero L., Boldorini R., Pollo B., Gandini S., Cora D., Minucci S., Mercurio C., Varasi M., Bonaldi T., Pelicci G.
Science Translational Medicine, 08 Dec 2021, 13(623):eabf7036 DOI: 10.1126/scitranslmed.abf7036
[34878824] - Chromosomal-scale de novo genome assemblies of Cynomolgus Macaque and Common Marmoset.
Jayakumar V., Nishimura O., Kadota M., Hirose N., Sano H., Murakawa Y., Yamamoto Y., Nakaya M., Tsukiyama T., Seita Y., Nakamura S., Kawai J., Sasaki E., Ema M., Kuraku S., Kawaji H., Sakakibara Y.
Scientific Data, 28 Jun 2021, 8(1):159 DOI: 10.1038/s41597-021-00935-6
[s41597-021-00935-6] - Single cell imaging-based chromatin biomarkers for tumor progression.
Venkatachalapathy S., Jokhun D.S., Andhari M., Shivashankar G.V.
Scientific Reports, 29 Nov 2021, 11(1):23041 DOI: 10.1038/s41598-021-02441-6
[s41598-021-02441-6] - Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
Escala-Garcia M., Canisius S., Keeman R., Beesley J., Anton-Culver H., Arndt V., Augustinsson A., Becher H., Beckmann M.W., Behrens S., Bermisheva M., Bojesen S.E., Bolla M.K., Brenner H., Canzian F., Castelao J.E., Chang-Claude J., Chanock S.J., Couch F.J., Czene K., Daly M.B., Dennis J., Devilee P., Dörk T., Dunning A.M., Easton D.F., Ekici A.B., Eliassen A.H., Fasching P.A., Flyger H., Gago-Dominguez M., García-Closas M., García-Sáenz J.A., Geisler J., Giles G.G., Grip M., Gu?ndert M., Hahnen E., Haiman C.A., Håkansson N., Hall P., Hamann U., Hartikainen J.M., Heemskerk- Gerritsen B.A.M., Hollestelle A., Hoppe R., Hopper J.L., Hunter D.J., Jacot W., Jakubowska A., John E.M., Jung A.Y., Kaaks R., Khusnutdinova E., Koppert L.B., Kraft P., Kristensen V.N., Kurian A.W., Lambrechts D., Le Marchand L., Lindblom A., Luben R.N., Lubi?ski J., Mannermaa A., Manoochehri M., Margolin S., Mavroudis D., Muranen T.A., Nevanlinna H., Olshan A.F., Olsson H., Park-Simon T.-W., Patel A.V., Peterlongo P., Pharoah P.D.P., Punie K., Radice P., Rennert G., Rennert H.S., Romero A., Roylance R., Ru?diger T., Ruebner M., Saloustros E., Sawyer E.J., Schmutzler R.K., Schoemaker M.J., Scott C., Southey M.C., Surowy H., Swerdlow A.J., Tamimi R.M., Teras L.R., Thomas E., Tomlinson I., Troester M.A., Vachon C.M., Wang Q., Winqvist R., Wolk A., Ziogas A., Michailidou K., Chenevix-Trench G., Bachelot T., Schmidt M.K., kConFab/AOCS Investigators
Scientific Reports, 05 Oct 2021, 11(1):19787 DOI: 10.1038/s41598-021-99409-3
[s41598-021-99409-3] - Publisher Correction: Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology.
Cheroni C., Manganaro L., Donnici L., Bevilacqua V., Bonnal R.J.P., Rossi R.L., De Francesco R.
Scientific Reports, 30 Sep 2021, 11(1):19870 DOI: 10.1038/s41598-021-99452-0
[s41598-021-99452-0] - Strain maps characterize the symmetry of convergence and extension patterns during zebrafish gastrulation.
Bhattacharya D., Zhong J., Tavakoli S., Kabla A., Matsudaira P.
Scientific Reports, 29 Sep 2021, 11(1):19357 DOI: 10.1038/s41598-021-98233-z
[s41598-021-98233-z] - Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology.
Cheroni C., Manganaro L., Donnici L., Bevilacqua V., Bonnal R.J.P., Rossi R.L., De Francesco R.
Scientific Reports, 10 Sep 2021, 11(1):18043 DOI: 10.1038/s41598-021-97258-8
[s41598-021-97258-8] - Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing.
Nato G., Corti A., Parmigiani E., Jachetti E., Lecis D., Colombo M.P., Delia D., Buffo A., Magrassi L.
Scientific Reports, 12 Jan 2021, 11(1):651 DOI: 10.1038/s41598-020-79502-9
[s41598-020-79502-9] - MITO-Luc/GFP zebrafish model to assess spatial and temporal evolution of cell proliferation in vivo.
de Latouliere L., Manni I., Ferrari L., Pisati F., Totaro M.G., Gurtner A., Marra E., Pacello L., Pozzoli O., Aurisicchio L., Capogrossi M.C., Deflorian G., Piaggio G.
Scientific Reports, 12 Jan 2021, 11(1):671 DOI: 10.1038/s41598-020-79530-5
[s41598-020-79530-5] - Cap analysis of gene expression (CAGE) and noncoding regulatory elements.
Guerrini M.M., Oguchi A., Suzuki A., Murakawa Y.
Seminars in Immunopathology, 01 Sep 2021, 44(1):127-136 DOI: 10.1007/s00281-021-00886-5
[34468849] - Disentangling collective motion and local rearrangements in 2D and 3D ce ll assemblies.
Cerbino R., Villa S., Palamidessi A., Frittoli E., Scita G., Giavazzi F.
Soft Matter, 21 Dec 2020, 17(13):3550-3559 DOI: 10.1039/d0sm01837f
[33346771] - Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes.
Mangiameli E., Cecchele A., Morena F., Sanvito F., Matafora V., Cattaneo A., della Volpe L., Gnani D., Paulis M., Susani L., Martino S., Di Micco R., Bachi A., Gritti A.
Stem Cell Reports, 13 May 2021, 16(6):1478-1495 DOI: 10.1016/j.stemcr.2021.04.011
[33989519] - Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations: A Preclinical Study.
Oldenburg J., Malinverno M., Globisch M.A., Maderna C., Corada M., Orsenigo F., Conze L.L., Rorsman C., Sundell V., Arce M., Smith R.O., Yau A.C.Y., Billström G.H., Mägi C.Ö., Beznoussenko G.V., Mironov A.A., Fernando D., Daniel G., Olivari D., Fumagalli F., Lampugnani M.G., Dejana E., Magnusson P.U.
Stroke, 23 Feb 2021, 52(4):1418-1427 DOI: 10.1161/strokeaha.120.029676
[33618555] - Between mechanical clocks and emergent flocks: complexities in biology
Gross F.
December 2021Synthese 199(12) DOI:10.1007/s11229-021-03324-z
[s11229-021-03324-z] - Cellular and sub-cellular mechanisms of lipid transport from gut to lymph..
Sesorova I.S., Dimov I.D., Kashin A.D., Sesorov V.V., Karelina N.R., Zdorikova M.A., Beznoussenko G.V., Mir?n?v A.A.
Tissue & Cell, 20 Apr 2021, 72:101529 DOI: 10.1016/j.tice.2021.101529
[33915359] - The blood-brain and gut-vascular barriers: from the perspective of claudins.
Scalise A.A., Kakogiannos N., Zanardi F., Iannelli F., Giannotta M.
Tissue Barriers, 21 Jun 2021, 9(3):1926190 DOI: 10.1080/21688370.2021.1926190
[34152937] - DNA Damage Triggers a New Phase in Neurodegeneration.
Pessina F., Gioia U., Brandi O., Farina S., Ceccon M., Francia S., d’Adda di Fagagna F.
Trends in Genetics : TIG, 02 Oct 2020, 37(4):337-354 DOI: 10.1016/j.tig.2020.09.006
[33020022] - Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies.
Claesson-Welsh L., Dejana E., McDonald? D.M.
Trends in Molecular Medicine, 10 Dec 2020, 27(4):314-331 DOI: 10.1016/j.molmed.2020.11.006
[33309601]
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