IFOM Giorgio Scita Lab

Giorgio Scita Lab

Giorgio Scita

A cell biologist and expert on the dynamics of cell movement, Giorgio Scita directs the Mechanisms of Tumor Cell Migration research unit at IFOM.
Born in 1963 near Parma, Scita enrolled in the Faculty of Biology at the University of Parma in 1982 with a precise intention: to study animal behavior alongside the famous Italian ethologist Danilo Mainardi.
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Mechanisms of Tumor Cell Migration

The ability of multicellular tissue to alter their phenotypic and morphological characteristics, known as cellular plasticity, is critical in development, but also frequently exploited in adult life, such as during wound repair or de novo tissue vascularization, or in pathological situations, first and foremost during tumor dissemination.
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Laboratory location: Milan, Italy

Recent publications

  • Corallino S, Malabarba MG, Zobel M, Di Fiore PP, Scita G (2015)
    Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries.
    Frontiers in oncology 5: 45
  • Cremaschi P, Oliverio M, Leva V, Bione S, Carriero R, Mazzucco G, Palamidessi A, Scita G, Biamonti G, Montecucco A (2015)
    Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells.
    PLoS One 10: e0130561

Group members

Research assistant
Emanuela Frittoli
Andrea Palamidessi
Salvatore Corallino
Andrea Disanza
Hiroaki Kajiho
Gema Malet
Chiara Malinverno
PhD student
Sara Bisi
Abrar Rizvi
Undergraduate student
Davide Carra

IFOM Review

Breaking up is hard to do: role of an endocytic adaptor protein in epithelial cell cohesion and breast tumor metastasis
Commentary on Giorgio Scita's paper published in Developmental Cell, by Andrew Craig (2014)
On the fast track to invasion: intracellular trafficking drives tumor metastasis
Commentary on Giorgio Scita's paper published on Journal of Cell Biology, by Stefan Linder (2014)
YouScientist: a live research program for science conscious citizens
The first year of the new IFOM Science & Society program , by Giorgio Scita (2013)
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In the press

Tumori e Matematica

2015.04.12  | Enrico Orzes

Le cellule tumorali si muovono come stormi migratori
Corriere della Sera

2015.01.22 | Giovanni Caprara

Gli scienziati rispondono
Il Corriere della Sera

2013.09.27 | Giovanni Caprara

La proteina che paralizza le difese immunitarie


Le turbo du système immunitaire


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