IFOM Dana Branzei Lab

Dana Branzei Lab

Dana Branzei

Molecular biologist Dana Branzei is one of IFOM Milan's youngest tenured group leaders. Dana's laboratory researches mechanisms of DNA repair and replication stress tolerance that operate in eukaryotic cells, and the regulatory pathways that coordinate their usage. read more

Contact the researcher

DNA Repair

Accurate chromosomal DNA replication is of fundamental importance for cellular function, genome integrity and development. In response to replication perturbations, DNA damage response (DDR) and DNA damage tolerance (DDT) pathways become activated and are crucial for detection and tolerance of lesions, as well as for replication completion and chromosome structural integrity. read more

Laboratory location: Milan, Italy

Recent publications

  • Takuya Abe, Ryotaro Kawasumi, Hiroshi Arakawa, Tetsuya Hori, Katsuhiko Shirahige, Ana Losada, Tatsuo Fukagawa, and Dana Branzei* (2016).
    Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion.
    Oncotarget, doi: 10.18632/oncotarget.11982.
  • Dana Branzei* and Barnabas Szakal (2016).
    DNA damage tolerance by recombination: Molecular pathways and DNA structures.
    DNA Repair 44: 68-75.
  • Dana Branzei* and Ivan Psakhye (2016).
    DNA damage tolerance.
    Curr Opin Cell Biol 40: 137-144.
  • Demis Menolfi, Axel Delamarre, Armelle Lengronne, Philippe Pasero and Dana Branzei* (2015).
    Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.
    Mol Cell 60: 835-846. (see also comments on this article in PMID: 2668759, PMID:26694861)
  • Madhusoodanan Urulangodi, Marek Sebesta, Demis Menolfi, Barnabas Szakal, Julie Sollier, Alexandra Sisakova, Lumir Krejci, and Dana Branzei* (2015).
    Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.
    Genes Dev 29 (19). (see also comments on this article in PMID: 26587752).
  • Marco Fumasoni, Katharina Zwicky, Fabio Vanoli, Massimo Lopes and Dana Branzei* (2015).
    Error-free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polα/Primase/Ctf4 Complex.
    Mol Cell 57 (5): 812-823
    (see also comments on this article in Mol Cell Onc, DOI: 10.1080/23723556.2015.1035478).
  • * indicates the corresponding author

Group members

Staff Scientist
Barnabas Szakal
Postdoc fellows
Ivan Psakhye
Alexandra Mayer
Anja Waizzenegger
PhD students
Francesco Rossi
Ryotaro Kawasumi
Sumedha Agashe
Chinnu Rose Joseph
Research fellow
Valeria Dolce
Master Course university students
Teresa Anne Clarisse Reyes (University of Milan)
Former Lab members
Demis Menolfi (PhD student, postdoc)
Marco Fumasoni (PhD student, postdoc)
Federica Castellucci (PhD student, postdoc)
Saho Era (PhD student)
Takuya Abe (postdoc)
Madhusoodanan Urulangodi (postdoc)
Victor Gonzalez-Huici (postdoc)
Marek Sebesta (postdoc)
Fabio Vanoli (postdoc)
Julie Sollier (postdoc)
Eerappa Rajakumara (postdoc)
Livia Provitera (postdoc)

(update: september 2016)

IFOM Review

Seeing is believing: catching template-switching in the act
Commentary on Dana Branzei's paper published on Nature Structural & Molecular Biology, by Michael Lichten (2015)
complete review

Press releases


In the press

Quelli che decidono di restare in Italia
Il Corriere della Sera

2016.02.17 | G.Caprara, A. De Gregorio, V. Santarpia

Unravelling the secrets of DNA repair


DNA lifting
Marie Claire

2010.03.01 | Enrica Caretta

La poetessa del SUMO figlia del mondo


Ricera, italiani primi ma in fuga
Corriere della Sera

2009.10.08 | Gabriella Jacomella

view all press review