Angela Bachi Lab
Angela Bachi
Born in Genoa where she graduated in Pharmaceutical Chemistry & Technology in 1990 and in Pharmacy in 1991.
She got her PhD in analytical biochemistry at the Mario Negri Institute in Milan where she studied arachidonic acid metabolism and in vivo biosynthesis of prostacyclin and thromboxane to identify new metabolites indicators of free radical mediated lipid peroxidation in vivo.read more
Functional Proteomics
After the genomic revolution the focus of biological research is shifting from the description of singular interactions between macromolecular compounds, to the comprehensive qualitative and quantitative detection, measurement and mapping of complex molecular systems. To achieve this task we are developing and applying new technologies in the field of mass spectrometry-based proteomics and metabolomics.read more
Recent publications
- Jevtic Z, Matafora V, Casagrande F, Santoro F, Minucci S, Garre’ M, Rasouli M, Heidenreich O, Musco G, Schwaller J, Bachi A.
SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation.
J Exp Clin Cancer Res 2022 24;41(1):34. doi: 10.1186/s13046-022-02248-x. - Frayssinhes JA, Cerruti F, Laulin J, Cattaneo A, Bachi A, Apcher S, Coux O, Cascio P.
PA28γ-20S proteasome is a proteolytic complex committed to degrade unfolded proteins.
Mol Life Sci. 2021 Dec 16. doi: 10.1007/s00018-021-04045-9. - Cattaneo A, Martano G, Restuccia U, Tronci L, Bianchi M, Bachi A#, Matafora V.
Opti-nQL: An Optimized, Versatile and Sensitive Nano-LC Method for MS-Based Lipidomics Analysis.
Metabolites. 2021 Oct 21;11(11):720. doi: 10.3390/metabo11110720.