Advanced Light Microscopy
Serena Magni
Technician
Serena Magni holds a Master’s degree in Medical Biotechnology obtained in 2011. She joined IFOM in 2012 as a Flow Cytometry technician at the imaging facility, where she developed strong technical and theoretical skills in cytometry and began exploring microscopy and image analysis.
In 2019, she transitioned to the role of Bioimage Analyst within the Advanced Light Microscopy Facility. Here, she deepened her expertise in optical microscopy, particularly wide-field and confocal techniques, and expanded her skills in image analysis.
Serena is proficient in using software such as Fiji, CellProfiler, and Arivis, and has developed programming knowledge in Jython and Python to support quantitative image analysis workflows.
Publications Pre-IFOM
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miRNAs affect the expression of innate and adaptive immunity proteins in celiac disease.
Magni S, Buoli Comani G, Elli L, Vanessi S, Ballarini E, Nicolini G, Rusconi M, Castoldi M, Meneveri R, Muckenthaler MU, Bardella MT, Barisani D.
Am J Gastroenterol. 2014 Oct;109(10):1662-74. doi: 10.1038/ajg.2014.203. Epub 2014 Jul 29.PMID: 25070052
Publications IFOM
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GPR126 is a specifier of blood-brain barrier formation in the mouse central nervous system.
Kakogiannos N, Scalise AA, Martini E, Maderna C, Benvenuto AF, D'Antonio M, Carmignani L, Magni S, Gullotta GS, Lampugnani MG, Iannelli F, Beznoussenko GV, Mironov AA, Cerutti C, Bentley K, Philippides A, Zanardi F, Bacigaluppi M, Sigismund S, Bassani C, Farina C, Martino G, De Giovanni M, Dejana E, Iannacone M, Inverso D, Giannotta
M.J Clin Invest. 2024 Jun 6;134(15):e165368. doi: 10.1172/JCI165368.PMID: 39087467 Free PMC article. -
Clonal cooperation through soluble metabolite exchange facilitates metastatic outgrowth by modulating Allee effect.
Hershey BJ, Barozzi S, Orsenigo F, Pompei S, Iannelli F, Kamrad S, Matafora V, Pisati F, Calabrese L, Fragale G, Salvadori G, Martini E, Totaro MG, Magni S, Guan R, Parazzoli D, Maiuri P, Bachi A, Patil KR, Cosentino Lagomarsino M, Havas KM.
Sci Adv. 2023 Sep 15;9(37):eadh4184. doi: 10.1126/sciadv.adh4184. Epub 2023 Sep 15.PMID: 37713487 Free PMC article. -
Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M, Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C, Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita G.
Nat Mater. 2023 May;22(5):644-655. doi: 10.1038/s41563-022-01431-x. Epub 2022 Dec 29.PMID: 36581770 Free PMC article. -
Fasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects.
Cortellino S, Raveane A, Chiodoni C, Delfanti G, Pisati F, Spagnolo V, Visco E, Fragale G, Ferrante F, Magni S, Iannelli F, Zanardi F, Casorati G, Bertolini F, Dellabona P, Colombo MP, Tripodo C, Longo VD.
Cell Rep. 2022 Aug 23;40(8):111256. doi: 10.1016/j.celrep.2022.111256.PMID: 36001966 Free article. -
PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State.
Green BJ, Marazzini M, Hershey B, Fardin A, Li Q, Wang Z, Giangreco G, Pisati F, Marchesi S, Disanza A, Frittoli E, Martini E, Magni S, Beznoussenko GV, Vernieri C, Lobefaro R, Parazzoli D, Maiuri P, Havas K, Labib M, Sigismund S, Fiore PPD, Gunby RH, Kelley SO, Scita G.
Small. 2022 Apr;18(17):e2106097. doi: 10.1002/smll.202106097. Epub 2022 Mar 28.PMID: 35344274 Free article.
