Publications Marco Foiani

Martin Kosar, Michele Giannattasio, Daniele Piccini, Apolinar Maya-Mendoza, Francisco García-Benítez, Jirina Bartkova, Sonia I. Barroso, Hélène Gaillard, Umberto Restuccia, Massimiliano Garre, Eleonora Verga, Emanuele Martini, Miguel Andújar Sánchez, Scott Maynard, Zdenek Hodny, Amit Kumar, Angela Bachi, Andres Aguilera, Jiri Bartek, Marco Foiani.
Human nucleoporin Tpr coordinates mRNA processing to protect cells from RNA-mediated replication stress.
Nat Commun. 2021, in press.

Arta Ajazi, Christopher Bruhn, Ghadeer Shubassi, Chiara Lucca, Angela Cattaneo, Angela Bachi, Nicola Manfrini, Stefano Biffo, Emanuele Martini, Saverio Minucci, Claudio Vernieri, Marco Foiani.
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis.
Developmental Cell, 2021, in press.

Kidiyoor GR, Li Q, Bastianello G, Bruhn C, Giovannetti I, Mohamood A, Beznoussenko GV, Mironov A, Raab M, Piel M, Restuccia U, Matafora V, Bachi A, Barozzi S, Parazzoli D, Frittoli E, Palamidessi A, Panciera T, Piccolo S, Scita G, Maiuri P, Havas KM, Zhou ZW, Kumar A, Bartek J, Wang ZQ, Foiani M.
ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration,
Nat Commun. 2020 Sep 24;11(1):4828. doi: 10.1038/s41467-020-18580-9.PMID: 32973141.

Bruhn C, Ajazi A, Ferrari E, Lanz MC, Batrin R, Choudhary R, Walvekar A, Laxman S, Longhese MP, Fabre E, Smolka MB, Foiani M.
The Rad53 ^CHK1/CHK2-Spt21 ^NPAT and Tel1 ^ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing,
Nat Commun. 2020 Aug 19;11(1):4154. doi: 10.1038/s41467-020-17961-4., PMID: 32814778.

Achar YJ, Adhil M, Choudhary R, Gilbert N, Foiani M.
Negative supercoil at gene boundaries modulates gene topology.
Nature. 2020 Jan;577(7792):701-705. doi: 10.1038/s41586-020-1934-4. Epub 2020 Jan 22.

Bruhn C, Foiani M.
A model of DNA damage response activation at stalled replication forks by SPRTN.
Nat Commun. 2019 Dec 12;10(1):5671. doi: 10.1038/s41467-019-13610-7.

Achar YJ, Foiani M.
An Error-Prone Polymerase in the Fight against Cancer.
Cell. 2019 Mar 7;176(6):1241-1243. doi: 10.1016/j.cell.2019.02.011.

Kumar A, Mazzanti M, Mistrik M, Kosar M, Beznoussenko G, Mironov A, Garrè M, Parazzoli D, Shivashankar GV, Scita G, Bartek J and Foiani M. (2014)
ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.
Cell; 158(3): 633-46

Bermejo R., Capra T., Jossen R., Colosio A., Frattini C., Carotenuto W., Cocito A., Doksani Y., Klein H., Gómez-González B., Aguilera A., Katou Y., Shirahige K., Foiani M. (2011)
The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores.
Cell; 146 (2), 233-46

Robert T., Vanoli F., Chiolo I., Shubassi G., Bernstein K.A., Rothstein R., Botrugno O.A., Parazzoli D., Oldani A., Minucci S., Foiani M. (2011)
HDACs link the DNA damage response, processing of double-strand breaks and autophagy.
Nature; 471(7336), 74-9

Bermejo R., Capra T., Gonzalez-Huici V., Fachinetti D., Cocito A., Natoli G., Katou Y., Mori H., X Kurokawa, Shirahige K., Foiani M. (2009)
Genome-Organizing Factors Top2 and Hmo1 Prevent Chromosome Fragility at Sites of S phase Transcription.
Cell 138, p870.

Doksani Y., Bermejo R., Fiorani S., Haber J.E., Foiani M. (2009)
Replicon Dynamics, Dormant Origin Firing, and Terminal Fork Integrity after Double-Strand Break Formation.
Cell 137, 247-58

Branzei D., Vanoli F. and Foiani M. (2008)
SUMOylation regulates Rad18-mediated template switch.
Nature 456, 915-20.

Branzei D., Foiani M. (2007)
Template switching: from replication fork repair to genome rearrangements.
Cell, 131, 1228-30.

Branzei D., Sollier J., Liberi G., Zhao X., Maeda D., Seki M., Enomoto T., Ohta K., Foiani M. (2006)
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.
Cell, 127, 509-522.

Ira G., Pellicioli A., Balijja A., Wang X., Fiorani S., Carotenuto W., Liberi G., Bressan D., Wan L., Hollingsworth N.M., Haber J.E., Foiani M. (2004)
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1.
Nature,431, 1011-1017.

Liberi G., Foiani M. (2004)
Initiation of DNA replication: a new hint from archaea.
Cell, 116, 3-4.

Sogo J.M., Lopes M., Foiani M. (2002)
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects.
Science, 297, 599-602.

Lopes M., Cotta-Ramusino C., Pellicioli A., Liberi G., Plevani P., Muzi-Falconi M., Newlon C.S., Foiani M. (2001)
The DNA replication checkpoint response stabilizes stalled replication forks.
Nature, 412, 557-561.

(Last update:Oct 2021)