Positioning and reversible suppression of CCR7+ DCs in perivascular tumor niches shape cancer immunity.
Zitti B, Duval F, Wirapati P, Hicham M, Xie Y, Oh J, Hoelzl J, Meiser, Varrone M, Peterson HM, Cianciaruso C, Bill R, Bayerl F, Bolli E, Goubet AG, Kiss M, McDowell S, Cheng P, Celestini D, Terzic J, Zwahlen T, Alouche N, Zouggari N, Tarussio D, Tissot S, Nunes-Hasler P, Mino-Kenudson M, Lanuti M, Faquin WC, Sadow P, Tille JC, Labidi-Galy SI, Hugues S, Petrova TV, Ludewig B, Quezada S, Luther S, Tempel TR, Ciriello G, Pai SI, Michielin O, Böttcher JP, Weissleder R, Pittet MJ.
Manuscript under revision.
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers.
Bill R, Wirapati P, Messemaker M, Roh W, Zitti B, Duval F, Kiss M, Park JC, Saal TM, Hoelzl J, Tarussio D, Benedetti F, Tissot S, Varrone M, Ciriello G, McKee TA, Monnier Y, Mermod M, Blaum EM, Gushterova I, Gonye ALK, Hacohen N, Getz G, Mempel TR, Klein AM, Weissleder R, Faquin WC, Sadow P, Lin D, Pai SI, Sade-Feldman M, Pittet MJ.
Science. 2023;381(6657):515-524.
doi:10.1126/science.adg7846.
PMID: 37535729
Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a.
Zitti B, Hoffer H, Zheng W, Pandey RV, Schlums H, Perinetti Casoni G, Fusi I, Nguyen L, Kärner J, Kokkinou E, Carrasco A, Gahm J, Ehrström M, Happaniemi S, Keita AV, Hedin CRH, Mjösberg J, Eidsmo L, Bryceson YT.
Immunity. 2023;56(1):1-18.
doi:10.1016/j.immuni.2023.05.007.
PMID: 37269830
Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+ T cells.
Helm EY, Zelenka T, Cismasiu VB, Islam S, Silvane L, Zitti B, Holmes TD, Drashansky T, Kwiatkowski AJ, Tao C, Dean J, Obermayer AN, Chen X, Keselowsky BG, Zhang W, Huo Z, Zhou L, Sheridan B, Conejo-Garcia JR, Shaw TI, Bryceson YT, Avram D.
Sci Immunol. 2023;8(82):eabn0484.
doi:10.1126/sciimmunol.abn0484.
PMID: 37115913
A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional skin from patients with psoriasis.
Gallais Sérézal I, Hoffer E, Ignatov B, Martini E, Zitti B, Ehrström M, Eidsmo L.
J Allergy Clin Immunol. 2019;143(4):1444-1454.
doi:10.1016/j.jaci.2018.08.048.
PMID: 30268387