Deterministic actin waves as generators of cell polarization cues
Stankevicins L, Ecker N, Terriac E, Maiuri P, Schoppmeyer R, Vargas P, Lennon-Duménil AM, Piel M, Qu B, Hoth M, Kruse K, Lautenschläger F. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):826-835. doi: 10.1073/pnas.1907845117. Epub 2019 Dec 27. [31882452] IF 9,58
SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability
Rossi F, Helbling-Leclerc A, Kawasumi R, Jegadesan NK, Xu X, Devulder P, Abe T, Takata M, Xu D, Rosselli F, Branzei D. EMBO Rep. 2019 Dec 23:e48222. doi: 10.15252/embr.201948222. [Epub ahead of print] [31867888] IF 8,383
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families
Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J, Scarth J, Plaskocinska I, Luccarini C, Shah M, Pooley K, Dorling L, Lee A, Adank MA, Adlard J, Aittomäki K, Andrulis IL, Ang P, Barwell J, Bernstein JL, Bobolis K, Borg Â, Blomqvist C, Claes KBM, Concannon P, Cuggia A, Culver JO, Damiola F, de Pauw A, Diez O, Dolinsky JS, Domchek SM, Engel C, Evans DG, Fostira F, Garber J, Golmard L, Goode EL, Gruber SB, Hahnen E, Hake C, Heikkinen T, Hurley JE, Janavicius R, Kleibl Z, Kleiblova P, Konstantopoulou I, Kvist A, Laduca H, Lee ASG, Lesueur F, Maher ER, Mannermaa A, Manoukian S, McFarland R, McKinnon W, Meindl A, Metcalfe K, Mohd Taib NA, Moilanen J, Nathanson KL, Neuhausen S, Ng PS, Nguyen-Dumont T, Nielsen SM, Obermair F, Offit K, Olopade OI, Ottini L, Penkert J, Pylkäs K, Radice P, Ramus SJ, Rudaitis V, Side L, Silva-Smith R, Silvestri V, Skytte AB, Slavin T, Soukupova J, Tondini C, Trainer AH, Unzeitig G, Usha L, van Overeem Hansen T, Whitworth J, Wood M, Yip CH, Yoon SY, Yussuf A, Zogopoulos G, Goldgar D, Hopper JL, Chenevix-Trench G, Pharoah P, George SHL, Balmaña J, Houdayer C, et al. J Clin Oncol. 2019 Dec 16:JCO1901907. doi: 10.1200/JCO.19.01907. [Epub ahead of print] [31841383] IF 28,245
Squeezing in a Meal: Myosin Functions in Phagocytosis
Barger SR, Gauthier NC, Krendel M. Trends Cell Biol. 2019 Dec 10. pii: S0962-8924(19)30198-9. doi: 10.1016/j.tcb.2019.11.002. [Epub ahead of print] [31836280] IF 16,588
A subset of colorectal cancers with cross-sensitivity to olaparib and oxaliplatin
Arena S, Corti G, Durinikova E, Montone M, Reilly NM, Russo M, Lorenzato A, Arcella P, Lazzari L, Rospo G, Pagani M, Cancelliere C, Negrino C, Isella C, Bartolini A, Cassingena A, Amatu A, Mauri G, Sartore-Bianchi A, Mittica G, Medico E, Marsoni S, Linnebacher M, Abrignani S, Siena S, Di Nicolantonio F, Bardelli A. Clin Cancer Res. 2019 Dec 12. pii: clincanres.2409.2019. doi: 10.1158/1078-0432.CCR-19-2409. [Epub ahead of print] [31831554] IF 8,911
A model of DNA damage response activation at stalled replication forks by SPRTN
Bruhn C, Foiani M. Nat Commun. 2019 Dec 12;10(1):5671. doi: 10.1038/s41467-019-13610-7. [31831745] IF 11,878
Erratum: Nepravishta, R., et al. CoCUN, a Novel Ubiquitin Binding Domain Identified in N4BP1. Biomolecules 2019, 9, 284
Nepravishta R, Ferrentino F, Mandaliti W, Mattioni A, Weber J, Polo S, Castagnoli L, Cesareni G, Paci M, Santonico E. Biomolecules. 2019 Nov 28;9(12). pii: E803. doi: 10.3390/biom9120803. [31795258] IF 4,694
Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
Bhatt T, Bhosale A, Bajantri B, Mathapathi MS, Rizvi A, Scita G, Majumdar A, Jamora C. Cell Rep. 2019 Nov 26;29(9):2546-2555.e4. doi: 10.1016/j.celrep.2019.10.090. [31775025] IF 7,815
Global chromatin conformation differences in the Drosophila dosage compensated chromosome X
Pal K, Forcato M, Jost D, Sexton T, Vaillant C, Salviato E, Mazza EMC, Lugli E, Cavalli G, Ferrari F. Nat Commun. 2019 Nov 25;10(1):5355. doi: 10.1038/s41467-019-13350-8. [31767860] IF 11,878
CXCR3 Identifies Human Naive CD8(+) T Cells with Enhanced Effector Differentiation Potential
De Simone G, Mazza EMC, Cassotta A, Davydov AN, Kuka M, Zanon V, De Paoli F, Scamardella E, Metsger M, Roberto A, Pilipow K, Colombo FS, Tenedini E, Tagliafico E, Gattinoni L, Mavilio D, Peano C, Price DA, Singh SP, Farber JM, Serra V, Cucca F, Ferrari F, Orr√π V, Fiorillo E, Iannacone M, Chudakov DM, Sallusto F, Lugli E. J Immunol. 2019 Dec 15;203(12):3179-3189. doi: 10.4049/jimmunol.1901072. Epub 2019 Nov 18.
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome
Aguado J, Sola-Carvajal A, Cancila V, Revêchon G, Ong PF, Jones-Weinert CW, Wallén Arzt E, Lattanzi G, Dreesen O, Tripodo C, Rossiello F, Eriksson M, d'Adda di Fagagna F. Nat Commun. 2019 Nov 18;10(1):4990. doi: 10.1038/s41467-019-13018-3. [31740672] IF 11,878
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness
Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomäki K, Alducci E, Andrulis IL, Arason A, Arnold N, Artioli G, Arver B, Auber B, Azzollini J, Balmaña J, Barkardottir RB, Barnes DR, Barroso A, Barrowdale D, Belotti M, Benitez J, Bertelsen B, Blok MJ, Bodrogi I, Bonadona V, Bonanni B, Bondavalli D, Boonen SE, Borde J, Borg A, Bradbury AR, Brady A, Brewer C, Brunet J, Buecher B, Buys SS, Cabezas-Camarero S, Caldés T, Caliebe A, Caligo MA, Calvello M, Campbell IG, Carnevali I, Carrasco E, Chan TL, Chu ATW, Chung WK, Claes KBM, Collaborators GS, Collaborators E, Cook J, Cortesi L, Couch FJ, Daly MB, Damante G, Darder E, Davidson R, de la Hoya M, Della Puppa L, Dennis J, Díez O, Ding YC, Ditsch N, Domchek SM, Donaldson A, Dworniczak B, Easton DF, Eccles DM, Eeles RA, Ehrencrona H, Ejlertsen B, Engel C, Evans DG, Faivre L, Faust U, Feliubadaló L, Foretova L, Fostira F, Fountzilas G, Frost D, García-Barberá V, Garre P, Gauthier-Villars M, Géczi L, Gehrig A, Gerdes AM, Gesta P, Giannini G, Glendon G, Godwin AK, Goldgar DE, Greene MH, Gutierrez-Barrera AM, Hahnen E, Hamann U, et al. Cancer Res. 2019 Nov 13. pii: canres.1840.2019. doi: 10.1158/0008-5472.CAN-19-1840. [Epub ahead of print] [31723001] IF 8,378
Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness
Nigro EA, Distefano G, Chiaravalli M, Matafora V, Castelli M, Pesenti Gritti A, Bachi A, Boletta A. Sci Rep. 2019 Nov 12;9(1):16640. doi: 10.1038/s41598-019-53061-0. [31719603] IF 4,011
Correction: Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer
Bonetti P, Climent M, Panebianco F, Tordonato C, Santoro A, Marzi MJ, Pelicci PG, Ventura A, Nicassio F. Oncogene. 2019 Nov 8. doi: 10.1038/s41388-019-1094-x. doi: 10.1038/s41388-019-1094-x. [Epub ahead of print] [31705063] IF 6,634
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer
Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras SV, Pujol R, Kiiski JI, Muranen TA, Barnes DR, Dennis J, Michailidou K, Bolla MK, Leslie G, Aalfs CM; ABCTB Investigators, Adank MA, Adlard J, Agata S, Cadoo K, Agnarsson BA, Ahearn T, Aittomäki K, Ambrosone CB, Andrews L, Anton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Arun BK, Asseryanis E, Auber B, Auvinen P, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Barwell J, Beane Freeman LE, Beauparlant CJ, Beckmann MW, Behrens S, Benitez J, Berger R, Bermisheva M, Blanco AM, Blomqvist C, Bogdanova NV, Bojesen A, Bojesen SE, Bonanni B, Borg A, Brady AF, Brauch H, Brenner H, Brüning T, Burwinkel B, Buys SS, Caldés T, Caliebe A, Caligo MA, Campa D, Campbell IG, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Claes KBM, Clarke CL, Collavoli A, Conner TA, Cox DG, Cybulski C, Czene K, Daly MB, de la Hoya M, Devilee P, Diez O, Ding YC, Dite GS, Ditsch N, Domchek SM, Dorfling CM, Dos-Santos-Silva I, Durda K, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Foulkes WD, Friebel TM, Friedman E, Gabrielson M, Gaddam P, et al. NPJ Breast Cancer. 2019 Nov 1;5:38. doi: 10.1038/s41523-019-0127-5. eCollection 2019. [31700994] IF 6,23
Adaptive mutability of colorectal cancers in response to targeted therapies
Russo M, Crisafulli G, Sogari A, Reilly NM, Arena S, Lamba S, Bartolini A, Amodio V, Magrì A, Novara L, Sarotto I, Nagel ZD, Piett CG, Amatu A, Sartore-Bianchi A, Siena S, Bertotti A, Trusolino L, Corigliano M, Gherardi M, Lagomarsino MC, Di Nicolantonio F, Bardelli A. Science. 2019 Dec 20;366(6472):1473-1480. doi: 10.1126/science.aav4474. Epub 2019 Nov 7. [31699882] IF 41,063
HiCBricks: building blocks for efficient handling of large Hi-C datasets
Pal K, Tagliaferri I, Livi CM, Ferrari F. Bioinformatics. 2019 Nov 7. pii: btz808. doi: 10.1093/bioinformatics/btz808. [Epub ahead of print] [31697323] IF 4,531
Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension
Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension Nat Commun. 2019 Oct 31;10(1):4974. doi: 10.1038/s41467-019-12855-6. [31672988] IF 11,878
Correction to: A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit
Di Napoli A, Remotti D, Agostinelli C, Ambrosio MR, Ascani S, Carbone A, Facchetti F, Lazzi S, Leoncini L, Lucioni M, Novero D, Pileri S, Ponzoni M, Sabattini E, Tripodo C, Zamò A, Paulli M, Ruco L. Virchows Arch. 2019 Dec;475(6):799. doi: 10.1007/s00428-019-02696-5. [31664506] IF 2,868
SourceSet: A graphical model approach to identify primary genes in perturbed biological pathways
Salviato E, Djordjilovi? V, Chiogna M, Romualdi C. PloS Comput Biol. 2019 Oct 25;15(10):e1007357. doi: 10.1371/journal.pcbi.1007357. eCollection 2019 Oct. [31652275] IF 4,428
MicroRNA and Oxidative Stress Interplay in the Context of Breast Cancer Pathogenesis
Cosentino G, Plantamura I, Cataldo A, Iorio MV. Int J Mol Sci. 2019 Oct 17;20(20):5143. doi: 10.3390/ijms20205143. [31627322] IF 4,183
Impact of Metformin on Systemic Metabolism and Survival of Patients With Advanced Pancreatic Neuroendocrine Tumors
Vernieri C, Pusceddu S, de Braud F. Front Oncol. 2019 Sep 20;9:902. doi: 10.3389/fonc.2019.00902. eCollection 2019. [31616628] IF 4,137
Transient Photoinactivation of Cell Membrane Protein Activity without Genetic Modification by Molecular Hyperthermia
Kang P, Li X, Liu Y, Shiers SI, Xiong H, Giannotta M, Dejana E, Price TJ, Randrianalisoa J, Nielsen SO, Qin Z. ACS Nano. 2019 Nov 26;13(11):12487-12499. doi: 10.1021/acsnano.9b01993. Epub 2019 Oct 24. [31613606] IF 13,903
Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration
Hetmanski JHR, de Belly H, Busnelli I, Waring T, Nair RV, Sokleva V, Dobre O, Cameron A, Gauthier N, Lamaze C, Swift J, Del Campo A, Starborg T, Zech T, Goetz JG, Paluch EK, Schwartz JM, Caswell PT. Dev Cell. 2019 Nov 18;51(4):460-475.e10. doi: 10.1016/j.devcel.2019.09.006. Epub 2019 Oct 10. [31607653] IF 9,19
Development, technical validation, and clinical application of a multigene panel for hereditary gastrointestinal cancer and polyposis.
Ricci MT, Volorio S, Signoroni S, Mariani P, Mariette F, Sardella D, Pensotti V, Vitellaro M. Tumori. 2019 Aug;105(4):338-352. doi: 10.1177/0300891619847085. Epub 2019 May 8. [31068090] IF 1,234
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors
Pessina F, Giavazzi F, Yin Y, Gioia U, Vitelli V, Galbiati A, Barozzi S, Garre M, Oldani A, Flaus A, Cerbino R, Parazzoli D, Rothenberg E, d'Adda di Fagagna F. Nat Cell Biol. 2019 Oct;21(10):1286-1299. doi: 10.1038/s41556-019-0392-4. Epub 2019 Sep 30. [31570834] IF 17,728
Editorial: Accomplishments, Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition
Peterlongo P, Carvajal-Carmona LG. Front Oncol. 2019 Aug 28;9:841. doi: 10.3389/fonc.2019.00841. eCollection 2019. [31555594] IF 4,137
Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition
Abdel-Aziz AK, Pallavicini I, Ceccacci E, Meroni G, Saadeldin MK, Varasi M, Minucci S. Haematologica. 2019 Sep 19. pii: haematol.2019.224501. doi: 10.3324/haematol.2019.224501. [Epub ahead of print] [31537694] IF 7,57
Endothelial β-Catenin Signaling Supports Postnatal Brain and Retinal Angiogenesis by Promoting Sprouting, Tip Cell Formation, and VEGFR (Vascular Endothelial Growth Factor Receptor) 2 Expression
Martowicz A, Trusohamn M, Jensen N, Wisniewska-Kruk J, Corada M, Ning FC, Kele J, Dejana E, Nyqvist D. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2273-2288. doi: 10.1161/ATVBAHA.119.312749. Epub 2019 Sep 19. [31533473] IF 6,618
From injury to full repair: nerve regeneration and functional recovery in the common octopus, Octopus vulgaris
Imperadore P, Parazzoli D, Oldani A, Duebbert M, Büschges A, Fiorito G. J Exp Biol. 2019 Oct 9;222(Pt 19). pii: jeb209965. doi: 10.1242/jeb.209965. [31527179] IF 3,017
SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
Psakhye I, Castellucci F, Branzei D. Mol Cell. 2019 Nov 21;76(4):632-645.e6. doi: 10.1016/j.molcel.2019.08.003. Epub 2019 Sep 10. [31519521] IF 14,548
Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies studies and correlation with flt3 mutations and polyunsaturated fatty acid metabolism
Mazzarella L, Botteri E, Matthews A, Gatti E, Di Salvatore D, Bagnardi V, Breccia M, Montesinos P, Bernal T, Gil C, Ley TJ, Sanz M, Bhaskaran K, Lo Coco F, Pelicci PG. Haematologica. 2019 Sep 12. pii: haematol.2019.223925. doi: 10.3324/haematol.2019.223925. [Epub ahead of print] [31515354] IF 7,57
NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements
Hirabayashi S, Bhagat S, Matsuki Y, Takegami Y, Uehata T, Kanemaru A, Itoh M, Shirakawa K, Takaori-Kondo A, Takeuchi O, Carninci P, Katayama S, Hayashizaki Y, Kere J, Kawaji H, Murakawa Y. Nat Genet. 2019 Sep;51(9):1369-1379. doi: 10.1038/s41588-019-0485-9. Epub 2019 Sep 2. [31477927] IF 25,455
Two truncating variants in FANCC and breast cancer risk
Dörk T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Burwinkel B, Canzian F, Chan TL, Chang-Claude J, Chanock SJ, Choi JY, Christiansen H, Clarke CL, Couch FJ, Czene K, Daly MB, Dos-Santos-Silva I, Dwek M, Eccles DM, Ekici AB, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, Gao C, Gapstur SM, García-Closas M, García-S´enz JA, Gaudet MM, Giles GG, Goldberg MS, Goldgar DE, Guénel P, Haeberle L, Haiman CA, Håkansson N, Hall P, Hamann U, Hartman M, Hauke J, Hein A, Hillemanns P, Hogervorst FBL, Hooning MJ, Hopper JL, Howell T, Huo D, Ito H, Iwasaki M, Jakubowska A, Janni W, John EM, Jung A, Kaaks R, Kang D, Kapoor PM, Khusnutdinova E, Kim SW, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Kwong A, Lambrechts D, Marchand LL, Li J, Lindström S, Linet M, Lo WY, Long J, Lophatananon A, Lubi?ski J, Manoochehri M, Manoukian S, Margolin S, Martinez E, Matsuo K, Mavroudis D, Meindl A, et al. Sci Rep. 2019 Aug 29;9(1):12524. doi: 10.1038/s41598-019-48804-y. [31467304] IF 4,011
When Fasting Gets Tough, the Tough Immune Cells Get Going-or Die
Buono R, Longo VD. Cell. 2019 Aug 22;178(5):1038-1040. doi: 10.1016/j.cell.2019.07.052. [31442398] IF 36,216
Role of Intracellular Transport in the Centriole-Dependent Formation of Golgi Ribbon
Mironov AA, Dimov ID, Beznoussenko GV. Results Probl Cell Differ. 2019;67:49-79. doi: 10.1007/978-3-030-23173-6_4. [31435792] IF 3,022
Is cell migration a selectable trait in the natural evolution of cancer development?
Disanza A, Bisi S, Frittoli E, Malinverno C, Marchesi S, Palamidessi A, Rizvi A, Scita G. Philos Trans R Soc Lond B Biol Sci. 2019 Aug 19;374(1779):20180224. doi: 10.1098/rstb.2018.0224. Epub 2019 Jul 1. [31431177] IF 6,139
PP1 and PP2A Use Opposite Phospho-dependencies to Control Distinct Processes at the Kinetochore
Smith RJ, Cordeiro MH, Davey NE, Vallardi G, Ciliberto A, Gross F, Saurin AT. Cell Rep. 2019 Aug 20;28(8):2206-2219.e8. doi: 10.1016/j.celrep.2019.07.067. [31433993] IF 7,815
The Amount of Evidence Needed to Support ERBB2 as a Biomarker for Resistance to EGFR Inhibitors in Metastatic Colorectal Cancer
Sartore-Bianchi A, Marsoni S, Siena S. JAMA Oncol. 2019 Aug 15. doi: 10.1001/jamaoncol.2019.2982. doi: 10.1001/jamaoncol.2019.2982. [Epub ahead of print] [31415070] IF 22,4
A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit : A position paper from the Italian Group of Haematopathology (G.I.E.)
Di Napoli A, Remotti D, Agostinelli C, Ambrosio MR, Ascani S, Carbone A, Facchetti F, Lazzi S, Leoncini L, Lucioni M, Novero D, Pileri S, Ponzoni M, Sabattini E, Tripodo C, Zamò A, Paulli M, Ruco L. Virchows Arch. 2019 Oct;475(4):513-518. doi: 10.1007/s00428-019-02637-2. Epub 2019 Aug 6. [31388760] IF 2,868
Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment
Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, Colombo MP, Lamolinara A, Iezzi M, Ladomery M, Vernieri C, de Braud F, Di Nicola M, Tagliabue E, Castagnoli L, Pupa SM. Cell Oncol (Dordr). 2019 Dec;42(6):815-828. doi: 10.1007/s13402-019-00464-w. Epub 2019 Aug 2. [31376137] IF 5,02
How liquid biopsies can change clinical practice in oncology
Siravegna G, Mussolin B, Venesio T, Marsoni S, Seoane J, Dive C, Papadopoulos N, Kopetz S, Corcoran RB, Siu LL, Bardelli A. Ann Oncol. 2019 Oct 1;30(10):1580-1590. doi: 10.1093/annonc/mdz227. [31373349] IF 14,196
High Circulating Methylated DNA Is a Negative Predictive and Prognostic Marker in Metastatic Colorectal Cancer Patients Treated With Regorafenib
Amatu A, Schirripa M, Tosi F, Lonardi S, Bencardino K, Bonazzina E, Palmeri L, Patanè DA, Pizzutilo EG, Mussolin B, Bergamo F, Alberti G, Intini R, Procaccio L, Arese M, Marsoni S, Nichelatti M, Zagonel V, Siena S, Bardelli A, Loupakis F, Di Nicolantonio F, Sartore-Bianchi A, Barault L. Front Oncol. 2019 Jul 12;9:622. doi: 10.3389/fonc.2019.00622. eCollection 2019. [31355139] IF 4,137
The Role of Prep1 in the Regulation of Mesenchymal Stromal Cells
Maroni G, Panetta D, Luongo R, Krishnan I, La Rosa F, Campani D, Salvadori P, Iozzo P, Blasi F, Penkov D, Levantini E, Magli MC. Int J Mol Sci. 2019 Jul 25;20(15):3639. doi: 10.3390/ijms20153639. [31349607] IF 4,183
Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma
Palamidessi A, Malinverno C, Frittoli E, Corallino S, Barbieri E, Sigismund S, Beznoussenko GV, Martini E, Garre M, Ferrara I, Tripodo C, Ascione F, Cavalcanti-Adam EA, Li Q, Di Fiore PP, Parazzoli D, Giavazzi F, Cerbino R, Scita G. Nat Mater. 2019 Nov;18(11):1252-1263. doi: 10.1038/s41563-019-0425-1. Epub 2019 Jul 22. [31332337] IF 38,887
CoCUN, a Novel Ubiquitin Binding Domain Identified in N4BP1
Nepravishta R, Ferrentino F, Mandaliti W, Mattioni A, Weber J, Polo S, Castagnoli L, Cesareni G, Paci M, Santonico E. Biomolecules. 2019 Jul 17;9(7):284. doi: 10.3390/biom9070284. [31319543] IF 4,694
Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution
Wu Y, Li L, Frank L, Wagner J, Andreozzi P, Hammer B, D'Alicarnasso M, Pelliccia M, Liu W, Chakrabortty S, Krol S, Simon J, Landfester K, Kuan SL, Stellacci F, Müllen K, Kreppel F, Weil T. ACS Nano. 2019 Aug 27;13(8):8749-8759. doi: 10.1021/acsnano.9b01484. Epub 2019 Jul 29. [31322856] IF 13,903
Computational Biology Solutions to Identify Enhancers-target Gene Pairs
Hariprakash JM, Ferrari F. Comput Struct Biotechnol J. 2019 Jun 14;17:821-831. doi: 10.1016/j.csbj.2019.06.012. eCollection 2019. [31316726] IF 4,72
Mutant p53 improves cancer cells' resistance to endoplasmic reticulum stress by sustaining activation of the UPR regulator ATF6
Sicari D, Fantuz M, Bellazzo A, Valentino E, Apollonio M, Pontisso I, Di Cristino F, Dal Ferro M, Bicciato S, Del Sal G, Collavin L. Oncogene. 2019 Aug;38(34):6184-6195. doi: 10.1038/s41388-019-0878-3. Epub 2019 Jul 16. [31312025] IF 6,634
Plasma miRNA-based signatures in CRC screening programs
Zanutto S, Ciniselli CM, Belfiore A, Lecchi M, Masci E, Delconte G, Primignani M, Tosetti G, Dal Fante M, Fazzini L, Airoldi A, Vangeli M, Turpini F, Rubis Passoni GG, Viaggi P, Arena M, Motta RIO, Cant√π AM, Crosta C, De Roberto G, Iannuzzi F, Cassinotti A, Dall'Olio V, Tizzoni L, Sozzi G, Meroni E, Bisanti L, Pierotti MA, Verderio P, Gariboldi M. Int J Cancer. 2020 Feb 15;146(4):1164-1173. doi: 10.1002/ijc.32573. Epub 2019 Aug 5. [31304978] IF 4,982
YAP and TAZ: a signalling hub of the tumour microenvironment
Zanconato F, Cordenonsi M, Piccolo S. Nat Rev Cancer. 2019 Aug;19(8):454-464. doi: 10.1038/s41568-019-0168-y. [31270418] IF 51,848
Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression
Wagner W, Lippmann K, Heisler FF, Gromova KV, Lombino FL, Roesler MK, Pechmann Y, Hornig S, Schweizer M, Polo S, Schwarz JR, Eilers J, Kneussel M. Cell Rep. 2019 Jul 2;28(1):11-20.e9. doi: 10.1016/j.celrep.2019.06.005. [31269433] IF 7,815
Evolving neoantigen profiles in colorectal cancers with DNA repair defects
Rospo G, Lorenzato A, Amirouchene-Angelozzi N, Magrì A, Cancelliere C, Corti G, Negrino C, Amodio V, Montone M, Bartolini A, Barault L, Novara L, Isella C, Medico E, Bertotti A, Trusolino L, Germano G, Di Nicolantonio F, Bardelli A. Genome Med. 2019 Jun 28;11(1):42. doi: 10.1186/s13073-019-0654-6. [31253177] IF 10,886
Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions
Martano G, Borroni EM, Lopci E, Cattaneo MG, Mattioli M, Bachi A, Decimo I, Bifari F. Front Mol Neurosci. 2019 Jun 13;12:151. doi: 10.3389/fnmol.2019.00151. eCollection 2019. [31249511] IF 3,720
Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions
Fiume R, Faenza I, Sheth B, Poli A, Vidalle MC, Mazzetti C, Abdul SH, Campagnoli F, Fabbrini M, Kimber ST, Mariani GA, Xian J, Marvi MV, Mongiorgi S, Shah Z, Divecha N. Int J Mol Sci. 2019 Jun 19;20(12):2991. doi: 10.3390/ijms20122991. [31248120] IF 4,183
Endothelial cell clonal expansion in the development of cerebral cavernous malformations
Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, Pisati F, Fusco C, Graziano P, Giannotta M, Yu QC, Zeng YA, Lampugnani MG, Magnusson PU, Dejana E. Nat Commun. 2019 Jun 24;10(1):2761. doi: 10.1038/s41467-019-10707-x. [31235698] IF 11,878
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
Qian F, Rookus MA, Leslie G, Risch HA, Greene MH, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Andrulis IL, Arnold N, Arun BK, Ausems MGEM, Azzollini J, Barrowdale D, Barwell J, Benitez J, Bia?kowska K, Bonadona V, Borde J, Borg A, Bradbury AR, Brunet J, Buys SS, Caldés T, Caligo MA, Campbell I, Carter J, Chiquette J, Chung WK, Claes KBM, Collée JM, Collonge-Rame MA, Couch FJ, Daly MB, Delnatte C, Diez O, Domchek SM, Dorfling CM, Eason J, Easton DF, Eeles R, Engel C, Evans DG, Faivre L, Feliubadaló L, Foretova L, Friedman E, Frost D, Ganz PA, Garber J, Garcia-Barberan V, Gehrig A, Glendon G, Godwin AK, Gómez Garcia EB, Hamann U, Hauke J, Hopper JL, Hulick PJ, Imyanitov EN, Isaacs C, Izatt L, Jakubowska A, Janavicius R, John EM, Karlan BY, Kets CM, Laitman Y, L´zaro C, Leroux D, Lester J, Lesueur F, Loud JT, Lubi?ski J, ?ukomska A, McGuffog L, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Miller A, Montagna M, Mooij TM, Mouret-Fourme E, Nathanson KL, Nehoray B, Neuhausen SL, Nevanlinna H, Nielsen FC, Offit K, Olah E, Ong KR, Oosterwijk JC, Ottini L, Parsons MT, Peterlongo P, Pfeiler G, Pradhan N, et al. Br J Cancer. 2019 Jul;121(2):180-192. doi: 10.1038/s41416-019-0492-8. Epub 2019 Jun 19. [31213659] IF 5,416
The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries
Laitman Y, Friebel TM, Yannoukakos D, Fostira F, Konstantopoulou I, Figlioli G, Bonanni B, Manoukian S, Zuradelli M, Tondini C, Pasini B, Peterlongo P, Plaseska-Karanfilska D, Jakimovska M, Majidzadeh K, Zarinfam S, Loizidou MA, Hadjisavvas A, Michailidou K, Kyriacou K, Behar DM, Molho RB, Ganz P, James P, Parsons MT, Sallam A, Olopade OI, Seth A, Chenevix-Trench G, Leslie G, McGuffog L, Marafie MJ, Megarbane A, Al-Mulla F, Rebbeck TR, Friedman E. Hum Mutat. 2019 Nov;40(11):e1-e23. doi: 10.1002/humu.23842. Epub 2019 Jul 26. [31209999] IF 4,453
Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints
Alisafaei F, Jokhun DS, Shivashankar GV, Shenoy VB. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13200-13209. doi: 10.1073/pnas.1902035116. Epub 2019 Jun 17. [31209017] IF 9,58
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling
Pascolutti R, Algisi V, Conte A, Raimondi A, Pasham M, Upadhyayula S, Gaudin R, Maritzen T, Barbieri E, Caldieri G, Tordonato C, Confalonieri S, Freddi S, Malabarba MG, Maspero E, Polo S, Tacchetti C, Haucke V, Kirchhausen T, Di Fiore PP, Sigismund S. Cell Rep. 2019 Jun 4;27(10):3049-3061.e6. doi: 10.1016/j.celrep.2019.05.017. [31167147] IF 7,815
Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo
Menolfi D, Branzei D. Methods Mol Biol. 2019;2004:3-16. doi: 10.1007/978-1-4939-9520-2_1. [31147905] IF 10,71
In Vitro Detection of Long Noncoding RNA Generated from DNA Double-Strand Breaks
Sharma S, di Fagagna FD. Methods Mol Biol. 2019;2004:209-219. doi: 10.1007/978-1-4939-9520-2_16. [31147920] IF 10,71
Mechano-biological model of glioblastoma cells in response to osmotic stress
Pozzi G, Marchesi S, Scita G, Ambrosi D, Ciarletta P. Math Biosci Eng. 2019 Apr 1;16(4):2795-2810. doi: 10.3934/mbe.2019139. [31137238] IF 1,313
Editorial: From "Junk DNA" to Clinically Relevant Tools for Cancer Diagnosis, Staging, and Tailored Therapies: The Incredible Case of Non-Coding RNAs
Iorio MV, Palmieri D. Front Oncol. 2019 May 14;9:389. doi: 10.3389/fonc.2019.00389. eCollection 2019. [31139571] IF 4,137
Restriction of AID activity and somatic hypermutation by PARP-1
Tepper S, Mortusewicz O, Cz?onka E, Bello A, Schmidt A, Jeschke J, Fischbach A, Pfeil I, Petersen-Mahrt SK, Mangerich A, Helleday T, Leonhardt H, Jungnickel B. Nucleic Acids Res. 2019 Aug 22;47(14):7418-7429. doi: 10.1093/nar/gkz466. [31127309] IF 11,147
Resistance mechanisms to anti-HER2 therapies in HER2-positive breast cancer: Current knowledge, new research directions and therapeutic perspectives
Vernieri C, Milano M, Brambilla M, Mennitto A, Maggi C, Cona MS, Prisciandaro M, Fabbroni C, Celio L, Mariani G, Bianchi GV, Capri G, de Braud F. Crit Rev Oncol Hematol. 2019 Jul;139:53-66. doi: 10.1016/j.critrevonc.2019.05.001. Epub 2019 May 3. [31112882] IF 5,012
Cellular response upon proliferation in the presence of an active mitotic checkpoint
Corno A, Chiroli E, Gross F, Vernieri C, Matafora V, Maffini S, Cosentino Lagomarsino M, Bachi A, Ciliberto A. Life Sci Alliance. 2019 May 8;2(3):e201900380. doi: 10.26508/lsa.201900380. Print 2019 Jun. [31068378]
Collagen Prolyl Hydroxylation-Dependent Metabolic Perturbation Governs Epigenetic Remodeling and Mesenchymal Transition in Pluripotent and Cancer Cells
D'Aniello C, Cermola F, Palamidessi A, Wanderlingh LG, Gagliardi M, Migliaccio A, Varrone F, Casalino L, Matarazzo MR, De Cesare D, Scita G, Patriarca EJ, Minchiotti G. Cancer Res. 2019 Jul 1;79(13):3235-3250. doi: 10.1158/0008-5472.CAN-18-2070. Epub 2019 May 6. [31061065] IF 8,378
Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage
Poli A, Zaurito AE, Abdul-Hamid S, Fiume R, Faenza I, Divecha N. Int J Mol Sci. 2019 Apr 27;20(9):2080. doi: 10.3390/ijms20092080. [31035587] IF 4,183
Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3βMCL-1 Axis
Elgendy M, Cirò M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, Cazzoli R, Curigliano G, DeCensi A, Bonanni B, Budillon A, Pelicci PG, Janssens V, Ogris M, Baccarini M, Lanfrancone L, Weckwerth W, Foiani M, Minucci S. Cancer Cell. 2019 May 13;35(5):798-815.e5. doi: 10.1016/j.ccell.2019.03.007. Epub 2019 Apr 25. [31031016] IF 23,916
The Response to DNA Damage at Telomeric Repeats and Its Consequences for Telomere Function
Doksani Y. Genes (Basel). 2019 Apr 24;10(4):318. doi: 10.3390/genes10040318. [31022960]
Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs
Gioia U, Francia S, Cabrini M, Brambillasca S, Michelini F, Jones-Weinert CW, d'Adda di Fagagna F. Sci Rep. 2019 Apr 23;9(1):6460. doi: 10.1038/s41598-019-42892-6. [31015566] IF 4,011
Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis
Farina F, Ramkumar N, Brown L, Samandar Eweis D, Anstatt J, Waring T, Bithell J, Scita G, Thery M, Blanchoin L, Zech T, Baum B. EMBO J. 2019 Jun 3;38(11):e99843. doi: 10.15252/embj.201899843. Epub 2019 Apr 23. [31015335] IF 11,227
Network model of conviction-driven social segregation
Teza G, Suweis S, Gherardi M, Maritan A, Cosentino Lagomarsino M. Phys Rev E. 2019 Mar;99(3-1):032310. doi: 10.1103/PhysRevE?.99.032310. [30999432] IF 2,353
Correction to: DNA Damage In situ Ligation followed by Proximity Ligation Assay (DI-PLA)
Galbiati A, d'Adda di Fagagna F. Methods Mol Biol. 2019;1896:C3. doi: 10.1007/978-1-4939-8931-7_20. [30997669] IF 10,71
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Ferreira MA, Gamazon ER, Al-Ejeh F, Aittomäki K, Andrulis IL, Anton-Culver H, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Azzollini J, Balmaña J, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bia?kowska K, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Borg A, Brauch H, Brenner H, Broeks A, Burwinkel B, Caldés T, Caligo MA, Campa D, Campbell I, Canzian F, Carter J, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Christiansen H, Chung WK, Claes KBM, Clarke CL; EMBRACE Collaborators; GC-HBOC Study Collaborators; GEMO Study Collaborators, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, de la Hoya M, Dennis J, Devilee P, Diez O, Dörk T, Dunning AM, Dwek M, Eccles DM, Ejlertsen B, Ellberg C, Engel C, Eriksson M, Fasching PA, Fletcher O, Flyger H, Friedman E, Frost D, Gabrielson M, Gago-Dominguez M, Ganz PA, Gapstur SM, Garber J, García-Closas M, García-S´enz JA, Gaudet MM, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, Gonz´lez-Neira A, Greene MH, Gronwald J, Guénel P, Haiman CA, Hall P, Hamann U, He W, Heyworth J, Hogervorst FBL, Hollestelle A, Hoover RN, Hopper JL, Hulick PJ, Humphreys K, Imyanitov EN; ABCTB Investigators; HEBON Investigators; BCFR Investigators, et al. Nat Commun. 2019 Apr 15;10(1):1741. doi: 10.1038/s41467-018-08053-5. [30988301] IF 11,878
A Highly Luminescent Tetrahydrocurcumin Ir(III) Complex with Remarkable Photoactivated Anticancer Activity
Colombo A, Fontani M, Dragonetti C, Roberto D, Williams JAG, Scotto di Perrotolo R, Casagrande F, Barozzi S, Polo S. Chemistry. 2019 Jun 12;25(33):7948-7952. doi: 10.1002/chem.201901527. Epub 2019 May 13. [30985041] IF 5,16
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology
Corti G, Bartolini A, Crisafulli G, Novara L, Rospo G, Montone M, Negrino C, Mussolin B, Buscarino M, Isella C, Barault L, Siravegna G, Siena S, Marsoni S, Di Nicolantonio F, Medico E, Bardelli A. Clin Colorectal Cancer. 2019 Jun;18(2):91-101.e3. doi: 10.1016/j.clcc.2019.02.008. Epub 2019 Mar 7. [30981604] IF 3,176
RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci
Michelini F, Rossiello F, d'Adda di Fagagna F, Francia S. Nat Protoc. 2019 May;14(5):1489-1508. doi: 10.1038/s41596-019-0147-5. Epub 2019 Apr 8. [30962605] IF 11,334
Modulation of peripheral blood immune cells by early use of steroids and its association with clinical outcomes in patients with metastatic non-small cell lung cancer treated with immune checkpoint inhibitors
Fucà G, Galli G, Poggi M, Lo Russo G, Proto C, Imbimbo M, Ferrara R, Zilembo N, Ganzinelli M, Sica A, Torri V, Colombo MP, Vernieri C, Balsari A, de Braud F, Garassino MC, Signorelli D. ESMO Open. 2019 Feb 27;4(1):e000457. doi: 10.1136/esmoopen-2018-000457. eCollection 2019. [30964126]
HER2 Positivity Predicts Unresponsiveness to EGFR-Targeted Treatment in Metastatic Colorectal Cancer
Sartore-Bianchi A, Amatu A, Porcu L, Ghezzi S, Lonardi S, Leone F, Bergamo F, Fenocchio E, Martinelli E, Borelli B, Tosi F, Racca P, Valtorta E, Bonoldi E, Martino C, Vaghi C, Marrapese G, Ciardiello F, Zagonel V, Bardelli A, Trusolino L, Torri V, Marsoni S, Siena S. Oncologist. 2019 Oct;24(10):1395-1402. doi: 10.1634/theoncologist.2018-0785. Epub 2019 Apr 5. [30952821] IF 5,252
Detection of ubiquitinated targets in mammalian and Drosophila models
Maspero E, Fajner V, Weber J, Polo S. Methods Enzymol. 2019;619:293-318. doi: 10.1016/bs.mie.2018.12.030. Epub 2019 Feb 11. [30910026] IF 1,862
FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice
Marcuzzo S, Isaia D, Bonanno S, Malacarne C, Cavalcante P, Zacheo A, Laquintana V, Denora N, Sanavio B, Salvati E, Andreozzi P, Stellacci F, Krol S, Mellado-López M, Mantegazza R, Moreno-Manzano V, Bernasconi P. Cells. 2019 Mar 23;8(3):279. doi: 10.3390/cells8030279. [30909571] IF 5,656
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism
Bertolio R, Napoletano F, Mano M, Maurer-Stroh S, Fantuz M, Zannini A, Bicciato S, Sorrentino G, Del Sal G. Nat Commun. 2019 Mar 22;10(1):1326. doi: 10.1038/s41467-019-09152-7. [30902980] IF 11,878
Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis
Barger SR, Reilly NS, Shutova MS, Li Q, Maiuri P, Heddleston JM, Mooseker MS, Flavell RA, Svitkina T, Oakes PW, Krendel M, Gauthier NC. Nat Commun. 2019 Mar 19;10(1):1249. doi: 10.1038/s41467-019-09104-1. [30890704] IF 11,878
F-actin dynamics regulates mammalian organ growth and cell fate maintenance
Pocaterra A, Santinon G, Romani P, Brian I, Dimitracopoulos A, Ghisleni A, Carnicer-Lombarte A, Forcato M, Braghetta P, Montagner M, Galuppini F, Aragona M, Pennelli G, Bicciato S, Gauthier N, Franze K, Dupont S. J Hepatol. 2019 Jul;71(1):130-142. doi: 10.1016/j.jhep.2019.02.022. Epub 2019 Mar 14. [30878582] IF 18,946
Oncogenic Hijacking of the PIN1 Signaling Network
Zannini A, Rustighi A, Campaner E, Del Sal G. Front Oncol. 2019 Feb 25;9:94. doi: 10.3389/fonc.2019.00094. eCollection 2019. [30873382] IF 4,137
The B-cell receptor in control of tumor B-cell fitness: Biology and clinical relevance
Casola S, Perucho L, Tripodo C, Sindaco P, Ponzoni M, Facchetti F. Immunol Rev. 2019 Mar;288(1):198-213. doi: 10.1111/imr.12738. [30874349] IF 11,292
RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
Pezone A, Zuchegna C, Tramontano A, Romano A, Russo G, de Rosa M, Vinciguerra M, Porcellini A, Gottesman ME, Avvedimento EV. Sci Rep. 2019 Mar 8;9(1):3925. doi: 10.1038/s41598-019-40123-6. [30850627] IF 4,011
Identification and clinical validation of a multigene assay that interrogates the biology of cancer stem cells and predicts metastasis in breast cancer: A retrospective consecutive study
Pece S, Disalvatore D, Tosoni D, Vecchi M, Confalonieri S, Bertalot G, Viale G, Colleoni M, Veronesi P, Galimberti V, Di Fiore PP. EBioMedicine?. 2019 Apr;42:352-362. doi: 10.1016/j.ebiom.2019.02.036. Epub 2019 Mar 5. [30846393] IF 6,68
An Error-Prone Polymerase in the Fight against Cancer
Achar YJ, Foiani M. Cell. 2019 Mar 7;176(6):1241-1243. doi: 10.1016/j.cell.2019.02.011. [30849368] IF 36,216
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Rangan P, Choi I, Wei M, Navarrete G, Guen E, Brandhorst S, Enyati N, Pasia G, Maesincee D, Ocon V, Abdulridha M, Longo VD. Cell Rep. 2019 Mar 5;26(10):2704-2719.e6. doi: 10.1016/j.celrep.2019.02.019. [30840892] IF 7,815
Plasma HER2 (ERBB2) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer
Siravegna G, Sartore-Bianchi A, Nagy RJ, Raghav K, Odegaard JI, Lanman RB, Trusolino L, Marsoni S, Siena S, Bardelli A. Clin Cancer Res. 2019 May 15;25(10):3046-3053. doi: 10.1158/1078-0432.CCR-18-3389. Epub 2019 Feb 26. [30808777] IF 8,911
DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae
Giannattasio M, Branzei D. Genes (Basel). 2019 Feb 21;10(2):167. doi: 10.3390/genes10020167. [30795600] IF 3,331
Spindle pole power in health and disease
Raspelli E, Fraschini R. Curr Genet. 2019 Aug;65(4):851-855. doi: 10.1007/s00294-019-00941-7. Epub 2019 Feb 20. [30788566] IF 3,464
Genome-wide association study of germline variants and breast cancer-specific mortality
Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman R, Dennis J, Beesley J, Lecarpentier J, Bolla MK, Wang Q, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Boeckx B, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H, Brenner H, Brentnall A, Brinton L, Broberg P, Brock IW, Brucker SY, Burwinkel B, Caldas C, Caldés T, Campa D, Canzian F, Carracedo A, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Cheng TD, Chin SF, Clarke CL; NBCS Collaborators, Cordina-Duverger E, Couch FJ, Cox DG, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dunn JA, Dunning AM, Durcan L, Dwek M, Earl HM, Ekici AB, Eliassen AH, Ellberg C, Engel C, Eriksson M, Evans DG, Figueroa J, Flesch-Janys D, Flyger H, Gabrielson M, Gago-Dominguez M, Galle E, Gapstur SM, García-Closas M, García-S´enz JA, Gaudet MM, George A, Georgoulias V, Giles GG, Glendon G, Goldgar DE, Gonz´lez-Neira A, Alnæs GIG, Grip M, Guénel P, Haeberle L, Hahnen E, Haiman CA, Håkansson N, Hall P, Hamann U, Hankinson S, Harkness EF, Harrington PA, Hart SN, Hartikainen JM, Hein A, Hillemanns P, Hiller L, Holleczek B, et al. Br J Cancer. 2019 Mar;120(6):647-657. doi: 10.1038/s41416-019-0393-x. Epub 2019 Feb 21. [30787463] IF 5,416
Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells
Travelli C, Consonni FM, Sangaletti S, Storto M, Morlacchi S, Grolla AA, Galli U, Tron GC, Portararo P, Rimassa L, Pressiani T, Mazzone M, Trovato R, Ugel S, Bronte V, Tripodo C, Colombo MP, Genazzani AA, Sica A. Cancer Res. 2019 Apr 15;79(8):1938-1951. doi: 10.1158/0008-5472.CAN-18-1544. Epub 2019 Feb 18. [30777853] IF 8,378
Combination of Baseline LDH, Performance Status and Age as Integrated Algorithm to Identify Solid Tumor Patients with Higher Probability of Response to Anti PD-1 and PD-L1 Monoclonal Antibodies
Cona MS, Lecchi M, Cresta S, Damian S, Del Vecchio M, Necchi A, Poggi MM, Raggi D, Randon G, Ratta R, Signorelli D, Vernieri C, de Braud F, Verderio P, Di Nicola M. Cancers (Basel). 2019 Feb 14;11(2):223. doi: 10.3390/cancers11020223. [30769874] IF 6,162
Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates
Gallo D, Kim T, Szakal B, Saayman X, Narula A, Park Y, Branzei D, Zhang Z, Brown GW. Mol Cell. 2019 Mar 7;73(5):900-914.e9. doi: 10.1016/j.molcel.2019.01.001. Epub 2019 Feb 4. [30733119] IF 14,548
Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model
Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A. Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x. [30728389] IF 4,011
Data on the inhibition of cell proliferation and invasion by the D2A-Ala peptide derived from the urokinase receptor
Furlan F, Eden G, Archinti M, Arnaudova R, Andreotti G, Citro V, Cubellis MV, Motta A, Degryse B. Data Brief. 2019 Jan 9;22:903-908. doi: 10.1016/j.dib.2019.01.009. eCollection 2019 Feb. [30723759] IF 0,97
A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T. Sci Rep. 2019 Feb 4;9(1):1211. doi: 10.1038/s41598-018-37780-4. [30718891] IF 4,011
Redundant and nonredundant organismal functions of EPS15 and EPS15L1
Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko GV, Raimondi A, Soppo BE, Amodio S, Caldieri G, Malabarba MG, Bertalot G, Confalonieri S, Parazzoli D, Mironov AA, Tacchetti C, Di Fiore PP, Sigismund S, Offenhäuser N. Life Sci Alliance. 2019 Jan 28;2(1):e201800273. doi: 10.26508/lsa.201800273. Print 2019 Feb. [30692166]
DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients
Corti A, Sota R, Dugo M, Calogero RA, Terragni B, Mantegazza M, Franceschetti S, Restelli M, Gasparini P, Lecis D, Chrzanowska KH, Delia D. Sci Rep. 2019 Jan 24;9(1):651. doi: 10.1038/s41598-018-36912-0. [30679601] IF 6,537
Selectivity of the CUBAN domain in the recognition of ubiquitin and NEDD8
Castagnoli L, Mandaliti W, Nepravishta R, Valentini E, Mattioni A, Procopio R, Iannuccelli M, Polo S, Paci M, Cesareni G, Santonico E. FEBS J. 2019 Feb;286(4):653-677. doi: 10.1111/febs.14752. Epub 2019 Feb 5. [30659753] IF 4,739
Reply to 'Fasting in oncology: a word of caution'
Nencioni A, Caffa I, Cortellino S, Longo VD. Nat Rev Cancer. 2019 Mar;19(3):178. doi: 10.1038/s41568-018-0100-x. [30651605] IF 51,848
Single-Agent Gemcitabine vs. Carboplatin-Gemcitabine in Advanced Breast Cancer: A Retrospective Comparison of Efficacy and Safety Profiles
Vernieri C, Prisciandaro M, Milano M, Cona MS, Maggi C, Brambilla M, Mennitto A, Fabbroni C, Farè E, Cresta S, Celio L, Mariani G, Bianchi G, Capri G, de Braud F. Clin Breast Cancer. 2019 Apr;19(2):e306-e318. doi: 10.1016/j.clbc.2018.12.004. Epub 2018 Dec 12. [30635175] IF 2,762
NIPBL: a new player in myeloid cell differentiation
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A. Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10. [30630974] IF 7,57
Increased soluble urokinase plasminogen activator receptor (suPAR) levels in neovascular age-related macular degeneration: a role for inflammation in the pathogenesis of the disease?
Scotti F, Milani P, Setaccioli M, Maestroni S, Sidenius N, De Lorenzi V, Massacesi A, Bergamini F, Zerbini G. Graefes Arch Clin Exp Ophthalmol. 2019 May;257(5):899-903. doi: 10.1007/s00417-018-04230-w. Epub 2019 Jan 7. [30617582] IF 2,25
Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial
Vernieri C, Signorelli D, Galli G, Ganzinelli M, Moro M, Fabbri A, Tamborini E, Marabese M, Caiola E, Broggini M, Hollander L, Gallucci R, Vandoni G, Gavazzi C, Triulzi T, Colombo MP, Rizzo AM, Corsetto PA, Pruneri G, de Braud F, Sozzi G, Torri V, Garassino MC. Clin Lung Cancer. 2019 May;20(3):e413-e417. doi: 10.1016/j.cllc.2018.12.011. Epub 2018 Dec 19. [30617039] IF 4,117
Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy
Rizzolo P, Zelli V, Silvestri V, Valentini V, Zanna I, Bianchi S, Masala G, Spinelli AM, Tibiletti MG, Russo A, Varesco L, Giannini G, Capalbo C, Calistri D, Cortesi L, Viel A, Bonanni B, Azzollini J, Manoukian S, Montagna M, Peterlongo P, Radice P, Palli D, Ottini L. Int J Cancer. 2019 Jul 15;145(2):390-400. doi: 10.1002/ijc.32106. Epub 2019 Jan 24. [30613976] IF 4,982
Retreatment with anti-EGFR monoclonal antibodies in metastatic colorectal cancer: Systematic review of different strategies
Mauri G, Pizzutilo EG, Amatu A, Bencardino K, Palmeri L, Bonazzina EF, Tosi F, Carlo Stella G, Burrafato G, Scaglione F, Marsoni S, Siravegna G, Bardelli A, Siena S, Sartore-Bianchi A. Cancer Treat Rev. 2019 Feb;73:41-53. doi: 10.1016/j.ctrv.2018.12.006. Epub 2018 Dec 27. [30616224] IF 8,332
Prep1 (pKnox1) transcription factor contributes to pubertal mammary gland branching morphogenesis
Sicouri L, Pisati F, Pece S, Blasi F, Longobardi E. Int J Dev Biol. 2018;62(11-12):827-836. doi: 10.1387/ijdb.180278fb. [30604852] IF 1,092
The genetics and the molecular functions of the PREP1 homeodomain transcription factor
Purushothaman D, Blasi F. Int J Dev Biol. 2018;62(11-12):819-825. doi: 10.1387/ijdb.180238fb. [30604851] IF 1,092
Performance of tumor testing for Lynch syndrome identification in patients with colorectal cancer: A retrospective single-center study.
Signoroni S, Tibiletti MG, Ricci MT, Milione M, Perrone F, Pensotti V, Chiaravalli AM, Carnevali I, Morabito A, Bertario L, Vitellaro M. Tumori. 2019 Feb;105(1):76-83. doi: 10.1177/0300891618792460. Epub 2018 Aug 17. [30117378] IF 1,234