IFOM Pubblicazioni 2014
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Pubblicazioni 2014

In ordine cronologico - ultimo aggiornamento Maggio 2015
  1. Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner.
    Elgendy M, Ciro M, Abdel-Aziz AK, Belmonte G, Dal Zuffo R, Mercurio C, Miracco C, Lanfrancone L, Foiani M, Minucci S.
    Nat Commun. 2014 Dec 4;5:5637. doi: 10.1038/ncomms6637.
    [PMID: 25472497] IF 10,7420

  2. SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity.
    Marino M, Stoilova T, Giorgi C, Bachi A, Cattaneo A, Auricchio A, Pinton P, Zito E.
    Hum Mol Genet. 2014 Dec 1. doi:pii: ddu602. [Epub ahead of print]
    [PMID: 25452428] IF 6,6770

  3. Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.
    Bonanomi M, Natalello A, Visentin C, Pastori V, Penco A, Cornelli G, Colombo G, Malabarba MG, Doglia SM, Relini A, Regonesi ME, Tortora P.
    Hum Mol Genet. 2014 Dec 15;23(24):6542-52. doi: 10.1093/hmg/ddu373. Epub 2014 Jul 16.
    [PMID: 25030034] IF 6,6770

  4. RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.
    Manfrini N, Trovesi C, Wery M, Martina M, Cesena D, Descrimes M, Morillon A, d'Adda di Fagagna F, Longhese MP.
    EMBO Rep. 2014 Dec 19. doi:pii: e201439458. [Epub ahead of print]
    [PMID: 25527408]IF 7,8580

  5. Genetic transformation of structural and functional circuitry rewires the Drosophila brain.
    Sen S, Cao D, Choudhary R, Biagini S, Wang JW, Reichert H, VijayRaghavan K.
    Elife. 2014 Dec 29;3. doi: 10.7554/eLife.04407. [Epub ahead of print]
    [PMID: 25546307] IF 8,5190

  6. TGFα and Amphiregulin Paracrine Network Promotes Resistance to EGFR Blockade in Colorectal Cancer Cells.
    Hobor S, Van Emburgh BO, Crowley E, Misale S, Di Nicolantonio F, Bardelli A.
    Clin Cancer Res. 2014 Dec 15;20(24):6429-38. doi: 10.1158/1078-0432.CCR-14-0774. Epub 2014 Jun 10.
    [PMID: 24916700] IF 8,1930

  7. Circulating pEGFR Is a Candidate Response Biomarker of Cetuximab Therapy in Colorectal Cancer.
    Katsila T, Juliachs M, Gregori J, Macarulla T, Villarreal L, Bardelli A, Torrance C, Elez E, Tabernero J, Villanueva J.
    Clin Cancer Res. 2014 Dec 15;20(24):6346-56. doi: 10.1158/1078-0432.CCR-14-0361. Epub 2014 Oct 16.
    [PMID: 25324142] IF 8,1930

  8. The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations.
    Bodini M, Ronchini C, Giacò L, Russo A, Melloni GE, Luzi L, Sardella D, Volorio S, Hasan SK, Ottone T, Lavorgna S, Lo-Coco F, Candoni A, Fanin R, Toffoletti E, Iacobucci I, Martinelli G, Cignetti A, Tarella C, Bernard L, Pelicci PG, Riva L.
    Blood. 2014 Dec 12. doi:pii: blood-2014-05-576157. [Epub ahead of print]
    [PMID: 25499761] IF 9,7750

  9. 3D Traction Stresses Activate Protease-Dependent Invasion of Cancer Cells.
    Aung A, Seo YN, Lu S, Wang Y, Jamora C, Del Álamo JC, Varghese S.
    Biophys J. 2014 Dec 2;107(11):2528-37. doi: 10.1016/j.bpj.2014.07.078. Epub 2014 Dec 2.
    [PMID: 25468332] IF 3,8320

  10. Protein and amino acid restriction, aging and disease: from yeast to humans.
    Mirzaei H, Suarez JA, Longo VD.
    Trends Endocrinol Metab. 2014 Nov;25(11):558-566. doi: 10.1016/j.tem.2014.07.002. Epub 2014 Aug 19.
    [PMID: 25153840] IF 8,8680

  11. Structural and functional framework for the autoinhibition of nedd4-family ubiquitin ligases.
    Mari S, Ruetalo N, Maspero E, Stoffregen MC, Pasqualato S, Polo S, Wiesner S.
    Structure. 2014 Nov 4;22(11):1639-49. doi: 10.1016/j.str.2014.09.006. Epub 2014 Oct 30.
    [PMID: 25438670] IF 6,7940

  12. MicroRNA related polymorphisms and breast cancer risk.
    Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, et al.
    PLoS One. 2014;9(11):e109973. doi: 10.1371/journal.pone.0109973.
    [PMID: 25390939] IF 3,5340

  13. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.
    Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, et al.
    Hum Mol Genet. 2014 Nov 15;23(22):6034-46. doi: 10.1093/hmg/ddu300. Epub 2014 Jun 13.
    [PMID: 24927736] IF 6,6770

  14. Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution.
    Misale S, Di Nicolantonio F, Sartore-Bianchi A, Siena S, Bardelli A.
    Cancer Discov. 2014 Nov;4(11):1269-80. doi: 10.1158/2159-8290.CD-14-0462. Epub 2014 Oct 7.
    [PMID: 25293556] IF 15,9290

  15. Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.
    Milne RL, Burwinkel B, Michailidou K, Arias-Perez JI, Zamora MP, Menéndez-Rodríguez P, Hardisson D, Mendiola M, González-Neira A, Pita G, Alonso MR, Dennis J, Wang Q, Bolla MK, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Ko YD, Brauch H, Hamann U; GENICA Network, et al.
    Hum Mol Genet. 2014 Nov 15;23(22):6096-111. doi: 10.1093/hmg/ddu311. Epub 2014 Jun 18.
    [PMID: 24943594] IF 6,6770

  16. The interaction between uPAR and vitronectin triggers ligand-independent adhesion signalling by integrins.
    Ferraris GM, Schulte C, Buttiglione V, De Lorenzi V, Piontini A, Galluzzi M, Podestà A, Madsen CD, Sidenius N.
    EMBO J. 2014 Nov 3;33(21):2458-72. doi: 10.15252/embj.201387611. Epub 2014 Aug 28.
    [PMID: 25168639] IF 10,7480

  17. DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis.
    Marchesi S, Montani F, Deflorian G, D'Antuono R, Cuomo A, Bologna S, Mazzoccoli C, Bonaldi T, Di Fiore PP, Nicassio F.
    Dev Cell. 2014 Nov 24;31(4):420-33. doi: 10.1016/j.devcel.2014.09.009. Epub 2014 Nov 24.
    [PMID: 25458010] IF 10,3660

  18. Signaling pathways in the specification of arteries and veins.
    Corada M, Morini MF, Dejana E.
    Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2372-7. doi: 10.1161/ATVBAHA.114.303218. Epub 2014 Aug 28.
    [PMID: 25169934] IF 5,5330

  19. The genomic and epigenomic landscapes of AML.
    Mazzarella L, Riva L, Luzi L, Ronchini C, Pelicci PG.
    Semin Hematol. 2014 Oct;51(4):259-72. doi: 10.1053/j.seminhematol.2014.08.007. Epub 2014 Aug 26.
    [PMID: 25311739] IF 2,4620

  20. Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.
    Persaud A, Alberts P, Mari S, Tong J, Murchie R, Maspero E, Safi F, Moran MF, Polo S, Rotin D.
    Sci Signal. 2014 Oct 7;7(346):ra95. doi: 10.1126/scisignal.2005290.
    [PMID: 25292214] IF 6,3370

  21. Stable cellular senescence is associated with persistent DDR activation.
    Fumagalli M, Rossiello F, Mondello C, d'Adda di Fagagna F.
    PLoS One. 2014;9(10):e110969. doi: 10.1371/journal.pone.0110969.
    [PMID: 25340529] IF 3,5340

  22. H2B mono-ubiquitylation facilitates fork stalling and recovery during replication stress by coordinating Rad53 activation and chromatin assembly.
    Lin CY, Wu MY, Gay S, Marjavaara L, Lai MS, Hsiao WC, Hung SH, Tseng HY, Wright DE, Wang CY, Hsu GS, Devys D, Chabes A, Kao CF.
    PLoS Genet. 2014 Oct;10(10):e1004667. doi: 10.1371/journal.pgen.1004667.
    [PMID: 25275495] IF 8,1670

  23. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
    Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, et al.
    Nature. 2014 Oct 2;514(7520):92-7. doi: 10.1038/nature13545. Epub 2014 Jul 23.
    [PMID: 25231870] IF 42,3510

  24. Visualization of recombination-mediated damage bypass by template switching.
    Giannattasio M, Zwicky K, Follonier C, Foiani M, Lopes M, Branzei D.
    Nat Struct Mol Biol. 2014 Oct;21(10):884-92. doi: 10.1038/nsmb.2888. Epub 2014 Sep 7.
    [PMID: 25195051] IF 11,6330

  25. Mining cancer gene expression databases for latent information on intronic microRNAs.
    Monterisi S, D'Ario G, Dama E, Rotmensz N, Confalonieri S, Tordonato C, Troglio F, Bertalot G, Maisonneuve P, Viale G, Nicassio F, Vecchi M, Di Fiore PP, Bianchi F.
    Mol Oncol. 2014 Oct 15. doi:pii: S1574-7891(14)00237-3. 10.1016/j.molonc.2014.10.001. [Epub ahead of print]
    [PMID: 25459350] IF 5,9350

  26. From a 2DE-gel spot to protein function: lesson learned from HS1 in chronic lymphocytic leukemia.
    Apollonio B, Bertilaccio MT, Restuccia U, Ranghetti P, Barbaglio F, Ghia P, Caligaris-Cappio F, Scielzo C.
    J Vis Exp. 2014 Oct 19;(92):e51942. doi: 10.3791/51942.
    [PMID: 25350848]

  27. The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes.
    Crespo CL, Vernieri C, Keller PJ, Garré M, Bender JR, Wittbrodt J, Pardi R.
    J Cell Sci. 2014 Oct 15;127(Pt 20):4381-95. doi: 10.1242/jcs.146217. Epub 2014 Sep 1.
    [PMID: 25179599] IF 5,3250

  28. Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
    Alamo P, Gallardo A, Di Nicolantonio F, Pavón MA, Casanova I, Trias M, Mangues MA, Lopez-Pousa A, Villaverde A, Vázquez E, Bardelli A, Céspedes MV, Mangues R.
    FASEB J. 2014 Oct 30. doi:pii: fj.14-262303. [Epub ahead of print]
    [PMID: 25359494] IF 5,4800

  29. High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.
    Abe T, Branzei D.
    DNA Repair (Amst). 2014 Oct;22:153-64. doi: 10.1016/j.dnarep.2014.08.003. Epub 2014 Sep 16.
    [PMID: 25218467] IF 3,3620

  30. ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.
    Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, Butcher S, Manak JR, Vaccari T, Weinstein H, Anderson KV, Lacy E, Selleri L.
    Cell Rep. 2014 Oct 23;9(2):674-87. doi: 10.1016/j.celrep.2014.09.019. Epub 2014 Oct 16.
    [PMID: 25373905] IF 7,2070

  31. Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
    Risolino M, Mandia N, Iavarone F, Dardaei L, Longobardi E, Fernandez S, Talotta F, Bianchi F, Pisati F, Spaggiari L, Harter PN, Mittelbronn M, Schulte D, Incoronato M, Di Fiore PP, Blasi F, Verde P.
    Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3775-84. doi: 10.1073/pnas.1407074111. Epub 2014 Aug 25.
    [PMID: 25157139] IF 9,8090

  32. Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway.
    Modica L, Iotti G, D'Avola A, Blasi F.
    PLoS One. 2014;9(9):e107916. doi: 10.1371/journal.pone.0107916.
    [PMID: 25233378] IF 3,5340

  33. Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).
    Knappskog S, Gansmo LB, Dibirova K, Metspalu A, Cybulski C, Peterlongo P, Aaltonen L, Vatten L, Romundstad P, Hveem K, Devilee P, Evans GD, Lin D, Van Camp G, Manolopoulos VG, Osorio A, Milani L, Ozcelik T, Zalloua P, Mouzaya F, Bliznetz E, Balanovska E, et al.
    Oncotarget. 2014 Sep 30;5(18):8223-34.
    [PMID: 25327560] IF 6,6270

  34. The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.
    Molenaar RJ, Verbaan D, Lamba S, Zanon C, Jeuken JW, Boots-Sprenger SH, Wesseling P, Hulsebos TJ, Troost D, van Tilborg AA, Leenstra S, Vandertop WP, Bardelli A, van Noorden CJ, Bleeker FE.
    Neuro Oncol. 2014 Sep;16(9):1263-73. doi: 10.1093/neuonc/nou005. Epub 2014 Feb 6.
    [PMID: 24510240] IF 5,2860

  35. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis.
    Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H.
    Nat Commun. 2014 Sep 11;5:4839. doi: 10.1038/ncomms5839.
    [PMID: 25208761] IF 10,7420

  36. Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.
    Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, et al.
    Nat Commun. 2014 Sep 23;4:4999. doi: 10.1038/ncomms5999.
    [PMID: 25248036] IF 10,7420

  37. Acquired resistance to EGFR-targeted therapies in colorectal cancer.
    Van Emburgh BO, Sartore-Bianchi A, Di Nicolantonio F, Siena S, Bardelli A.
    Mol Oncol. 2014 Sep 12;8(6):1084-94. doi: 10.1016/j.molonc.2014.05.003. Epub 2014 May 14.
    [PMID: 24913799] IF 5,9350

  38. An EMMPRIN-γ-catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions.
    Moreno V, Gonzalo P, Gó-Escudero J, Pollán Á, Acín-Pérez R, Breckenridge M, Yáñez-Mó M, Barreiro O, Orsenigo F, Kadomatsu K, Chen CS, Enríquez JA, Dejana E, Sánchez-Madrid F, Arroyo AG.
    J Cell Sci. 2014 Sep 1;127(Pt 17):3768-81. doi: 10.1242/jcs.149518. Epub 2014 Jul 2.
    [PMID: 24994937] IF 5,3250

  39. PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo.
    Catucci I, Peterlongo P, Ciceri S, Colombo M, Pasquini G, Barile M, Bonanni B, Verderio P, Pizzamiglio S, Foglia C, Falanga A, Marchetti M, Galastri L, Bianchi T, Corna C, Ravagnani F, Bernard L, Fortuzzi S, Sardella D, Scuvera G, Peissel B, Manoukian S, et al.
    Genet Med. 2014 Sep;16(9):688-94. doi: 10.1038/gim.2014.13. Epub 2014 Feb 20.
    [PMID: 24556926] IF 6,4350

  40. Swi2/Snf2-like protein Uls1 functions in the Sgs1-dependent pathway of maintenance of rDNA stability and alleviation of replication stress.
    Kramarz K, Litwin I, Cal-Bakowska M, Szakal B, Branzei D, Wysocki R, Dziadkowiec D.
    DNA Repair (Amst). 2014 Sep;21:24-35. doi: 10.1016/j.dnarep.2014.05.008. Epub 2014 Jun 19.
    [PMID: 25091157] IF 3,3620

  41. The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination.
    Rolland Y, Marighetti P, Malinverno C, Confalonieri S, Luise C, Ducano N, Palamidessi A, Bisi S, Kajiho H, Troglio F, Shcherbakova OG, Dunn AR, Oldani A, Lanzetti L, Di Fiore PP, Disanza A, Scita G.
    Dev Cell. 2014 Sep 8;30(5):553-68. doi: 10.1016/j.devcel.2014.08.006.
    [PMID: 25203208] IF 10,3660

  42. RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.
    Lamba S, Russo M, Sun C, Lazzari L, Cancelliere C, Grernrum W, Lieftink C, Bernards R, Di Nicolantonio F, Bardelli A.
    Cell Rep. 2014 Sep 11;8(5):1475-83. doi: 10.1016/j.celrep.2014.07.033. Epub 2014 Sep 4.
    [PMID: 25199829] IF: 7,2070

  43. SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
    Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P.
    Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23.
    [PMID: 24859880] IF 5,8680

  44. AID and APOBEC deaminases: balancing DNA damage in epigenetics and immunity.
    Franchini DM, Petersen-Mahrt SK.
    Epigenomics. 2014;6(4):427-43. doi: 10.2217/epi.14.35.
    [PMID: 25333851] IF 5,2150

  45. Tumor vessel normalization by chloroquine independent of autophagy.
    Maes H, Kuchnio A, Peric A, Moens S, Nys K, De Bock K, Quaegebeur A, Schoors S, Georgiadou M, Wouters J, Vinckier S, Vankelecom H, Garmyn M, Vion AC, Radtke F, Boulanger C, Gerhardt H, Dejana E, Dewerchin M, Ghesquière B, Annaert W, Agostinis P, et al.
    Cancer Cell. 2014 Aug 11;26(2):190-206. doi: 10.1016/j.ccr.2014.06.025.
    [PMID: 25117709] IF 23,8930

  46. Processive DNA demethylation via DNA deaminase-induced lesion resolution.
    Franchini DM, Chan CF, Morgan H, Incorvaia E, Rangam G, Dean W, Santos F, Reik W, Petersen-Mahrt SK.
    PLoS One. 2014;9(7):e97754. doi: 10.1371/journal.pone.0097754.
    [PMID: 25025377] IF 3,5340

  47. CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.
    Cazzalini O, Sommatis S, Tillhon M, Dutto I, Bachi A, Rapp A, Nardo T, Scovassi AI, Necchi D, Cardoso MC, Stivala LA, Prosperi E.
    Nucleic Acids Res. 2014 Jul;42(13):8433-48. doi: 10.1093/nar/gku533. Epub 2014 Jun 17.
    [PMID: 24939902] IF 8,8080

  48. A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.
    Frittoli E, Palamidessi A, Marighetti P, Confalonieri S, Bianchi F, Malinverno C, Mazzarol G, Viale G, Martin-Padura I, Garré M, Parazzoli D, Mattei V, Cortellino S, Bertalot G, Di Fiore PP, Scita G.
    J Cell Biol. 2014 Jul 21;206(2):307-28. doi: 10.1083/jcb.201403127.
    [PMID: 25049275] IF 9,7860

  49. Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions.
    Zheng W, Nurmi H, Appak S, Sabine A, Bovay E, Korhonen EA, Orsenigo F, Lohela M, D'Amico G, Holopainen T, Leow CC, Dejana E, Petrova TV, Augustin HG, Alitalo K.
    Genes Dev. 2014 Jul 15;28(14):1592-603. doi: 10.1101/gad.237677.114.
    [PMID: 25030698] IF 12,6390

  50. A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.
    Gritenaite D, Princz LN, Szakal B, Bantele SC, Wendeler L, Schilbach S, Habermann BH, Matos J, Lisby M, Branzei D, Pfander B.
    Genes Dev. 2014 Jul 15;28(14):1604-19. doi: 10.1101/gad.240515.114.
    [PMID: 25030699] IF 12,6390

  51. ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.
    Kumar A, Mazzanti M, Mistrik M, Kosar M, Beznoussenko GV, Mironov AA, Garrè M, Parazzoli D, Shivashankar GV, Scita G, Bartek J, Foiani M.
    Cell. 2014 Jul 31;158(3):633-46. doi: 10.1016/j.cell.2014.05.046.
    [PMID: 25083873] IF 33,1160

  52. Mta2 promotes Tipin-dependent maintenance of replication fork integrity.
    Errico A, Aze A, Costanzo V.
    Cell Cycle. 2014 Jul 1;13(13):2120-8. doi: 10.4161/cc.29157. Epub 2014 May 15.
    [PMID: 24830473] IF 5,0060

  53. Orthodenticle is required for the development of olfactory projection neurons and local interneurons in Drosophila.
    Sen S, Biagini S, Reichert H, VijayRaghavan K.
    Biol Open. 2014 Jul 4;3(8):711-7. doi: 10.1242/bio.20148524.
    [PMID: 24996925]

  54. Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling.
    Boissan M, Montagnac G, Shen Q, Griparic L, Guitton J, Romao M, Sauvonnet N, Lagache T, Lascu I, Raposo G, Desbourdes C, Schlattner U, Lacombe ML, Polo S, van der Bliek AM, Roux A, Chavrier P.
    Science. 2014 Jun 27;344(6191):1510-5. doi: 10.1126/science.1253768.
    [PMID: 24970086] IF 31,4770

  55. Memo is a copper-dependent redox protein with an essential role in migration and metastasis.
    MacDonald G, Nalvarte I, Smirnova T, Vecchi M, Aceto N, Dolemeyer A, Frei A, Lienhard S, Wyckoff J, Hess D, Seebacher J, Keusch JJ, Gut H, Salaun D, Mazzarol G, Disalvatore D, Bentires-Alj M, Di Fiore PP, Badache A, Hynes NE.
    Sci Signal. 2014 Jun 10;7(329):ra56. doi: 10.1126/scisignal.2004870.
    [PMID: 24917593] IF 6,3370

  56. RILP regulates vacuolar ATPase through interaction with the V1G1 subunit.
    De Luca M, Cogli L, Progida C, Nisi V, Pascolutti R, Sigismund S, Di Fiore PP, Bucci C.
    J Cell Sci. 2014 Jun 15;127(Pt 12):2697-708. doi: 10.1242/jcs.142604. Epub 2014 Apr 24.
    [PMID: 24762812] IF 5,3250

  57. Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.
    Rossiello F, Herbig U, Longhese MP, Fumagalli M, d'Adda di Fagagna F.
    Curr Opin Genet Dev. 2014 Jun;26C:89-95. doi: 10.1016/j.gde.2014.06.009. Epub 2014 Aug 11.
    [PMID: 25104620] IF 8,5680

  58. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.
    Cheng CW, Adams GB, Perin L, Wei M, Zhou X, Lam BS, Da Sacco S, Mirisola M, Quinn DI, Dorff TB, Kopchick JJ, Longo VD.
    Cell Stem Cell. 2014 Jun 5;14(6):810-23. doi: 10.1016/j.stem.2014.04.014.
    [PMID: 24905167] IF: 22,1510

  59. Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation.
    Ogrunc M, Di Micco R, Liontos M, Bombardelli L, Mione M, Fumagalli M, Gorgoulis VG, d'Adda di Fagagna F.
    Cell Death Differ. 2014 Jun;21(6):998-1012. doi: 10.1038/cdd.2014.16. Epub 2014 Feb 28.
    [PMID: 24583638] IF: 8,3850

  60. Monitoring tumor-derived cell-free DNA in patients with solid tumors: clinical perspectives and research opportunities.
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  62. The deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesis.
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  63. Antibiotics counteract the worsening of airway remodelling induced by infections in asthma.
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  64. Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae.
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  65. Transcriptional regulation of arterial differentiation via Wnt, Sox and Notch.
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  66. Minimal residual disease in breast cancer: in blood veritas.
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  67. Vhs2 is a novel regulator of septin dynamics in budding yeast.
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  68. ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila.
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  69. The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.
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  71. Genetic predisposition to in situ and invasive lobular carcinoma of the breast.
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  73. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.
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  74. Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.
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  75. Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.
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  77. PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.
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  78. Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
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  79. ATM controls proper mitotic spindle structure.
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  80. Dangerous liaisons: MYCN meets condensins.
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  81. Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis.
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  82. ER-Golgi transport could occur in the absence of COPII vesicles.
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  84. VE-cadherin at a glance.
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  85. Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma.
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  86. Gene expression profiling reveals GC and CEACAM1 as new tools in the diagnosis of lung carcinoids.
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  87. Keeping EGFR signaling in check: ubiquitin is the guardian.
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  88. Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles.
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  89. DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.
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  90. Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer.
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  91. miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer.
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  92. Survival of neural stem cells undergoing DNA damage-induced astrocytic differentiation in self-renewal-promoting conditions in vitro.
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  93. Characterization of an Italian founder mutation in the RING-finger domain of BRCA1.
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  94. Immunohistochemical tools and techniques to visualize Notch in Drosophila melanogaster.
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  96. Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1).
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  97. Budding Yeast Swe1 Is Involved in the Control of Mitotic Spindle Elongation and Is Regulated by Cdc14 Phosphatase during Mitosis.
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  98. Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
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  99. Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
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  100. Golgi feels DNA's pain.
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  101. Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation.
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  102. Osteolytic bone metastasis is hampered by impinging on the interplay among autophagy, anoikis and ossification.
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  104. Climbing RAS, the everest of oncogenes.
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  105. Blood protein coating of gold nanoparticles as potential tool for organ targeting.
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