Pubblicazioni Massimiliano Pagani

Selected publications

1. Bonnal RJP, Rossetti G, Lugli E, De Simone M, Gruarin P, Brummelman J, Drufuca L, Passaro M, Bason R, Gervasoni F, Della Chiara G, D’Oria C, Martinovic M, Curti S, Ranzani V, Cordiglieri C, Alvisi G, Mazza EMC, Oliveto S, Silvestri Y, Carelli E, Mazzara S, Bosotti R, Sarnicola ML, Godano C, Bevilacqua V, Lorenzo M, Siena S, Bonoldi E, Sartore-Bianchi A, Amatu A, Veronesi G, Novellis P, Alloisio M, Giani A, Zucchini N, Opocher E, Mariani N, Pisani Ceretti A, Biffo S, Prati D, Bardelli A, Geginat J, Lanzavecchia A, Abrignani S, Pagani M.
   Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors associate with disease progression.
   Nature Immunology. 2021. https://doi.org/10.1038/s41590-021-00930-4>
   
2. Bocchi VD, Conforti P, Vezzoli E, Besusso D, Cappadona C, Lischetti T, Galimberti M, Ranzani V, Bonnal RJP, De Simone M, Rossetti G, He X, Kamimoto K, Espuny-Camacho I, Faedo A, Gervasoni F, Vuono R, Morris SA, Chen J, Felsenfeld D, Pavesi G, Barker RA, *Pagani M and Cattaneo E.
   The coding and long non-coding single-cell atlas of the developing human fetal striatum.
   Science. 2021. 10.1126/science.abf5759 *Corresponding author


3. Della Chiara G, Gervasoni F, Fakiola M, Godano C, D’Oria C, Azzolin L, Bonnal RJP, Moreni G, Drufuca L, Rossetti G, Ranzani V, Bason R, De Simone M, Panariello F, Ferrari I, Fabbris T, Zanconato F, Forcato M, Romano O, Caroli J, Gruarin P, Sarnicola ML, Cordenonsi M, Bardelli A, Zucchini N, Pisani Ceretti A, Mariani NM, Cassingena A, Sartore-Bianchi A, Testa G, Gianotti L, Opocher E, Pisati F, Tripodo C, Macino G, Siena S, Bicciato S, Piccolo S, Pagani M.
   Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ.
   Nature Communications: 10.1038/s41467-021-22544-y. 2021.


4. Passaro M, Martinovic M, Bevilacqua V, Hershberg EA, Rossetti G, Beliveau BJ, Bonnal RJP, Pagani M.
   OligoMinerApp: a web-server application for the design of genome-scale oligonucleotide in situ hybridization probes through the flexible OligoMiner environment.
   Nucleic Acids Res. 2020 Apr 20 PMID: 32313927


5. Arena S, Corti G, Durinikova E, Montone M, Reilly NM, Russo M, Lorenzato A, Arcella P, Lazzari L, Rospo G, Pagani M, Cancelliere C, Negrino C, Isella C, Bartolini A, Cassingena A, Amatu A, Mauri G, Sartore-Bianchi A, Mittica G, Medico E, Marsoni S, Linnebacher M, Abrignani S, Siena S, Di Nicolantonio F, Bardelli A.
   A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin.
   Clin Cancer Res. 2020 Mar 15;26(6):1372-1384. PMID: 31831554


6. Ricciardi S, Manfrini N, Alfieri R, Calamita P, Crosti MC, Gallo S, Müller R, Pagani M, Abrignani S, Biffo S.
   The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.
   Cell Metab. 2018 Dec 4;28(6):961. PMID: 30517897


7. Gruarin P, Maglie S, De Simone M, Häringer B, Vasco C, Ranzani V, Bosotti R, Noddings JS, Larghi P, Facciotti F, Sarnicola ML, Martinovic M, Crosti M, Moro M, Rossi RL, Bernardo ME, Caprioli F, Locatelli F, Rossetti G, Abrignani S, Pagani M, Geginat J.
   Eomesodermin controls a unique differentiation program in human IL-10 and IFN-γ coproducing regulatory T cells.
   Eur J Immunol. 2019 Jan;49(1):96-111.PMID: 30431161 Free article.


8. De Simone M, Rossetti G, Pagani M.
   Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges.
   Front Immunol. 2018 Jul 18;9:1638.


9. Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage? M.
   Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.
   Cell Rep. 2018 Jun 12;23(11):3262-3274.


10. Bodega B, Marasca F, Ranzani V, Cherubini A, Della Valle F, Neguembor MV, Wassef M, Zippo A, Lanzuolo C, Pagani M, Orlando V.
    A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.
    Nat Struct Mol Biol. 2017 May;24(5):444-452.


11. De Simone M, Arrigoni A, Rossetti G, Gruarin P, Ranzani V, Politano C, Bonnal RJP, Provasi E, Sarnicola ML, Panzeri I, Moro M, Crosti M, Mazzara S, Vaira V, Bosari S, Palleschi A, Santambrogio L, Bovo G, Zucchini N, Totis M, Gianotti L, Cesana G, Perego RA, Maroni N, Pisani Ceretti A, Opocher E, De Francesco R, Geginat J, Stunnenberg HG, Abrignani S, Pagani M.
    Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
    Immunity. 2016 Nov 15;45(5):1135-1147. PMID: 27851914


12. Ranzani V, Arrigoni A, Rossetti G, Panzeri I, Abrignani S, Bonnal RJ, Pagani M.
    Next-Generation Sequencing Analysis of Long Noncoding RNAs in CD4+ T Cell Differentiation.
    Methods Mol Biol. 2017;1514:173-185.


13. Bonnal RJ, Ranzani V, Arrigoni A, Curti S, Panzeri I, Gruarin P, Abrignani S, Rossetti G, Pagani M.
    De novo transcriptome profiling of highly purified human lymphocytes primary cells.
    Sci Data. 2015 Sep 29;2:150051.


14. Panzeri I, Rossetti G, Abrignani S, Pagani M.
    Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation.
    Front Immunol. 2015 Apr 15;6:175. PMID: 25926836


15. Bonnal RJ, Rossi RL, Carpi D, Ranzani V, Abrignani S, Pagani M.
    miRiadne: a web tool for consistent integration of miRNA nomenclature.
    Nucleic Acids Res. 2015 Jul 1;43(W1):W487-92. PMID: 25897123


16. Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal RJ, Curti S, Gruarin P, Provasi E, Sugliano E, Marconi M, De Francesco R, Geginat J, Bodega B, Abrignani S, Pagani M.
    The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.
    Nat Immunol. 2015 Mar;16(3):318-325. PMID: 25621826


17. Geginat J, Paroni M, Maglie S, Alfen JS, Kastirr I, Gruarin P, De Simone M, Pagani M, Abrignani S.
    Plasticity of human CD4 T cell subsets.
    Front Immunol. 2014 Dec 16;5:630.


18. Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, Pagani M, Bonaldi T, Ragoussis J, Friedman N, Camilloni G, Bianchi ME, Agresti A.
    Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.
    PLoS Biol. 2011 Jun;9(6):e1001086. PMID: 21738444


19. Grifantini R, Pagani M, Pierleoni A, Grandi A, Parri M, Campagnoli S, Pileri P, Cattaneo D, Canidio E, Pontillo A, De Camilli E, Bresciani A, Marinoni F, Pedrazzoli E, Nogarotto R, Abrignani S, Viale G, Sarmientos P, Grandi G.
    A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.
    J Proteomics. 2011 Dec 21;75(2):532-47. PMID: 21920474


20. Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, Pagani M, Bonaldi T, Ragoussis J, Friedman N, Camilloni G, Bianchi ME, Agresti A.
    Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.
    PLoS Biol. 2011 Jun;9(6):e1001086. PMID: 21738444


21. Rossi RL, Rossetti G, Wenandy L, Curti S, Ripamonti A, Bonnal RJ, Birolo RS, Moro M, Crosti MC, Gruarin P, Maglie S, Marabita F, Mascheroni D, Parente V, Comelli M, Trabucchi E, De Francesco R, Geginat J, Abrignani S, Pagani M.
    Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b.
    Nat Immunol. 2011 Jun 26;12(8):796-803.